Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

EIF4EBP2 (eukaryotic translation initiation factor 4E binding protein 2)

Identity

Other alias4EBP2
PHASII
HGNC (Hugo) EIF4EBP2
LocusID (NCBI) 1979
Atlas_Id 51579
Location 10q22.1  [Link to chromosome band 10q22]
Location_base_pair Starts at 70404105 and ends at 70428618 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CEP83 (12q22) / EIF4EBP2 (10q22.1)EIF4EBP2 (10q22.1) / EIF4EBP2 (10q22.1)EIF4EBP2 (10q22.1) / GSTM1 (1p13.3)
LDHA (11p15.1) / EIF4EBP2 (10q22.1)SERPING1 (11q12.1) / EIF4EBP2 (10q22.1)SSBP3 (1p32.3) / EIF4EBP2 (10q22.1)
TBCB (19q13.12) / EIF4EBP2 (10q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EIF4EBP2   3289
Cards
Entrez_Gene (NCBI)EIF4EBP2  1979  eukaryotic translation initiation factor 4E binding protein 2
Aliases4EBP2; PHASII
GeneCards (Weizmann)EIF4EBP2
Ensembl hg19 (Hinxton)ENSG00000148730 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148730 [Gene_View]  chr10:70404105-70428618 [Contig_View]  EIF4EBP2 [Vega]
ICGC DataPortalENSG00000148730
TCGA cBioPortalEIF4EBP2
AceView (NCBI)EIF4EBP2
Genatlas (Paris)EIF4EBP2
WikiGenes1979
SOURCE (Princeton)EIF4EBP2
Genetics Home Reference (NIH)EIF4EBP2
Genomic and cartography
GoldenPath hg38 (UCSC)EIF4EBP2  -     chr10:70404105-70428618 +  10q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EIF4EBP2  -     10q22.1   [Description]    (hg19-Feb_2009)
EnsemblEIF4EBP2 - 10q22.1 [CytoView hg19]  EIF4EBP2 - 10q22.1 [CytoView hg38]
Mapping of homologs : NCBIEIF4EBP2 [Mapview hg19]  EIF4EBP2 [Mapview hg38]
OMIM602224   
Gene and transcription
Genbank (Entrez)AK001936 AK057643 AK313724 BC005057 BC015007
RefSeq transcript (Entrez)NM_004096
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EIF4EBP2
Cluster EST : UnigeneHs.730236 [ NCBI ]
CGAP (NCI)Hs.730236
Alternative Splicing GalleryENSG00000148730
Gene ExpressionEIF4EBP2 [ NCBI-GEO ]   EIF4EBP2 [ EBI - ARRAY_EXPRESS ]   EIF4EBP2 [ SEEK ]   EIF4EBP2 [ MEM ]
Gene Expression Viewer (FireBrowse)EIF4EBP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1979
GTEX Portal (Tissue expression)EIF4EBP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13542   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13542  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13542
Splice isoforms : SwissVarQ13542
PhosPhoSitePlusQ13542
Domains : Interpro (EBI)EIF4EBP   
Domain families : Pfam (Sanger)eIF_4EBP (PF05456)   
Domain families : Pfam (NCBI)pfam05456   
Conserved Domain (NCBI)EIF4EBP2
DMDM Disease mutations1979
Blocks (Seattle)EIF4EBP2
PDB (SRS)2MX4    3AM7   
PDB (PDBSum)2MX4    3AM7   
PDB (IMB)2MX4    3AM7   
PDB (RSDB)2MX4    3AM7   
Structural Biology KnowledgeBase2MX4    3AM7   
SCOP (Structural Classification of Proteins)2MX4    3AM7   
CATH (Classification of proteins structures)2MX4    3AM7   
SuperfamilyQ13542
Human Protein AtlasENSG00000148730
Peptide AtlasQ13542
HPRD03747
IPIIPI00002570   IPI00743761   
Protein Interaction databases
DIP (DOE-UCLA)Q13542
IntAct (EBI)Q13542
FunCoupENSG00000148730
BioGRIDEIF4EBP2
STRING (EMBL)EIF4EBP2
ZODIACEIF4EBP2
Ontologies - Pathways
QuickGOQ13542
Ontology : AmiGOprotein binding  cytoplasm  translation  memory  eukaryotic initiation factor 4E binding  eukaryotic initiation factor 4E binding  insulin receptor signaling pathway  cAMP-mediated signaling  translation repressor activity  TOR signaling  social behavior  negative regulation of translational initiation  negative regulation of translational initiation  regulation of synaptic plasticity  modulation of synaptic transmission  
Ontology : EGO-EBIprotein binding  cytoplasm  translation  memory  eukaryotic initiation factor 4E binding  eukaryotic initiation factor 4E binding  insulin receptor signaling pathway  cAMP-mediated signaling  translation repressor activity  TOR signaling  social behavior  negative regulation of translational initiation  negative regulation of translational initiation  regulation of synaptic plasticity  modulation of synaptic transmission  
NDEx NetworkEIF4EBP2
Atlas of Cancer Signalling NetworkEIF4EBP2
Wikipedia pathwaysEIF4EBP2
Orthology - Evolution
OrthoDB1979
GeneTree (enSembl)ENSG00000148730
Phylogenetic Trees/Animal Genes : TreeFamEIF4EBP2
HOVERGENQ13542
HOGENOMQ13542
Homologs : HomoloGeneEIF4EBP2
Homology/Alignments : Family Browser (UCSC)EIF4EBP2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEIF4EBP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EIF4EBP2
dbVarEIF4EBP2
ClinVarEIF4EBP2
1000_GenomesEIF4EBP2 
Exome Variant ServerEIF4EBP2
ExAC (Exome Aggregation Consortium)EIF4EBP2 (select the gene name)
Genetic variants : HAPMAP1979
Genomic Variants (DGV)EIF4EBP2 [DGVbeta]
DECIPHEREIF4EBP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEIF4EBP2 
Mutations
ICGC Data PortalEIF4EBP2 
TCGA Data PortalEIF4EBP2 
Broad Tumor PortalEIF4EBP2
OASIS PortalEIF4EBP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEIF4EBP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEIF4EBP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EIF4EBP2
DgiDB (Drug Gene Interaction Database)EIF4EBP2
DoCM (Curated mutations)EIF4EBP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EIF4EBP2 (select a term)
intoGenEIF4EBP2
Cancer3DEIF4EBP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602224   
Orphanet
MedgenEIF4EBP2
Genetic Testing Registry EIF4EBP2
NextProtQ13542 [Medical]
TSGene1979
GENETestsEIF4EBP2
Target ValidationEIF4EBP2
Huge Navigator EIF4EBP2 [HugePedia]
snp3D : Map Gene to Disease1979
BioCentury BCIQEIF4EBP2
ClinGenEIF4EBP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1979
Chemical/Pharm GKB GenePA27716
Clinical trialEIF4EBP2
Miscellaneous
canSAR (ICR)EIF4EBP2 (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEIF4EBP2
EVEXEIF4EBP2
GoPubMedEIF4EBP2
iHOPEIF4EBP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:32:22 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.