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EIF3I (eukaryotic translation initiation factor 3 subunit I)

Identity

Alias (NCBI)EIF3S2
PRO2242
TRIP-1
TRIP1
eIF3-beta
eIF3-p36
HGNC (Hugo) EIF3I
HGNC Alias symbTRIP-1
eIF3-beta
eIF3-p36
HGNC Previous nameEIF3S2
HGNC Previous nameeukaryotic translation initiation factor 3, subunit 2 beta, 36kDa
 eukaryotic translation initiation factor 3, subunit I
LocusID (NCBI) 8668
Atlas_Id 40426
Location 1p35.2  [Link to chromosome band 1p35]
Location_base_pair Starts at 32221584 and ends at 32231604 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EIF3I (1p35.1) / HDAC1 (1p35.1)EIF3I (1p35.1) / ST5 (11p15.4)LRRC47 (1p36.32) / EIF3I (1p35.1)
MTMR9LP (1p35.1) / EIF3I (1p35.1)SNRPA (19q13.2) / EIF3I (1p35.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)EIF3I   3272
Cards
Entrez_Gene (NCBI)EIF3I    eukaryotic translation initiation factor 3 subunit I
AliasesEIF3S2; PRO2242; TRIP-1; TRIP1; 
eIF3-beta; eIF3-p36
GeneCards (Weizmann)EIF3I
Ensembl hg19 (Hinxton)ENSG00000084623 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000084623 [Gene_View]  ENSG00000084623 [Sequence]  chr1:32221584-32231604 [Contig_View]  EIF3I [Vega]
ICGC DataPortalENSG00000084623
TCGA cBioPortalEIF3I
AceView (NCBI)EIF3I
Genatlas (Paris)EIF3I
SOURCE (Princeton)EIF3I
Genetics Home Reference (NIH)EIF3I
Genomic and cartography
GoldenPath hg38 (UCSC)EIF3I  -     chr1:32221584-32231604 +  1p35.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EIF3I  -     1p35.2   [Description]    (hg19-Feb_2009)
GoldenPathEIF3I - 1p35.2 [CytoView hg19]  EIF3I - 1p35.2 [CytoView hg38]
ImmunoBaseENSG00000084623
Genome Data Viewer NCBIEIF3I [Mapview hg19]  
OMIM603911   
Gene and transcription
Genbank (Entrez)AF116697 AK130633 AK222483 AK225024 AK289356
RefSeq transcript (Entrez)NM_001394168 NM_003757
Consensus coding sequences : CCDS (NCBI)EIF3I
Gene ExpressionEIF3I [ NCBI-GEO ]   EIF3I [ EBI - ARRAY_EXPRESS ]   EIF3I [ SEEK ]   EIF3I [ MEM ]
Gene Expression Viewer (FireBrowse)EIF3I [ Firebrowse - Broad ]
GenevisibleExpression of EIF3I in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8668
GTEX Portal (Tissue expression)EIF3I
Human Protein AtlasENSG00000084623-EIF3I [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13347   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13347  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13347
PhosPhoSitePlusQ13347
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)eIF3i    WD40/YVTN_repeat-like_dom_sf    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom    WD40_repeat_dom_sf   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)EIF3I
PDB (RSDB)6YBT    6ZMW    6ZON    6ZP4    6ZVJ    7A09   
PDB Europe6YBT    6ZMW    6ZON    6ZP4    6ZVJ    7A09   
PDB (PDBSum)6YBT    6ZMW    6ZON    6ZP4    6ZVJ    7A09   
PDB (IMB)6YBT    6ZMW    6ZON    6ZP4    6ZVJ    7A09   
Structural Biology KnowledgeBase6YBT    6ZMW    6ZON    6ZP4    6ZVJ    7A09   
SCOP (Structural Classification of Proteins)6YBT    6ZMW    6ZON    6ZP4    6ZVJ    7A09   
CATH (Classification of proteins structures)6YBT    6ZMW    6ZON    6ZP4    6ZVJ    7A09   
SuperfamilyQ13347
AlphaFold pdb e-kbQ13347   
Human Protein Atlas [tissue]ENSG00000084623-EIF3I [tissue]
HPRD04884
Protein Interaction databases
DIP (DOE-UCLA)Q13347
IntAct (EBI)Q13347
BioGRIDEIF3I
STRING (EMBL)EIF3I
ZODIACEIF3I
Ontologies - Pathways
QuickGOQ13347
Ontology : AmiGOformation of cytoplasmic translation initiation complex  cytoplasmic translational initiation  RNA binding  translation initiation factor activity  translation initiation factor activity  translation initiation factor activity  translation initiation factor activity  protein binding  cytosol  eukaryotic translation initiation factor 3 complex  translational initiation  translational initiation  translational initiation  eukaryotic 43S preinitiation complex  eukaryotic 48S preinitiation complex  extracellular exosome  eukaryotic translation initiation factor 3 complex, eIF3m  
Ontology : EGO-EBIformation of cytoplasmic translation initiation complex  cytoplasmic translational initiation  RNA binding  translation initiation factor activity  translation initiation factor activity  translation initiation factor activity  translation initiation factor activity  protein binding  cytosol  eukaryotic translation initiation factor 3 complex  translational initiation  translational initiation  translational initiation  eukaryotic 43S preinitiation complex  eukaryotic 48S preinitiation complex  extracellular exosome  eukaryotic translation initiation factor 3 complex, eIF3m  
Pathways : KEGGRNA transport   
NDEx NetworkEIF3I
Atlas of Cancer Signalling NetworkEIF3I
Wikipedia pathwaysEIF3I
Orthology - Evolution
OrthoDB8668
GeneTree (enSembl)ENSG00000084623
Phylogenetic Trees/Animal Genes : TreeFamEIF3I
Homologs : HomoloGeneEIF3I
Homology/Alignments : Family Browser (UCSC)EIF3I
Gene fusions - Rearrangements
Fusion : QuiverEIF3I
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEIF3I [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EIF3I
dbVarEIF3I
ClinVarEIF3I
MonarchEIF3I
1000_GenomesEIF3I 
Exome Variant ServerEIF3I
GNOMAD BrowserENSG00000084623
Varsome BrowserEIF3I
ACMGEIF3I variants
VarityQ13347
Genomic Variants (DGV)EIF3I [DGVbeta]
DECIPHEREIF3I [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEIF3I 
Mutations
ICGC Data PortalEIF3I 
TCGA Data PortalEIF3I 
Broad Tumor PortalEIF3I
OASIS PortalEIF3I [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEIF3I  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DEIF3I
Mutations and Diseases : HGMDEIF3I
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaEIF3I
DgiDB (Drug Gene Interaction Database)EIF3I
DoCM (Curated mutations)EIF3I
CIViC (Clinical Interpretations of Variants in Cancer)EIF3I
Cancer3DEIF3I
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603911   
Orphanet
DisGeNETEIF3I
MedgenEIF3I
Genetic Testing Registry EIF3I
NextProtQ13347 [Medical]
GENETestsEIF3I
Target ValidationEIF3I
Huge Navigator EIF3I [HugePedia]
ClinGenEIF3I
Clinical trials, drugs, therapy
MyCancerGenomeEIF3I
Protein Interactions : CTDEIF3I
Pharm GKB GenePA162384875
PharosQ13347
Clinical trialEIF3I
Miscellaneous
canSAR (ICR)EIF3I
HarmonizomeEIF3I
DataMed IndexEIF3I
Probes
Litterature
PubMed134 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXEIF3I
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:07:54 CEST 2021

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