Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

EIF5AL1 (eukaryotic translation initiation factor 5A-like 1)

Identity

Alias_namesEIF5AP1
eukaryotic translation initiation factor 5A pseudogene 1
Alias_symbol (synonym)bA342M3.3
Other alias
HGNC (Hugo) EIF5AL1
LocusID (NCBI) 143244
Atlas_Id 62787
Location 10q22.3  [Link to chromosome band 10q22]
Location_base_pair Starts at 79512601 and ends at 79516436 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EIF5AL1   17419
Cards
Entrez_Gene (NCBI)EIF5AL1  143244  eukaryotic translation initiation factor 5A-like 1
AliasesEIF5AP1; bA342M3.3
GeneCards (Weizmann)EIF5AL1
Ensembl hg19 (Hinxton)ENSG00000253626 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000253626 [Gene_View]  chr10:79512601-79516436 [Contig_View]  EIF5AL1 [Vega]
ICGC DataPortalENSG00000253626
TCGA cBioPortalEIF5AL1
AceView (NCBI)EIF5AL1
Genatlas (Paris)EIF5AL1
WikiGenes143244
SOURCE (Princeton)EIF5AL1
Genetics Home Reference (NIH)EIF5AL1
Genomic and cartography
GoldenPath hg38 (UCSC)EIF5AL1  -     chr10:79512601-79516436 +  10q22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EIF5AL1  -     10q22.3   [Description]    (hg19-Feb_2009)
EnsemblEIF5AL1 - 10q22.3 [CytoView hg19]  EIF5AL1 - 10q22.3 [CytoView hg38]
Mapping of homologs : NCBIEIF5AL1 [Mapview hg19]  EIF5AL1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)BC070048
RefSeq transcript (Entrez)NM_001099692
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EIF5AL1
Cluster EST : UnigeneHs.104825 [ NCBI ]
CGAP (NCI)Hs.104825
Alternative Splicing GalleryENSG00000253626
Gene ExpressionEIF5AL1 [ NCBI-GEO ]   EIF5AL1 [ EBI - ARRAY_EXPRESS ]   EIF5AL1 [ SEEK ]   EIF5AL1 [ MEM ]
Gene Expression Viewer (FireBrowse)EIF5AL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)143244
GTEX Portal (Tissue expression)EIF5AL1
Human Protein AtlasENSG00000253626-EIF5AL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6IS14   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6IS14  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6IS14
Splice isoforms : SwissVarQ6IS14
PhosPhoSitePlusQ6IS14
Domaine pattern : Prosite (Expaxy)IF5A_HYPUSINE (PS00302)   
Domains : Interpro (EBI)NA-bd_OB-fold    Rib_L2_dom2    Trans_elong_IF5A_hypusine_site    Transl_elong_IF5A    Transl_elong_IF5A_C    Translation_prot_SH3-like   
Domain families : Pfam (Sanger)eIF-5a (PF01287)   
Domain families : Pfam (NCBI)pfam01287   
Domain families : Smart (EMBL)eIF-5a (SM01376)  
Conserved Domain (NCBI)EIF5AL1
DMDM Disease mutations143244
Blocks (Seattle)EIF5AL1
SuperfamilyQ6IS14
Human Protein Atlas [tissue]ENSG00000253626-EIF5AL1 [tissue]
Peptide AtlasQ6IS14
IPIIPI00855924   
Protein Interaction databases
DIP (DOE-UCLA)Q6IS14
IntAct (EBI)Q6IS14
FunCoupENSG00000253626
BioGRIDEIF5AL1
STRING (EMBL)EIF5AL1
ZODIACEIF5AL1
Ontologies - Pathways
QuickGOQ6IS14
Ontology : AmiGOtranslation elongation factor activity  nuclear pore  endoplasmic reticulum membrane  translational frameshifting  positive regulation of cytosolic calcium ion concentration  aging  positive regulation of cardiac muscle cell apoptotic process  protein transport  dendrite  ribosome binding  neuronal cell body  negative regulation of apoptotic process  positive regulation of translational elongation  positive regulation of translational termination  mRNA transport  positive regulation of muscle cell differentiation  cellular response to thyroid hormone stimulus  positive regulation of reactive oxygen species metabolic process  
Ontology : EGO-EBItranslation elongation factor activity  nuclear pore  endoplasmic reticulum membrane  translational frameshifting  positive regulation of cytosolic calcium ion concentration  aging  positive regulation of cardiac muscle cell apoptotic process  protein transport  dendrite  ribosome binding  neuronal cell body  negative regulation of apoptotic process  positive regulation of translational elongation  positive regulation of translational termination  mRNA transport  positive regulation of muscle cell differentiation  cellular response to thyroid hormone stimulus  positive regulation of reactive oxygen species metabolic process  
NDEx NetworkEIF5AL1
Atlas of Cancer Signalling NetworkEIF5AL1
Wikipedia pathwaysEIF5AL1
Orthology - Evolution
OrthoDB143244
GeneTree (enSembl)ENSG00000253626
Phylogenetic Trees/Animal Genes : TreeFamEIF5AL1
HOVERGENQ6IS14
HOGENOMQ6IS14
Homologs : HomoloGeneEIF5AL1
Homology/Alignments : Family Browser (UCSC)EIF5AL1
Gene fusions - Rearrangements
Tumor Fusion PortalEIF5AL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEIF5AL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EIF5AL1
dbVarEIF5AL1
ClinVarEIF5AL1
1000_GenomesEIF5AL1 
Exome Variant ServerEIF5AL1
ExAC (Exome Aggregation Consortium)ENSG00000253626
GNOMAD BrowserENSG00000253626
Genetic variants : HAPMAP143244
Genomic Variants (DGV)EIF5AL1 [DGVbeta]
DECIPHEREIF5AL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEIF5AL1 
Mutations
ICGC Data PortalEIF5AL1 
TCGA Data PortalEIF5AL1 
Broad Tumor PortalEIF5AL1
OASIS PortalEIF5AL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEIF5AL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEIF5AL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EIF5AL1
DgiDB (Drug Gene Interaction Database)EIF5AL1
DoCM (Curated mutations)EIF5AL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EIF5AL1 (select a term)
intoGenEIF5AL1
Cancer3DEIF5AL1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETEIF5AL1
MedgenEIF5AL1
Genetic Testing Registry EIF5AL1
NextProtQ6IS14 [Medical]
TSGene143244
GENETestsEIF5AL1
Target ValidationEIF5AL1
Huge Navigator EIF5AL1 [HugePedia]
snp3D : Map Gene to Disease143244
BioCentury BCIQEIF5AL1
ClinGenEIF5AL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD143244
Chemical/Pharm GKB GenePA134920977
Clinical trialEIF5AL1
Miscellaneous
canSAR (ICR)EIF5AL1 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEIF5AL1
EVEXEIF5AL1
GoPubMedEIF5AL1
iHOPEIF5AL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:21:29 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.