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EIF4G3 (eukaryotic translation initiation factor 4 gamma, 3)

Identity

Other nameseIF-4G 3
eIF4G 3
eIF4GII
HGNC (Hugo) EIF4G3
LocusID (NCBI) 8672
Location 1p36.12
Location_base_pair Starts at 21132785 and ends at 21503381 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)EIF4G3   3298
Cards
Entrez_Gene (NCBI)EIF4G3  8672  eukaryotic translation initiation factor 4 gamma, 3
GeneCards (Weizmann)EIF4G3
Ensembl (Hinxton)ENSG00000075151 [Gene_View]  chr1:21132785-21503381 [Contig_View]  EIF4G3 [Vega]
ICGC DataPortalENSG00000075151
cBioPortalEIF4G3
AceView (NCBI)EIF4G3
Genatlas (Paris)EIF4G3
WikiGenes8672
SOURCE (Princeton)NM_001198801 NM_001198802 NM_001198803 NM_003760
Genomic and cartography
GoldenPath (UCSC)EIF4G3  -  1p36.12   chr1:21132785-21503381 -  1p36.12   [Description]    (hg19-Feb_2009)
EnsemblEIF4G3 - 1p36.12 [CytoView]
Mapping of homologs : NCBIEIF4G3 [Mapview]
OMIM603929   
Gene and transcription
Genbank (Entrez)AB209119 AF012072 AK225489 AK294883 AK302087
RefSeq transcript (Entrez)NM_001198801 NM_001198802 NM_001198803 NM_003760
RefSeq genomic (Entrez)AC_000133 NC_000001 NC_018912 NT_032977 NW_001838573 NW_004929289
Consensus coding sequences : CCDS (NCBI)EIF4G3
Cluster EST : UnigeneHs.732241 [ NCBI ]
CGAP (NCI)Hs.732241
Alternative Splicing : Fast-db (Paris)GSHG0001828
Alternative Splicing GalleryENSG00000075151
Gene ExpressionEIF4G3 [ NCBI-GEO ]     EIF4G3 [ SEEK ]   EIF4G3 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43432 (Uniprot)
NextProtO43432  [Medical]
With graphics : InterProO43432
Splice isoforms : SwissVarO43432 (Swissvar)
Domaine pattern : Prosite (Expaxy)MI (PS51366)    W2 (PS51363)   
Domains : Interpro (EBI)ARM-type_fold [organisation]   Initiation_fac_eIF4g_MI [organisation]   MIF4-like_typ_1/2/3 [organisation]   MIF4G-like_typ-3 [organisation]   W2_domain [organisation]  
Related proteins : CluSTrO43432
Domain families : Pfam (Sanger)MA3 (PF02847)    MIF4G (PF02854)    W2 (PF02020)   
Domain families : Pfam (NCBI)pfam02847    pfam02854    pfam02020   
Domain families : Smart (EMBL)eIF5C (SM00515)  MA3 (SM00544)  MIF4G (SM00543)  
DMDM Disease mutations8672
Blocks (Seattle)O43432
PDB (SRS)1HU3   
PDB (PDBSum)1HU3   
PDB (IMB)1HU3   
PDB (RSDB)1HU3   
Human Protein AtlasENSG00000075151 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasO43432
HPRD06802
IPIIPI00646377   IPI00889701   IPI01014648   IPI01015386   IPI01010928   IPI00328268   IPI00979291   IPI00411710   IPI00514035   IPI00513762   
Protein Interaction databases
DIP (DOE-UCLA)O43432
IntAct (EBI)O43432
FunCoupENSG00000075151
BioGRIDEIF4G3
InParanoidO43432
Interologous Interaction database O43432
IntegromeDBEIF4G3
STRING (EMBL)EIF4G3
Ontologies - Pathways
Ontology : AmiGORNA cap binding  positive regulation of protein phosphorylation  translation initiation factor activity  cytosol  translational initiation  regulation of translational initiation  spermatogenesis  translation factor activity, nucleic acid binding  viral process  eukaryotic translation initiation factor 4F complex  cytokine-mediated signaling pathway  poly(A) RNA binding  positive regulation of translation  positive regulation of meiosis I  
Ontology : EGO-EBIRNA cap binding  positive regulation of protein phosphorylation  translation initiation factor activity  cytosol  translational initiation  regulation of translational initiation  spermatogenesis  translation factor activity, nucleic acid binding  viral process  eukaryotic translation initiation factor 4F complex  cytokine-mediated signaling pathway  poly(A) RNA binding  positive regulation of translation  positive regulation of meiosis I  
Pathways : BIOCARTARegulation of eIF4e and p70 S6 Kinase [Genes]    Eukaryotic protein translation [Genes]    mTOR Signaling Pathway [Genes]    Internal Ribosome entry pathway [Genes]   
Pathways : KEGGRNA transport    Viral myocarditis   
Protein Interaction DatabaseEIF4G3
Wikipedia pathwaysEIF4G3
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)EIF4G3
snp3D : Map Gene to Disease8672
SNP (GeneSNP Utah)EIF4G3
SNP : HGBaseEIF4G3
Genetic variants : HAPMAPEIF4G3
Exome VariantEIF4G3
1000_GenomesEIF4G3 
ICGC programENSG00000075151 
Somatic Mutations in Cancer : COSMICEIF4G3 
CONAN: Copy Number AnalysisEIF4G3 
Mutations and Diseases : HGMDEIF4G3
Mutations and Diseases : intOGenEIF4G3
Genomic VariantsEIF4G3  EIF4G3 [DGVbeta]
dbVarEIF4G3
ClinVarEIF4G3
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM603929   
MedgenEIF4G3
GENETestsEIF4G3
Disease Genetic AssociationEIF4G3
Huge Navigator EIF4G3 [HugePedia]  EIF4G3 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneEIF4G3
Homology/Alignments : Family Browser (UCSC)EIF4G3
Phylogenetic Trees/Animal Genes : TreeFamEIF4G3
Chemical/Protein Interactions : CTD8672
Chemical/Pharm GKB GenePA27724
Clinical trialEIF4G3
Cancer Resource (Charite)ENSG00000075151
Other databases
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
CoreMineEIF4G3
iHOPEIF4G3
OncoSearchEIF4G3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 16:45:38 CEST 2014

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