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ELF2 (E74-like factor 2 (ets domain transcription factor))

Identity

Other namesEU32
NERF
NERF-1A
NERF-1B
NERF-1a,b
NERF-2
HGNC (Hugo) ELF2
LocusID (NCBI) 1998
Atlas_Id 46993
Location 4q31.1
Location_base_pair Starts at 139978871 and ends at 140005568 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ELF2   3317
Cards
Entrez_Gene (NCBI)ELF2  1998  E74-like factor 2 (ets domain transcription factor)
GeneCards (Weizmann)ELF2
Ensembl hg19 (Hinxton)ENSG00000109381 [Gene_View]  chr4:139978871-140005568 [Contig_View]  ELF2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000109381 [Gene_View]  chr4:139978871-140005568 [Contig_View]  ELF2 [Vega]
ICGC DataPortalENSG00000109381
TCGA cBioPortalELF2
AceView (NCBI)ELF2
Genatlas (Paris)ELF2
WikiGenes1998
SOURCE (Princeton)ELF2
Genomic and cartography
GoldenPath hg19 (UCSC)ELF2  -     chr4:139978871-140005568 -  4q31.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ELF2  -     4q31.1   [Description]    (hg38-Dec_2013)
EnsemblELF2 - 4q31.1 [CytoView hg19]  ELF2 - 4q31.1 [CytoView hg38]
Mapping of homologs : NCBIELF2 [Mapview hg19]  ELF2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF256222 AF256223 AK301307 AK303782 AK316455
RefSeq transcript (Entrez)NM_001276457 NM_001276458 NM_001276459 NM_006874 NM_201999
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_016354 NW_004929320
Consensus coding sequences : CCDS (NCBI)ELF2
Cluster EST : UnigeneHs.634040 [ NCBI ]
CGAP (NCI)Hs.634040
Alternative Splicing : Fast-db (Paris)GSHG0023529
Alternative Splicing GalleryENSG00000109381
Gene ExpressionELF2 [ NCBI-GEO ]     ELF2 [ SEEK ]   ELF2 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15723 (Uniprot)
NextProtQ15723  [Medical]
With graphics : InterProQ15723
Splice isoforms : SwissVarQ15723 (Swissvar)
Domaine pattern : Prosite (Expaxy)ETS_DOMAIN_1 (PS00345)    ETS_DOMAIN_2 (PS00346)    ETS_DOMAIN_3 (PS50061)   
Domains : Interpro (EBI)Ets_dom    TF_Elf_N    WHTH_DNA-bd_dom   
Related proteins : CluSTrQ15723
Domain families : Pfam (Sanger)Elf-1_N (PF12310)    Ets (PF00178)   
Domain families : Pfam (NCBI)pfam12310    pfam00178   
Domain families : Smart (EMBL)ETS (SM00413)  
DMDM Disease mutations1998
Blocks (Seattle)Q15723
Human Protein AtlasENSG00000109381
Peptide AtlasQ15723
HPRD16856
IPIIPI00009995   IPI00607896   IPI00396265   IPI00607557   IPI00887863   IPI00439925   IPI00966545   IPI00967762   
Protein Interaction databases
DIP (DOE-UCLA)Q15723
IntAct (EBI)Q15723
FunCoupENSG00000109381
BioGRIDELF2
IntegromeDBELF2
STRING (EMBL)ELF2
Ontologies - Pathways
QuickGOQ15723
Ontology : AmiGOsequence-specific DNA binding RNA polymerase II transcription factor activity  sequence-specific DNA binding transcription factor activity  protein binding  nucleus  nucleoplasm  cytoplasm  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  cell differentiation  sequence-specific DNA binding  sequence-specific DNA binding  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  
Ontology : EGO-EBIsequence-specific DNA binding RNA polymerase II transcription factor activity  sequence-specific DNA binding transcription factor activity  protein binding  nucleus  nucleoplasm  cytoplasm  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  cell differentiation  sequence-specific DNA binding  sequence-specific DNA binding  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  
Protein Interaction DatabaseELF2
DoCM (Curated mutations)ELF2
Wikipedia pathwaysELF2
Gene fusion - Rearrangements
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerELF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ELF2
dbVarELF2
ClinVarELF2
1000_GenomesELF2 
Exome Variant ServerELF2
SNP (GeneSNP Utah)ELF2
SNP : HGBaseELF2
Genetic variants : HAPMAPELF2
Genomic Variants (DGV)ELF2 [DGVbeta]
Mutations
ICGC Data PortalELF2 
TCGA Data PortalELF2 
Tumor PortalELF2
Somatic Mutations in Cancer : COSMICELF2 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)4:139978871-140005568
CONAN: Copy Number AnalysisELF2 
Mutations and Diseases : HGMDELF2
OMIM
MedgenELF2
NextProtQ15723 [Medical]
GENETestsELF2
Disease Genetic AssociationELF2
Huge Navigator ELF2 [HugePedia]  ELF2 [HugeCancerGEM]
snp3D : Map Gene to Disease1998
DGIdb (Drug Gene Interaction db)ELF2
General knowledge
Homologs : HomoloGeneELF2
Homology/Alignments : Family Browser (UCSC)ELF2
Phylogenetic Trees/Animal Genes : TreeFamELF2
Chemical/Protein Interactions : CTD1998
Chemical/Pharm GKB GenePA27745
Clinical trialELF2
Cancer Resource (Charite)ENSG00000109381
Other databases
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
CoreMineELF2
GoPubMedELF2
iHOPELF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Apr 13 14:22:31 CEST 2015

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