ELAVL2 (ELAV like RNA binding protein 2)

2008-10-01  

Identity

HGNC
LOCATION
9p21.3
LOCUSID
ALIAS
HEL-N1,HELN1,HUB
FUSION GENES

Other Information

Locus ID:

NCBI: 1993
MIM: 601673
HGNC: 3313
Ensembl: ENSG00000107105

Variants:

dbSNP: 1993
ClinVar: 1993
TCGA: ENSG00000107105
COSMIC: ELAVL2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000107105ENST00000223951Q12926
ENSG00000107105ENST00000380110A0A0A0MRX1
ENSG00000107105ENST00000380117Q12926
ENSG00000107105ENST00000397312Q12926
ENSG00000107105ENST00000423281C9JB16
ENSG00000107105ENST00000440102B1AM48
ENSG00000107105ENST00000544538Q12926

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
156710362005Involvement of Hu and heterogeneous nuclear ribonucleoprotein K in neuronal differentiation through p21 mRNA post-transcriptional regulation.41
235121052013Confirming genes influencing risk to cleft lip with/without cleft palate in a case-parent trio study.39
272604042016ELAVL2-regulated transcriptional and splicing networks in human neurons link neurodevelopment and autism.12
186070642008Molecular detection of neuron-specific ELAV-like-positive cells in the peripheral blood of patients with small-cell lung cancer.6
263664172015Systematic Analysis of Endometrial Cancer-Associated Hub Proteins Based on Text Mining.4
208187222010A Bayesian approach to genetic association studies with family-based designs.2
313583212019The neural ELAVL protein HuB enhances endogenous proto-oncogene activation.1

Citation

Dessen P

ELAVL2 (ELAV like RNA binding protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2008-10-01

Online version: http://atlasgeneticsoncology.org/gene/50396/elavl2