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ELF3 (E74 like ETS transcription factor 3)

Identity

Other namesEPR-1
ERT
ESE-1
ESX
HGNC (Hugo) ELF3
LocusID (NCBI) 1999
Atlas_Id 40439
Location 1q32.1
Location_base_pair Starts at 201979690 and ends at 201986315 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CNOT1 (16q21) / ELF3 (1q32.1)ELF3 (1q32.1) / ELF3 (1q32.1)ELF3 (1q32.1) / RPL39 (Xq24)
ELF3 (1q32.1) / SLC39A6 (18q12.2)GNB1 (1p36.33) / ELF3 (1q32.1)KALRN (3q21.2) / ELF3 (1q32.1)
LOC100507412 (-) / ELF3 (1q32.1)RPL21 (13q12.2) / ELF3 (1q32.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ELF3   3318
Cards
Entrez_Gene (NCBI)ELF3  1999  E74 like ETS transcription factor 3
GeneCards (Weizmann)ELF3
Ensembl hg19 (Hinxton)ENSG00000163435 [Gene_View]  chr1:201979690-201986315 [Contig_View]  ELF3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000163435 [Gene_View]  chr1:201979690-201986315 [Contig_View]  ELF3 [Vega]
ICGC DataPortalENSG00000163435
TCGA cBioPortalELF3
AceView (NCBI)ELF3
Genatlas (Paris)ELF3
WikiGenes1999
SOURCE (Princeton)ELF3
Genomic and cartography
GoldenPath hg19 (UCSC)ELF3  -     chr1:201979690-201986315 +  1q32.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ELF3  -     1q32.1   [Description]    (hg38-Dec_2013)
EnsemblELF3 - 1q32.1 [CytoView hg19]  ELF3 - 1q32.1 [CytoView hg38]
Mapping of homologs : NCBIELF3 [Mapview hg19]  ELF3 [Mapview hg38]
OMIM602191   
Gene and transcription
Genbank (Entrez)AF016295 AF017307 AF517841 AK225446 AK309265
RefSeq transcript (Entrez)NM_001114309 NM_004433
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)ELF3
Cluster EST : UnigeneHs.603657 [ NCBI ]
CGAP (NCI)Hs.603657
Alternative Splicing : Fast-db (Paris)GSHG0001333
Alternative Splicing GalleryENSG00000163435
Gene ExpressionELF3 [ NCBI-GEO ]   ELF3 [ EBI - ARRAY_EXPRESS ]   ELF3 [ SEEK ]   ELF3 [ MEM ]
Gene Expression Viewer (FireBrowse)ELF3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)1999
Protein : pattern, domain, 3D structure
UniProt/SwissProtP78545 (Uniprot)
NextProtP78545  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP78545
Splice isoforms : SwissVarP78545 (Swissvar)
PhosPhoSitePlusP78545
Domaine pattern : Prosite (Expaxy)ETS_DOMAIN_3 (PS50061)    PNT (PS51433)   
Domains : Interpro (EBI)AT_hook_DNA-bd_motif    Ets_dom    Pointed_dom    SAM/pointed    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)Ets (PF00178)    SAM_PNT (PF02198)   
Domain families : Pfam (NCBI)pfam00178    pfam02198   
Domain families : Smart (EMBL)AT_hook (SM00384)  ETS (SM00413)  SAM_PNT (SM00251)  
DMDM Disease mutations1999
Blocks (Seattle)ELF3
PDB (SRS)2E8P   
PDB (PDBSum)2E8P   
PDB (IMB)2E8P   
PDB (RSDB)2E8P   
Structural Biology KnowledgeBase2E8P   
SCOP (Structural Classification of Proteins)2E8P   
CATH (Classification of proteins structures)2E8P   
SuperfamilyP78545
Human Protein AtlasENSG00000163435
Peptide AtlasP78545
HPRD03722
IPIIPI00004581   IPI00844532   IPI00984618   IPI00643579   
Protein Interaction databases
DIP (DOE-UCLA)P78545
IntAct (EBI)P78545
FunCoupENSG00000163435
BioGRIDELF3
STRING (EMBL)ELF3
ZODIACELF3
Ontologies - Pathways
QuickGOP78545
Ontology : AmiGORNA polymerase II core promoter proximal region sequence-specific DNA binding  RNA polymerase II transcription factor activity, sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  blastocyst development  transcription factor activity, sequence-specific DNA binding  transcription coactivator activity  protein binding  nucleus  nucleus  cytoplasm  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  inflammatory response  multicellular organism development  epidermis development  extracellular matrix organization  epithelial cell differentiation  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  mammary gland involution  
Ontology : EGO-EBIRNA polymerase II core promoter proximal region sequence-specific DNA binding  RNA polymerase II transcription factor activity, sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  blastocyst development  transcription factor activity, sequence-specific DNA binding  transcription coactivator activity  protein binding  nucleus  nucleus  cytoplasm  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  inflammatory response  multicellular organism development  epidermis development  extracellular matrix organization  epithelial cell differentiation  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  mammary gland involution  
NDEx Network
Atlas of Cancer Signalling NetworkELF3
Wikipedia pathwaysELF3
Orthology - Evolution
OrthoDB1999
GeneTree (enSembl)ENSG00000163435
Phylogenetic Trees/Animal Genes : TreeFamELF3
Homologs : HomoloGeneELF3
Homology/Alignments : Family Browser (UCSC)ELF3
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerELF3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ELF3
dbVarELF3
ClinVarELF3
1000_GenomesELF3 
Exome Variant ServerELF3
ExAC (Exome Aggregation Consortium)ELF3 (select the gene name)
SNP (GeneSNP Utah)ELF3
SNP : HGBaseELF3
Genetic variants : HAPMAPELF3
Genomic Variants (DGV)ELF3 [DGVbeta]
Mutations
ICGC Data PortalELF3 
TCGA Data PortalELF3 
Broad Tumor PortalELF3
OASIS PortalELF3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICELF3 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ELF3
DgiDB (Drug Gene Interaction Database)ELF3
DoCM (Curated mutations)ELF3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ELF3 (select a term)
intoGenELF3
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)1:201979690-201986315
CONAN: Copy Number AnalysisELF3 
Mutations and Diseases : HGMDELF3
OMIM602191   
MedgenELF3
Genetic Testing Registry ELF3
NextProtP78545 [Medical]
TSGene1999
GENETestsELF3
Huge Navigator ELF3 [HugePedia]  ELF3 [HugeCancerGEM]
snp3D : Map Gene to Disease1999
BioCentury BCIQELF3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1999
Chemical/Pharm GKB GenePA27746
Clinical trialELF3
Miscellaneous
canSAR (ICR)ELF3 (select the gene name)
Probes
Litterature
PubMed53 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineELF3
GoPubMedELF3
iHOPELF3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Apr 16 17:43:39 CEST 2016

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