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EIF3K (eukaryotic translation initiation factor 3 subunit K)

Identity

Alias_namesEIF3S12
eukaryotic translation initiation factor 3, subunit 12
eukaryotic translation initiation factor 3, subunit K
Alias_symbol (synonym)eIF3k
PRO1474
HSPC029
PTD001
PLAC-24
M9
ARG134
Other aliasEIF3-p28
MSTP001
PLAC24
HGNC (Hugo) EIF3K
LocusID (NCBI) 27335
Atlas_Id 52996
Location 19q13.2  [Link to chromosome band 19q13]
Location_base_pair Starts at 38619074 and ends at 38636959 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ECH1 (19q13.2) / EIF3K (19q13.2)EIF3K (19q13.2) / ACTN4 (19q13.2)EIF3K (19q13.2) / CYP39A1 (6p12.3)
EIF3K (19q13.2) / PGK1 (Xq21.1)EIF3K (19q13.2) / STMN3 (20q13.33)SLC45A1 (1p36.23) / EIF3K (19q13.2)
EIF3K 19q13.2 / CYP39A1 6p12.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EIF3K   24656
Cards
Entrez_Gene (NCBI)EIF3K  27335  eukaryotic translation initiation factor 3 subunit K
AliasesARG134; EIF3-p28; EIF3S12; HSPC029; 
M9; MSTP001; PLAC-24; PLAC24; PRO1474; PTD001
GeneCards (Weizmann)EIF3K
Ensembl hg19 (Hinxton)ENSG00000178982 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000178982 [Gene_View]  chr19:38619074-38636959 [Contig_View]  EIF3K [Vega]
ICGC DataPortalENSG00000178982
TCGA cBioPortalEIF3K
AceView (NCBI)EIF3K
Genatlas (Paris)EIF3K
WikiGenes27335
SOURCE (Princeton)EIF3K
Genetics Home Reference (NIH)EIF3K
Genomic and cartography
GoldenPath hg38 (UCSC)EIF3K  -     chr19:38619074-38636959 +  19q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EIF3K  -     19q13.2   [Description]    (hg19-Feb_2009)
EnsemblEIF3K - 19q13.2 [CytoView hg19]  EIF3K - 19q13.2 [CytoView hg38]
Mapping of homologs : NCBIEIF3K [Mapview hg19]  EIF3K [Mapview hg38]
OMIM609596   
Gene and transcription
Genbank (Entrez)AB019392 AF077051 AF085358 AF109355 AF315506
RefSeq transcript (Entrez)NM_001300992 NM_001308393 NM_013234
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EIF3K
Cluster EST : UnigeneHs.314359 [ NCBI ]
CGAP (NCI)Hs.314359
Alternative Splicing GalleryENSG00000178982
Gene ExpressionEIF3K [ NCBI-GEO ]   EIF3K [ EBI - ARRAY_EXPRESS ]   EIF3K [ SEEK ]   EIF3K [ MEM ]
Gene Expression Viewer (FireBrowse)EIF3K [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27335
GTEX Portal (Tissue expression)EIF3K
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UBQ5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UBQ5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UBQ5
Splice isoforms : SwissVarQ9UBQ5
PhosPhoSitePlusQ9UBQ5
Domains : Interpro (EBI)ARM-type_fold    CSN8_PSD8_EIF3K    eIF3k    Transl_init_fac_sub12_N_euk    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)CSN8_PSD8_EIF3K (PF10075)   
Domain families : Pfam (NCBI)pfam10075   
Conserved Domain (NCBI)EIF3K
DMDM Disease mutations27335
Blocks (Seattle)EIF3K
PDB (SRS)1RZ4    3J8B    3J8C   
PDB (PDBSum)1RZ4    3J8B    3J8C   
PDB (IMB)1RZ4    3J8B    3J8C   
PDB (RSDB)1RZ4    3J8B    3J8C   
Structural Biology KnowledgeBase1RZ4    3J8B    3J8C   
SCOP (Structural Classification of Proteins)1RZ4    3J8B    3J8C   
CATH (Classification of proteins structures)1RZ4    3J8B    3J8C   
SuperfamilyQ9UBQ5
Human Protein AtlasENSG00000178982
Peptide AtlasQ9UBQ5
HPRD11740
IPIIPI00033143   IPI01014198   IPI01013095   
Protein Interaction databases
DIP (DOE-UCLA)Q9UBQ5
IntAct (EBI)Q9UBQ5
FunCoupENSG00000178982
BioGRIDEIF3K
STRING (EMBL)EIF3K
ZODIACEIF3K
Ontologies - Pathways
QuickGOQ9UBQ5
Ontology : AmiGOtranslation initiation factor activity  translation initiation factor activity  protein binding  nucleus  cytosol  cytosol  eukaryotic translation initiation factor 3 complex  translational initiation  translational initiation  translational initiation  regulation of translational initiation  membrane  ribosome binding  extracellular exosome  
Ontology : EGO-EBItranslation initiation factor activity  translation initiation factor activity  protein binding  nucleus  cytosol  cytosol  eukaryotic translation initiation factor 3 complex  translational initiation  translational initiation  translational initiation  regulation of translational initiation  membrane  ribosome binding  extracellular exosome  
NDEx NetworkEIF3K
Atlas of Cancer Signalling NetworkEIF3K
Wikipedia pathwaysEIF3K
Orthology - Evolution
OrthoDB27335
GeneTree (enSembl)ENSG00000178982
Phylogenetic Trees/Animal Genes : TreeFamEIF3K
HOVERGENQ9UBQ5
HOGENOMQ9UBQ5
Homologs : HomoloGeneEIF3K
Homology/Alignments : Family Browser (UCSC)EIF3K
Gene fusions - Rearrangements
Fusion : MitelmanEIF3K/CYP39A1 [19q13.2/6p12.3]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEIF3K [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EIF3K
dbVarEIF3K
ClinVarEIF3K
1000_GenomesEIF3K 
Exome Variant ServerEIF3K
ExAC (Exome Aggregation Consortium)EIF3K (select the gene name)
Genetic variants : HAPMAP27335
Genomic Variants (DGV)EIF3K [DGVbeta]
DECIPHEREIF3K [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEIF3K 
Mutations
ICGC Data PortalEIF3K 
TCGA Data PortalEIF3K 
Broad Tumor PortalEIF3K
OASIS PortalEIF3K [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEIF3K  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEIF3K
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EIF3K
DgiDB (Drug Gene Interaction Database)EIF3K
DoCM (Curated mutations)EIF3K (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EIF3K (select a term)
intoGenEIF3K
Cancer3DEIF3K(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609596   
Orphanet
MedgenEIF3K
Genetic Testing Registry EIF3K
NextProtQ9UBQ5 [Medical]
TSGene27335
GENETestsEIF3K
Target ValidationEIF3K
Huge Navigator EIF3K [HugePedia]
snp3D : Map Gene to Disease27335
BioCentury BCIQEIF3K
ClinGenEIF3K
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27335
Chemical/Pharm GKB GenePA162384923
Clinical trialEIF3K
Miscellaneous
canSAR (ICR)EIF3K (select the gene name)
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEIF3K
EVEXEIF3K
GoPubMedEIF3K
iHOPEIF3K
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Wed Jun 7 12:32:21 CEST 2017

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