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EIF3I (eukaryotic translation initiation factor 3 subunit I)

Identity

Alias_namesEIF3S2
eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa
eukaryotic translation initiation factor 3, subunit I
Alias_symbol (synonym)TRIP-1
eIF3-beta
eIF3-p36
eIF3i
Other aliasPRO2242
TRIP1
HGNC (Hugo) EIF3I
LocusID (NCBI) 8668
Atlas_Id 40426
Location 1p35.2  [Link to chromosome band 1p35]
Location_base_pair Starts at 32221584 and ends at 32231604 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EIF3I (1p35.1) / HDAC1 (1p35.1)EIF3I (1p35.1) / ST5 (11p15.4)LRRC47 (1p36.32) / EIF3I (1p35.1)
MTMR9LP (1p35.1) / EIF3I (1p35.1)SNRPA (19q13.2) / EIF3I (1p35.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EIF3I   3272
Cards
Entrez_Gene (NCBI)EIF3I  8668  eukaryotic translation initiation factor 3 subunit I
AliasesEIF3S2; PRO2242; TRIP-1; TRIP1; 
eIF3-beta; eIF3-p36
GeneCards (Weizmann)EIF3I
Ensembl hg19 (Hinxton)ENSG00000084623 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000084623 [Gene_View]  chr1:32221584-32231604 [Contig_View]  EIF3I [Vega]
ICGC DataPortalENSG00000084623
TCGA cBioPortalEIF3I
AceView (NCBI)EIF3I
Genatlas (Paris)EIF3I
WikiGenes8668
SOURCE (Princeton)EIF3I
Genetics Home Reference (NIH)EIF3I
Genomic and cartography
GoldenPath hg38 (UCSC)EIF3I  -     chr1:32221584-32231604 +  1p35.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EIF3I  -     1p35.2   [Description]    (hg19-Feb_2009)
EnsemblEIF3I - 1p35.2 [CytoView hg19]  EIF3I - 1p35.2 [CytoView hg38]
Mapping of homologs : NCBIEIF3I [Mapview hg19]  EIF3I [Mapview hg38]
OMIM603911   
Gene and transcription
Genbank (Entrez)AF116697 AK130633 AK222483 AK225024 AK289356
RefSeq transcript (Entrez)NM_003757
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EIF3I
Cluster EST : UnigeneHs.530096 [ NCBI ]
CGAP (NCI)Hs.530096
Alternative Splicing GalleryENSG00000084623
Gene ExpressionEIF3I [ NCBI-GEO ]   EIF3I [ EBI - ARRAY_EXPRESS ]   EIF3I [ SEEK ]   EIF3I [ MEM ]
Gene Expression Viewer (FireBrowse)EIF3I [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8668
GTEX Portal (Tissue expression)EIF3I
Human Protein AtlasENSG00000084623-EIF3I [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13347   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13347  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13347
Splice isoforms : SwissVarQ13347
PhosPhoSitePlusQ13347
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)eIF3i    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)EIF3I
DMDM Disease mutations8668
Blocks (Seattle)EIF3I
SuperfamilyQ13347
Human Protein Atlas [tissue]ENSG00000084623-EIF3I [tissue]
Peptide AtlasQ13347
HPRD04884
IPIIPI00012795   IPI00642205   
Protein Interaction databases
DIP (DOE-UCLA)Q13347
IntAct (EBI)Q13347
FunCoupENSG00000084623
BioGRIDEIF3I
STRING (EMBL)EIF3I
ZODIACEIF3I
Ontologies - Pathways
QuickGOQ13347
Ontology : AmiGOtranslation initiation factor activity  translation initiation factor activity  translation initiation factor activity  protein binding  cytosol  eukaryotic translation initiation factor 3 complex  translational initiation  translational initiation  translational initiation  extracellular exosome  eukaryotic translation initiation factor 3 complex, eIF3m  
Ontology : EGO-EBItranslation initiation factor activity  translation initiation factor activity  translation initiation factor activity  protein binding  cytosol  eukaryotic translation initiation factor 3 complex  translational initiation  translational initiation  translational initiation  extracellular exosome  eukaryotic translation initiation factor 3 complex, eIF3m  
Pathways : KEGGRNA transport   
NDEx NetworkEIF3I
Atlas of Cancer Signalling NetworkEIF3I
Wikipedia pathwaysEIF3I
Orthology - Evolution
OrthoDB8668
GeneTree (enSembl)ENSG00000084623
Phylogenetic Trees/Animal Genes : TreeFamEIF3I
HOVERGENQ13347
HOGENOMQ13347
Homologs : HomoloGeneEIF3I
Homology/Alignments : Family Browser (UCSC)EIF3I
Gene fusions - Rearrangements
Tumor Fusion PortalEIF3I
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEIF3I [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EIF3I
dbVarEIF3I
ClinVarEIF3I
1000_GenomesEIF3I 
Exome Variant ServerEIF3I
ExAC (Exome Aggregation Consortium)ENSG00000084623
GNOMAD BrowserENSG00000084623
Genetic variants : HAPMAP8668
Genomic Variants (DGV)EIF3I [DGVbeta]
DECIPHEREIF3I [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEIF3I 
Mutations
ICGC Data PortalEIF3I 
TCGA Data PortalEIF3I 
Broad Tumor PortalEIF3I
OASIS PortalEIF3I [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEIF3I  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEIF3I
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EIF3I
DgiDB (Drug Gene Interaction Database)EIF3I
DoCM (Curated mutations)EIF3I (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EIF3I (select a term)
intoGenEIF3I
Cancer3DEIF3I(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603911   
Orphanet
DisGeNETEIF3I
MedgenEIF3I
Genetic Testing Registry EIF3I
NextProtQ13347 [Medical]
TSGene8668
GENETestsEIF3I
Target ValidationEIF3I
Huge Navigator EIF3I [HugePedia]
snp3D : Map Gene to Disease8668
BioCentury BCIQEIF3I
ClinGenEIF3I
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8668
Chemical/Pharm GKB GenePA162384875
Clinical trialEIF3I
Miscellaneous
canSAR (ICR)EIF3I (select the gene name)
Probes
Litterature
PubMed73 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEIF3I
EVEXEIF3I
GoPubMedEIF3I
iHOPEIF3I
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:11:46 CET 2017

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