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ELFN2 (extracellular leucine rich repeat and fibronectin type III domain containing 2)

Identity

Alias_namesLRRC62
PPP1R29
leucine rich repeat containing 62
extracellular leucine-rich repeat and fibronectin type III containing 2
protein phosphatase 1, regulatory subunit 29
Alias_symbol (synonym)dJ63G5.3
KIAA1904
Other alias
HGNC (Hugo) ELFN2
LocusID (NCBI) 114794
Atlas_Id 62793
Location 22q13.1  [Link to chromosome band 22q13]
Location_base_pair Starts at 37367960 and ends at 37427470 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ELFN2   29396
Cards
Entrez_Gene (NCBI)ELFN2  114794  extracellular leucine rich repeat and fibronectin type III domain containing 2
AliasesLRRC62; PPP1R29
GeneCards (Weizmann)ELFN2
Ensembl hg19 (Hinxton)ENSG00000166897 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166897 [Gene_View]  chr22:37367960-37427470 [Contig_View]  ELFN2 [Vega]
ICGC DataPortalENSG00000166897
TCGA cBioPortalELFN2
AceView (NCBI)ELFN2
Genatlas (Paris)ELFN2
WikiGenes114794
SOURCE (Princeton)ELFN2
Genetics Home Reference (NIH)ELFN2
Genomic and cartography
GoldenPath hg38 (UCSC)ELFN2  -     chr22:37367960-37427470 -  22q13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ELFN2  -     22q13.1   [Description]    (hg19-Feb_2009)
EnsemblELFN2 - 22q13.1 [CytoView hg19]  ELFN2 - 22q13.1 [CytoView hg38]
Mapping of homologs : NCBIELFN2 [Mapview hg19]  ELFN2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB067491 AK055475 BC032082 BC032083 BC041596
RefSeq transcript (Entrez)NM_052906
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ELFN2
Cluster EST : UnigeneHs.660812 [ NCBI ]
CGAP (NCI)Hs.660812
Alternative Splicing GalleryENSG00000166897
Gene ExpressionELFN2 [ NCBI-GEO ]   ELFN2 [ EBI - ARRAY_EXPRESS ]   ELFN2 [ SEEK ]   ELFN2 [ MEM ]
Gene Expression Viewer (FireBrowse)ELFN2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)114794
GTEX Portal (Tissue expression)ELFN2
Human Protein AtlasENSG00000166897-ELFN2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5R3F8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5R3F8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5R3F8
Splice isoforms : SwissVarQ5R3F8
PhosPhoSitePlusQ5R3F8
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp   
Domain families : Pfam (Sanger)LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam13855   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  
Conserved Domain (NCBI)ELFN2
DMDM Disease mutations114794
Blocks (Seattle)ELFN2
SuperfamilyQ5R3F8
Human Protein Atlas [tissue]ENSG00000166897-ELFN2 [tissue]
Peptide AtlasQ5R3F8
HPRD17229
IPIIPI00289849   IPI00984098   
Protein Interaction databases
DIP (DOE-UCLA)Q5R3F8
IntAct (EBI)Q5R3F8
FunCoupENSG00000166897
BioGRIDELFN2
STRING (EMBL)ELFN2
ZODIACELFN2
Ontologies - Pathways
QuickGOQ5R3F8
Ontology : AmiGOprotein phosphatase inhibitor activity  extracellular space  negative regulation of phosphatase activity  integral component of membrane  phosphatase binding  
Ontology : EGO-EBIprotein phosphatase inhibitor activity  extracellular space  negative regulation of phosphatase activity  integral component of membrane  phosphatase binding  
NDEx NetworkELFN2
Atlas of Cancer Signalling NetworkELFN2
Wikipedia pathwaysELFN2
Orthology - Evolution
OrthoDB114794
GeneTree (enSembl)ENSG00000166897
Phylogenetic Trees/Animal Genes : TreeFamELFN2
HOVERGENQ5R3F8
HOGENOMQ5R3F8
Homologs : HomoloGeneELFN2
Homology/Alignments : Family Browser (UCSC)ELFN2
Gene fusions - Rearrangements
Tumor Fusion PortalELFN2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerELFN2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ELFN2
dbVarELFN2
ClinVarELFN2
1000_GenomesELFN2 
Exome Variant ServerELFN2
ExAC (Exome Aggregation Consortium)ENSG00000166897
GNOMAD BrowserENSG00000166897
Genetic variants : HAPMAP114794
Genomic Variants (DGV)ELFN2 [DGVbeta]
DECIPHERELFN2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisELFN2 
Mutations
ICGC Data PortalELFN2 
TCGA Data PortalELFN2 
Broad Tumor PortalELFN2
OASIS PortalELFN2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICELFN2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDELFN2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ELFN2
DgiDB (Drug Gene Interaction Database)ELFN2
DoCM (Curated mutations)ELFN2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ELFN2 (select a term)
intoGenELFN2
Cancer3DELFN2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETELFN2
MedgenELFN2
Genetic Testing Registry ELFN2
NextProtQ5R3F8 [Medical]
TSGene114794
GENETestsELFN2
Target ValidationELFN2
Huge Navigator ELFN2 [HugePedia]
snp3D : Map Gene to Disease114794
BioCentury BCIQELFN2
ClinGenELFN2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD114794
Chemical/Pharm GKB GenePA162385040
Clinical trialELFN2
Miscellaneous
canSAR (ICR)ELFN2 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineELFN2
EVEXELFN2
GoPubMedELFN2
iHOPELFN2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:43:37 CET 2017

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