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EIF4E1B (eukaryotic translation initiation factor 4E family member 1B)

Identity

Alias_symbol (synonym)FLJ36951
Other alias-
HGNC (Hugo) EIF4E1B
LocusID (NCBI) 253314
Atlas_Id 62784
Location 5q35.2  [Link to chromosome band 5q35]
Location_base_pair Starts at 176630682 and ends at 176646641 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EIF4E1B   33179
Cards
Entrez_Gene (NCBI)EIF4E1B  253314  eukaryotic translation initiation factor 4E family member 1B
Aliases
GeneCards (Weizmann)EIF4E1B
Ensembl hg19 (Hinxton)ENSG00000175766 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175766 [Gene_View]  chr5:176630682-176646641 [Contig_View]  EIF4E1B [Vega]
ICGC DataPortalENSG00000175766
TCGA cBioPortalEIF4E1B
AceView (NCBI)EIF4E1B
Genatlas (Paris)EIF4E1B
WikiGenes253314
SOURCE (Princeton)EIF4E1B
Genetics Home Reference (NIH)EIF4E1B
Genomic and cartography
GoldenPath hg38 (UCSC)EIF4E1B  -     chr5:176630682-176646641 +  5q35.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EIF4E1B  -     5q35.2   [Description]    (hg19-Feb_2009)
EnsemblEIF4E1B - 5q35.2 [CytoView hg19]  EIF4E1B - 5q35.2 [CytoView hg38]
Mapping of homologs : NCBIEIF4E1B [Mapview hg19]  EIF4E1B [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK094270 BM709255 DA689940 DR008159 DR731203
RefSeq transcript (Entrez)NM_001099408
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EIF4E1B
Cluster EST : UnigeneHs.448362 [ NCBI ]
CGAP (NCI)Hs.448362
Alternative Splicing GalleryENSG00000175766
Gene ExpressionEIF4E1B [ NCBI-GEO ]   EIF4E1B [ EBI - ARRAY_EXPRESS ]   EIF4E1B [ SEEK ]   EIF4E1B [ MEM ]
Gene Expression Viewer (FireBrowse)EIF4E1B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)253314
GTEX Portal (Tissue expression)EIF4E1B
Protein : pattern, domain, 3D structure
UniProt/SwissProtA6NMX2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA6NMX2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA6NMX2
Splice isoforms : SwissVarA6NMX2
PhosPhoSitePlusA6NMX2
Domaine pattern : Prosite (Expaxy)IF4E (PS00813)   
Domains : Interpro (EBI)TIF_eIF4e-like    TIF_eIF_4E    TIF_eIF_4E_CS   
Domain families : Pfam (Sanger)IF4E (PF01652)   
Domain families : Pfam (NCBI)pfam01652   
Conserved Domain (NCBI)EIF4E1B
DMDM Disease mutations253314
Blocks (Seattle)EIF4E1B
SuperfamilyA6NMX2
Human Protein AtlasENSG00000175766
Peptide AtlasA6NMX2
IPIIPI00852709   IPI00964941   IPI00965353   
Protein Interaction databases
DIP (DOE-UCLA)A6NMX2
IntAct (EBI)A6NMX2
FunCoupENSG00000175766
BioGRIDEIF4E1B
STRING (EMBL)EIF4E1B
ZODIACEIF4E1B
Ontologies - Pathways
QuickGOA6NMX2
Ontology : AmiGOtranslation initiation factor activity  cytoplasm  mRNA cap binding complex  translational initiation  regulation of translation  
Ontology : EGO-EBItranslation initiation factor activity  cytoplasm  mRNA cap binding complex  translational initiation  regulation of translation  
Pathways : KEGGRNA transport    HIF-1 signaling pathway    mTOR signaling pathway    PI3K-Akt signaling pathway    Insulin signaling pathway   
NDEx NetworkEIF4E1B
Atlas of Cancer Signalling NetworkEIF4E1B
Wikipedia pathwaysEIF4E1B
Orthology - Evolution
OrthoDB253314
GeneTree (enSembl)ENSG00000175766
Phylogenetic Trees/Animal Genes : TreeFamEIF4E1B
HOVERGENA6NMX2
HOGENOMA6NMX2
Homologs : HomoloGeneEIF4E1B
Homology/Alignments : Family Browser (UCSC)EIF4E1B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEIF4E1B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EIF4E1B
dbVarEIF4E1B
ClinVarEIF4E1B
1000_GenomesEIF4E1B 
Exome Variant ServerEIF4E1B
ExAC (Exome Aggregation Consortium)EIF4E1B (select the gene name)
Genetic variants : HAPMAP253314
Genomic Variants (DGV)EIF4E1B [DGVbeta]
DECIPHEREIF4E1B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEIF4E1B 
Mutations
ICGC Data PortalEIF4E1B 
TCGA Data PortalEIF4E1B 
Broad Tumor PortalEIF4E1B
OASIS PortalEIF4E1B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEIF4E1B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEIF4E1B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EIF4E1B
DgiDB (Drug Gene Interaction Database)EIF4E1B
DoCM (Curated mutations)EIF4E1B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EIF4E1B (select a term)
intoGenEIF4E1B
Cancer3DEIF4E1B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenEIF4E1B
Genetic Testing Registry EIF4E1B
NextProtA6NMX2 [Medical]
TSGene253314
GENETestsEIF4E1B
Target ValidationEIF4E1B
Huge Navigator EIF4E1B [HugePedia]
snp3D : Map Gene to Disease253314
BioCentury BCIQEIF4E1B
ClinGenEIF4E1B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD253314
Chemical/Pharm GKB GenePA162384974
Clinical trialEIF4E1B
Miscellaneous
canSAR (ICR)EIF4E1B (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEIF4E1B
EVEXEIF4E1B
GoPubMedEIF4E1B
iHOPEIF4E1B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:46:58 CEST 2017

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