Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret
Donations are also welcome

Donate (in Euros)

Donate (in US Dollars)


ELF3 (E74-like factor 3 (ets domain transcription factor, epithelial-specific ))

Identity

Other namesEPR-1
ERT
ESE-1
ESX
HGNC (Hugo) ELF3
LocusID (NCBI) 1999
Location 1q32.1
Location_base_pair Starts at 201979690 and ends at 201986315 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ELF3   3318
Cards
Entrez_Gene (NCBI)ELF3  1999  E74-like factor 3 (ets domain transcription factor, epithelial-specific )
GeneCards (Weizmann)ELF3
Ensembl hg19 (Hinxton)ENSG00000163435 [Gene_View]  chr1:201979690-201986315 [Contig_View]  ELF3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000163435 [Gene_View]  chr1:201979690-201986315 [Contig_View]  ELF3 [Vega]
ICGC DataPortalENSG00000163435
cBioPortalELF3
AceView (NCBI)ELF3
Genatlas (Paris)ELF3
WikiGenes1999
SOURCE (Princeton)ELF3
Genomic and cartography
GoldenPath hg19 (UCSC)ELF3  -     chr1:201979690-201986315 +  1q32.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ELF3  -     1q32.1   [Description]    (hg38-Dec_2013)
EnsemblELF3 - 1q32.1 [CytoView hg19]  ELF3 - 1q32.1 [CytoView hg38]
Mapping of homologs : NCBIELF3 [Mapview hg19]  ELF3 [Mapview hg38]
OMIM602191   
Gene and transcription
Genbank (Entrez)AF016295 AF017307 AF517841 AK225446 AK309265
RefSeq transcript (Entrez)NM_001114309 NM_004433
RefSeq genomic (Entrez)AC_000133 NC_000001 NC_018912 NT_004487 NW_001838533 NW_004929293
Consensus coding sequences : CCDS (NCBI)ELF3
Cluster EST : UnigeneHs.603657 [ NCBI ]
CGAP (NCI)Hs.603657
Alternative Splicing : Fast-db (Paris)GSHG0001333
Alternative Splicing GalleryENSG00000163435
Gene ExpressionELF3 [ NCBI-GEO ]     ELF3 [ SEEK ]   ELF3 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP78545 (Uniprot)
NextProtP78545  [Medical]
With graphics : InterProP78545
Splice isoforms : SwissVarP78545 (Swissvar)
Domaine pattern : Prosite (Expaxy)ETS_DOMAIN_3 (PS50061)    PNT (PS51433)   
Domains : Interpro (EBI)AT_hook_DNA-bd_motif    Ets_dom    Pointed_dom    SAM/pointed    WHTH_DNA-bd_dom   
Related proteins : CluSTrP78545
Domain families : Pfam (Sanger)Ets (PF00178)    SAM_PNT (PF02198)   
Domain families : Pfam (NCBI)pfam00178    pfam02198   
Domain families : Smart (EMBL)AT_hook (SM00384)  ETS (SM00413)  SAM_PNT (SM00251)  
DMDM Disease mutations1999
Blocks (Seattle)P78545
PDB (SRS)2E8P   
PDB (PDBSum)2E8P   
PDB (IMB)2E8P   
PDB (RSDB)2E8P   
Human Protein AtlasENSG00000163435
Peptide AtlasP78545
HPRD03722
IPIIPI00004581   IPI00844532   IPI00984618   IPI00643579   
Protein Interaction databases
DIP (DOE-UCLA)P78545
IntAct (EBI)P78545
FunCoupENSG00000163435
BioGRIDELF3
IntegromeDBELF3
STRING (EMBL)ELF3
Ontologies - Pathways
QuickGOP78545
Ontology : AmiGOsequence-specific DNA binding RNA polymerase II transcription factor activity  blastocyst development  sequence-specific DNA binding transcription factor activity  transcription coactivator activity  protein binding  nucleus  cytoplasm  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  inflammatory response  multicellular organismal development  epidermis development  extracellular matrix organization  epithelial cell differentiation  sequence-specific DNA binding  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  mammary gland involution  
Ontology : EGO-EBIsequence-specific DNA binding RNA polymerase II transcription factor activity  blastocyst development  sequence-specific DNA binding transcription factor activity  transcription coactivator activity  protein binding  nucleus  cytoplasm  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  inflammatory response  multicellular organismal development  epidermis development  extracellular matrix organization  epithelial cell differentiation  sequence-specific DNA binding  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  mammary gland involution  
Protein Interaction DatabaseELF3
DoCM (Curated mutations)ELF3
Wikipedia pathwaysELF3
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerELF3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ELF3
dbVarELF3
ClinVarELF3
1000_GenomesELF3 
Exome Variant ServerELF3
SNP (GeneSNP Utah)ELF3
SNP : HGBaseELF3
Genetic variants : HAPMAPELF3
Genomic Variants (DGV)ELF3 [DGVbeta]
Mutations
ICGC Data PortalENSG00000163435 
Somatic Mutations in Cancer : COSMICELF3 
CONAN: Copy Number AnalysisELF3 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)1:201979690-201986315
Mutations and Diseases : HGMDELF3
OMIM602191   
MedgenELF3
NextProtP78545 [Medical]
GENETestsELF3
Disease Genetic AssociationELF3
Huge Navigator ELF3 [HugePedia]  ELF3 [HugeCancerGEM]
snp3D : Map Gene to Disease1999
DGIdb (Drug Gene Interaction db)ELF3
General knowledge
Homologs : HomoloGeneELF3
Homology/Alignments : Family Browser (UCSC)ELF3
Phylogenetic Trees/Animal Genes : TreeFamELF3
Chemical/Protein Interactions : CTD1999
Chemical/Pharm GKB GenePA27746
Clinical trialELF3
Cancer Resource (Charite)ENSG00000163435
Other databases
Probes
Litterature
PubMed48 Pubmed reference(s) in Entrez
CoreMineELF3
GoPubMedELF3
iHOPELF3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 14 15:36:56 CET 2015

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.