| Nomenclature | | HGNC (Hugo) | EIF4G1 3296 |
| Entrez_Gene (NCBI) | EIF4G1 1981 eukaryotic translation initiation factor 4 gamma, 1 |
| Cards | | GeneCards (Weizmann) | EIF4G1 |
| Ensembl (Hinxton) | ENSG00000114867 [Gene_View] chr3:184032283-184053146 [Contig_View] EIF4G1 [Vega] |
| AceView (NCBI) | EIF4G1 |
| Genatlas (Paris) | EIF4G1 |
| SOURCE (Stanford) | NM_001194946 NM_001194947 NM_004953 NM_182917 NM_198241 NM_198242 NM_198244 |
| Genomic and cartography | | GoldenPath (UCSC) | EIF4G1 - 3q27.1 chr3:184032283-184053146 + 3q27.1 [Description] (hg19-Feb_2009) |
| Ensembl | EIF4G1 - 3q27.1 [CytoView] |
| Mapping of homologs : NCBI | EIF4G1 [Mapview] |
| OMIM | 600495 614251 |
| Gene and transcription |
| Genbank (Entrez) | AB210013 AF002815 AF002816 AF104913 AF281070 |
| RefSeq transcript (SRS) | NM_001194946 NM_001194947 NM_004953 NM_182917 NM_198241 NM_198242 NM_198244 |
| RefSeq transcript (Entrez) | NM_001194946 NM_001194947 NM_004953 NM_182917 NM_198241 NM_198242 NM_198244 |
| RefSeq genomic (SRS) | AC_000135 NC_000003 NC_018914 NG_016850 NT_005612 NW_001838884 NW_004078013 |
| RefSeq genomic (Entrez) | AC_000135 NC_000003 NC_018914 NG_016850 NT_005612 NW_001838884 NW_004078013 |
| Consensus coding sequences : CCDS (NCBI) | EIF4G1 |
| Cluster EST : Unigene | Hs.433750 [ SRS ] Hs.433750 [ NCBI ] |
| CGAP (NCI) | Hs.433750 |
| Alternative Splicing : Fast-db (Paris) | GSHG0021382 |
| Alternative Splicing Gallery | ENSG00000114867 |
| Gene Expression | EIF4G1 [ NCBI-GEO ] EIF4G1 [ EBI - ARRAY_EXPRESS ] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q04637 (SRS) Q04637 (Uniprot) |
| NextProt | Q04637 |
| With graphics : InterPro | Q04637 |
| Splice isoforms : SwissVar | Q04637(Swissvar) |
| Domaine pattern : Prosite (SRS) | MI (PS51366) W2 (PS51363) |
| Domaine pattern : Prosite (Expaxy) | MI (PS51366) W2 (PS51363) |
| Domains : Interpro (SRS) | ARM-type_fold Initiation_fac_eIF4g_MI MIF4-like_typ_1/2/3 MIF4G-like_typ-3 W2_domain |
| Domains : Interpro (EBI) | ARM-type_fold Initiation_fac_eIF4g_MI MIF4-like_typ_1/2/3 MIF4G-like_typ-3 W2_domain |
| Related proteins : CluSTr | Q04637 |
| Domain families : Pfam (SRS) | MA3 (PF02847) MIF4G (PF02854) W2 (PF02020) |
| Domain families : Pfam (Sanger) | MA3 (PF02847) MIF4G (PF02854) W2 (PF02020) |
| Domain families : Pfam (NCBI) | pfam02847 pfam02854 pfam02020 |
| Domain families : Smart (EMBL) | eIF5C (SM00515) MA3 (SM00544) MIF4G (SM00543) |
| DMDM | 1981 |
| Blocks (Seattle) | Q04637 |
| PDB (SRS) | 1LJ2 1UG3 2W97 4F02 |
| PDB (PDBSum) | 1LJ2 1UG3 2W97 4F02 |
| PDB (IMB) | 1LJ2 1UG3 2W97 4F02 |
| PDB (RSDB) | 1LJ2 1UG3 2W97 4F02 |
| Human Protein Atlas | ENSG00000114867 |
| HPRD | 06774 |
| IPI | IPI00552639 IPI00955980 IPI00759560 IPI00798400 IPI00386533 IPI00953292 IPI00479262 IPI00926603 IPI00926210 IPI00926013 IPI00925434 IPI00925057 IPI00927510 IPI00956559 IPI00926917 IPI00926681 IPI00926457 IPI00926237 IPI00926127 IPI00925658 IPI00925407 IPI01009369 IPI00925493 IPI00925263 IPI00925050 IPI00924828 IPI00927765 IPI01015364 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q04637 |
| IntAct (EBI) | Q04637 |
| FunCoup | ENSG00000114867 |
| REACTOME | EIF4G1 |
| Protein Interaction Database | 1981 |
| BioGRID | EIF4G1 |
| InParanoid | Q04637 |
| Interologous Interaction database | Q04637 |
| IntegromeDB | EIF4G1 |
| Polymorphism : SNP, mutations, diseases | | SNP Single Nucleotide Polymorphism (NCBI) | EIF4G1 |
| SNP (GeneSNP Utah) | EIF4G1 |
| SNP : HGBase | EIF4G1 |
| Genetic variants : HAPMAP | EIF4G1 |
| Somatic Mutations in Cancer : COSMIC | EIF4G1 |
| CONAN: Copy Number Analysis | EIF4G1 |
| Mutations and Diseases : HGMD | EIF4G1 |
| OMIM | 600495 614251 |
| GENETests | 600495 614251 |
| Disease Genetic Association | EIF4G1 |
| Huge Navigator |
EIF4G1 [HugePedia] EIF4G1 [HugeCancerGEM] |
| Genomic Variants | EIF4G1 EIF4G1 [DGVbeta] |
| snp3D : Map Gene to Disease | 1981 |
| General knowledge |
|---|
| Homologs : HomoloGene | EIF4G1 |
| Homology/Alignments : Family Browser (UCSC) | EIF4G1 |
| Phylogenetic Trees/Animal Genes : TreeFam | EIF4G1 |
| Chemical/Protein Interactions : CTD | 1981 |
| Chemical/Pharm GKB Gene | PA27722 |
| Clinical trial | EIF4G1 |
| Cancer Resource (Charite) | ENSG00000114867 |
| Ontology : AmiGO | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay nuclear-transcribed mRNA poly(A) tail shortening DNA binding translation initiation factor activity protein binding cytoplasm cytosol translation translational initiation regulation of translational initiation regulation of translational initiation translation factor activity, nucleic acid binding cell death insulin receptor signaling pathway gene expression RNA metabolic process mRNA metabolic process eukaryotic translation initiation factor 4F complex virus-host interaction cytokine-mediated signaling pathway cellular protein metabolic process |
| Ontology : EGO-EBI | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay nuclear-transcribed mRNA poly(A) tail shortening DNA binding translation initiation factor activity protein binding cytoplasm cytosol translation translational initiation regulation of translational initiation regulation of translational initiation translation factor activity, nucleic acid binding cell death insulin receptor signaling pathway gene expression RNA metabolic process mRNA metabolic process eukaryotic translation initiation factor 4F complex virus-host interaction cytokine-mediated signaling pathway cellular protein metabolic process |
| Pathways : BIOCARTA | mTOR Signaling Pathway [Genes] Internal Ribosome entry pathway [Genes] Regulation of eIF4e and p70 S6 Kinase [Genes] Eukaryotic protein translation [Genes] |
| Other databases |
| Probes |
|---|
| Litterature | | PubMed | 141 Pubmed reference(s) in Entrez |
| PubGene | EIF4G1 |
| iHOP | EIF4G1 |
