| Nomenclature |
|---|
| HGNC (Hugo) | ELK1 3321 |
| Cards |
|---|
| Entrez_Gene (NCBI) | ELK1 ETS transcription factor ELK1 |
| Aliases | |
| GeneCards (Weizmann) | ELK1 |
| Ensembl hg19 (Hinxton) | ENSG00000126767 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000126767 [Gene_View] ENSG00000126767 [Sequence] chrX:47635520-47650604 [Contig_View] ELK1 [Vega] |
| ICGC DataPortal | ENSG00000126767 |
| TCGA cBioPortal | ELK1 |
| AceView (NCBI) | ELK1 |
| Genatlas (Paris) | ELK1 |
| SOURCE (Princeton) | ELK1 |
| Genetics Home Reference (NIH) | ELK1 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | ELK1 - chrX:47635520-47650604 - Xp11.23 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | ELK1 - Xp11.23 [Description] (hg19-Feb_2009) |
| GoldenPath | ELK1 - Xp11.23 [CytoView hg19] ELK1 - Xp11.23 [CytoView hg38] |
| ImmunoBase | ENSG00000126767 |
| Genome Data Viewer NCBI | ELK1 [Mapview hg19] |
| OMIM | 311040 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AB016193 AB209047 AF000672 AK093966 AK312984 |
| RefSeq transcript (Entrez) | NM_001114123 NM_001257168 NM_005229 |
| Consensus coding sequences : CCDS (NCBI) | ELK1 |
| Gene Expression | ELK1 [ NCBI-GEO ] ELK1 [ EBI - ARRAY_EXPRESS ]
ELK1 [ SEEK ] ELK1 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | ELK1 [ Firebrowse - Broad ] |
| Genevisible | Expression of ELK1 in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 2002 |
| GTEX Portal (Tissue expression) | ELK1 |
| Human Protein Atlas | ENSG00000126767-ELK1 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P19419 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P19419 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P19419 |
| PhosPhoSitePlus | P19419 |
| Domaine pattern : Prosite (Expaxy) | ETS_DOMAIN_1 (PS00345) ETS_DOMAIN_2 (PS00346) ETS_DOMAIN_3 (PS50061) |
| Domains : Interpro (EBI) | Ets_dom WH-like_DNA-bd_sf WH_DNA-bd_sf |
| Domain families : Pfam (Sanger) | Ets (PF00178) |
| Domain families : Pfam (NCBI) | pfam00178 |
| Domain families : Smart (EMBL) | ETS (SM00413) |
| Conserved Domain (NCBI) | ELK1 |
| PDB (RSDB) | 1DUX 5VVT |
| PDB Europe | 1DUX 5VVT |
| PDB (PDBSum) | 1DUX 5VVT |
| PDB (IMB) | 1DUX 5VVT |
| Structural Biology KnowledgeBase | 1DUX 5VVT |
| SCOP (Structural Classification of Proteins) | 1DUX 5VVT |
| CATH (Classification of proteins structures) | 1DUX 5VVT |
| Superfamily | P19419 |
| AlphaFold pdb e-kb | P19419 |
| Human Protein Atlas [tissue] | ENSG00000126767-ELK1 [tissue] |
| HPRD | 02407 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P19419 |
| IntAct (EBI) | P19419 |
| BioGRID | ELK1 |
| STRING (EMBL) | ELK1 |
| ZODIAC | ELK1 |
| Ontologies - Pathways |
|---|
| QuickGO | P19419 |
| Ontology : AmiGO | chromatin transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific liver development chromatin binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm mitochondrion regulation of transcription by RNA polymerase II response to light stimulus gene expression cell differentiation lung development nuclear receptor coactivator activity dendrite neuronal cell body axon terminus positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II RNA polymerase II-specific DNA-binding transcription factor binding cellular response to testosterone stimulus cellular response to gamma radiation response to fibroblast growth factor positive regulation of neuron death sequence-specific double-stranded DNA binding |
| Ontology : EGO-EBI | chromatin transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific liver development chromatin binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm mitochondrion regulation of transcription by RNA polymerase II response to light stimulus gene expression cell differentiation lung development nuclear receptor coactivator activity dendrite neuronal cell body axon terminus positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II RNA polymerase II-specific DNA-binding transcription factor binding cellular response to testosterone stimulus cellular response to gamma radiation response to fibroblast growth factor positive regulation of neuron death sequence-specific double-stranded DNA binding |
| Pathways : BIOCARTA | BIOCARTA_AT1RPATHWAY BIOCARTA_BCRPATHWAY BIOCARTA_EGFPATHWAY BIOCARTA_EPOPATHWAY BIOCARTA_ERKPATHWAY BIOCARTA_FCER1PATHWAY BIOCARTA_FMLPPATHWAY BIOCARTA_IGF1PATHWAY BIOCARTA_IL2PATHWAY BIOCARTA_IL6PATHWAY BIOCARTA_INSULINPATHWAY BIOCARTA_MAPKPATHWAY BIOCARTA_NGFPATHWAY BIOCARTA_P38MAPKPATHWAY BIOCARTA_PDGFPATHWAY BIOCARTA_RASPATHWAY BIOCARTA_METPATHWAY BIOCARTA_GPCRPATHWAY BIOCARTA_TCRPATHWAY BIOCARTA_TOLLPATHWAY |
| Pathways : KEGG | KEGG_MAPK_SIGNALING KEGG_ERBB_SIGNALING KEGG_FOCAL_ADHESION KEGG_INSULIN_SIGNALING KEGG_GNRH_SIGNALING KEGG_PRION_DISEASES KEGG_LEISHMANIA_INFECTION KEGG_ENDOMETRIAL_CANCER |
| NDEx Network | ELK1 |
| Atlas of Cancer Signalling Network | ELK1 |
| Wikipedia pathways | ELK1 |
| Orthology - Evolution |
|---|
| OrthoDB | 2002 |
| GeneTree (enSembl) | ENSG00000126767 |
| Phylogenetic Trees/Animal Genes : TreeFam | ELK1 |
| Homologs : HomoloGene | ELK1 |
| Homology/Alignments : Family Browser (UCSC) | ELK1 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | ELK1 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | ELK1 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | ELK1 |
| dbVar | ELK1 |
| ClinVar | ELK1 |
| Monarch | ELK1 |
| 1000_Genomes | ELK1 |
| Exome Variant Server | ELK1 |
| GNOMAD Browser | ENSG00000126767 |
| Varsome Browser | ELK1 |
| ACMG | ELK1 variants |
| Varity | P19419 |
| Genomic Variants (DGV) | ELK1 [DGVbeta] |
| DECIPHER | ELK1 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | ELK1 |
| Mutations |
|---|
| ICGC Data Portal | ELK1 |
| TCGA Data Portal | ELK1 |
| Broad Tumor Portal | ELK1 |
| OASIS Portal | ELK1 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | ELK1 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | ELK1 |
| Mutations and Diseases : HGMD | ELK1 |
| LOVD (Leiden Open Variation Database) | [gene] [transcripts] [variants] |
| BioMuta | ELK1 |
| DgiDB (Drug Gene Interaction Database) | ELK1 |
| DoCM (Curated mutations) | ELK1 |
| CIViC (Clinical Interpretations of Variants in Cancer) | ELK1 |
| Cancer3D | ELK1 |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 311040 |
| Orphanet | |
| DisGeNET | ELK1 |
| Medgen | ELK1 |
| Genetic Testing Registry | ELK1
|
| NextProt | P19419 [Medical] |
| GENETests | ELK1 |
| Target Validation | ELK1 |
| Huge Navigator |
ELK1 [HugePedia] |
| ClinGen | ELK1 (curated) |
| Clinical trials, drugs, therapy |
|---|
| MyCancerGenome | ELK1 |
| Protein Interactions : CTD | ELK1 |
| Pharm GKB Gene | PA27749 |
| Pharm GKB Pathways | PA162356267 |
| Pharos | P19419 |
| Clinical trial | ELK1 |
| Miscellaneous |
|---|
| canSAR (ICR) | ELK1 |
| Harmonizome | ELK1 |
| ARCHS4 | ELK1 |
| DataMed Index | ELK1 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 225 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| EVEX | ELK1 |
