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EIF3G (eukaryotic translation initiation factor 3 subunit G)

Identity

Alias_namesEIF3S4
eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa
eukaryotic translation initiation factor 3, subunit G
Alias_symbol (synonym)eIF3-delta
eIF3-p44
eIF3g
Other aliasEIF3-P42
HGNC (Hugo) EIF3G
LocusID (NCBI) 8666
Atlas_Id 62780
Location 19p13.2  [Link to chromosome band 19p13]
Location_base_pair Starts at 10115014 and ends at 10119924 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
EIF3G (19p13.2) / TSEN54 (17q25.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EIF3G   3274
Cards
Entrez_Gene (NCBI)EIF3G  8666  eukaryotic translation initiation factor 3 subunit G
AliasesEIF3-P42; EIF3S4; eIF3-delta; eIF3-p44
GeneCards (Weizmann)EIF3G
Ensembl hg19 (Hinxton)ENSG00000130811 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130811 [Gene_View]  chr19:10115014-10119924 [Contig_View]  EIF3G [Vega]
ICGC DataPortalENSG00000130811
TCGA cBioPortalEIF3G
AceView (NCBI)EIF3G
Genatlas (Paris)EIF3G
WikiGenes8666
SOURCE (Princeton)EIF3G
Genetics Home Reference (NIH)EIF3G
Genomic and cartography
GoldenPath hg38 (UCSC)EIF3G  -     chr19:10115014-10119924 -  19p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EIF3G  -     19p13.2   [Description]    (hg19-Feb_2009)
EnsemblEIF3G - 19p13.2 [CytoView hg19]  EIF3G - 19p13.2 [CytoView hg38]
Mapping of homologs : NCBIEIF3G [Mapview hg19]  EIF3G [Mapview hg38]
OMIM603913   
Gene and transcription
Genbank (Entrez)AA134976 AA588881 AF020833 AF094850 AK291320
RefSeq transcript (Entrez)NM_003755
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EIF3G
Cluster EST : UnigeneHs.529059 [ NCBI ]
CGAP (NCI)Hs.529059
Alternative Splicing GalleryENSG00000130811
Gene ExpressionEIF3G [ NCBI-GEO ]   EIF3G [ EBI - ARRAY_EXPRESS ]   EIF3G [ SEEK ]   EIF3G [ MEM ]
Gene Expression Viewer (FireBrowse)EIF3G [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8666
GTEX Portal (Tissue expression)EIF3G
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75821   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75821  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75821
Splice isoforms : SwissVarO75821
PhosPhoSitePlusO75821
Domaine pattern : Prosite (Expaxy)RRM (PS50102)   
Domains : Interpro (EBI)eIF3_g    eIF3g_N    eIF3G_RRM    Nucleotide-bd_a/b_plait    RRM_dom   
Domain families : Pfam (Sanger)eIF3g (PF12353)    RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam12353    pfam00076   
Domain families : Smart (EMBL)RRM (SM00360)  
Conserved Domain (NCBI)EIF3G
DMDM Disease mutations8666
Blocks (Seattle)EIF3G
PDB (SRS)2CQ0    2MJC    5K0Y   
PDB (PDBSum)2CQ0    2MJC    5K0Y   
PDB (IMB)2CQ0    2MJC    5K0Y   
PDB (RSDB)2CQ0    2MJC    5K0Y   
Structural Biology KnowledgeBase2CQ0    2MJC    5K0Y   
SCOP (Structural Classification of Proteins)2CQ0    2MJC    5K0Y   
CATH (Classification of proteins structures)2CQ0    2MJC    5K0Y   
SuperfamilyO75821
Human Protein AtlasENSG00000130811
Peptide AtlasO75821
HPRD04886
IPIIPI00290460   IPI00885107   
Protein Interaction databases
DIP (DOE-UCLA)O75821
IntAct (EBI)O75821
FunCoupENSG00000130811
BioGRIDEIF3G
STRING (EMBL)EIF3G
ZODIACEIF3G
Ontologies - Pathways
QuickGOO75821
Ontology : AmiGORNA binding  translation initiation factor activity  translation initiation factor activity  protein binding  nucleus  cytoplasm  cytosol  cytosol  eukaryotic translation initiation factor 3 complex  translational initiation  translational initiation  translational initiation  perinuclear region of cytoplasm  viral translational termination-reinitiation  
Ontology : EGO-EBIRNA binding  translation initiation factor activity  translation initiation factor activity  protein binding  nucleus  cytoplasm  cytosol  cytosol  eukaryotic translation initiation factor 3 complex  translational initiation  translational initiation  translational initiation  perinuclear region of cytoplasm  viral translational termination-reinitiation  
Pathways : KEGGRNA transport   
NDEx NetworkEIF3G
Atlas of Cancer Signalling NetworkEIF3G
Wikipedia pathwaysEIF3G
Orthology - Evolution
OrthoDB8666
GeneTree (enSembl)ENSG00000130811
Phylogenetic Trees/Animal Genes : TreeFamEIF3G
HOVERGENO75821
HOGENOMO75821
Homologs : HomoloGeneEIF3G
Homology/Alignments : Family Browser (UCSC)EIF3G
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEIF3G [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EIF3G
dbVarEIF3G
ClinVarEIF3G
1000_GenomesEIF3G 
Exome Variant ServerEIF3G
ExAC (Exome Aggregation Consortium)EIF3G (select the gene name)
Genetic variants : HAPMAP8666
Genomic Variants (DGV)EIF3G [DGVbeta]
DECIPHEREIF3G [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEIF3G 
Mutations
ICGC Data PortalEIF3G 
TCGA Data PortalEIF3G 
Broad Tumor PortalEIF3G
OASIS PortalEIF3G [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEIF3G  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEIF3G
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EIF3G
DgiDB (Drug Gene Interaction Database)EIF3G
DoCM (Curated mutations)EIF3G (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EIF3G (select a term)
intoGenEIF3G
Cancer3DEIF3G(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603913   
Orphanet
MedgenEIF3G
Genetic Testing Registry EIF3G
NextProtO75821 [Medical]
TSGene8666
GENETestsEIF3G
Target ValidationEIF3G
Huge Navigator EIF3G [HugePedia]
snp3D : Map Gene to Disease8666
BioCentury BCIQEIF3G
ClinGenEIF3G
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8666
Chemical/Pharm GKB GenePA162384827
Clinical trialEIF3G
Miscellaneous
canSAR (ICR)EIF3G (select the gene name)
Probes
Litterature
PubMed59 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEIF3G
EVEXEIF3G
GoPubMedEIF3G
iHOPEIF3G
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:06:58 CEST 2017

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