| Nomenclature |
|---|
| HGNC (Hugo) | ELK1 3321 |
| Cards |
|---|
| Entrez_Gene (NCBI) | ELK1 2002 ELK1, ETS transcription factor |
| Aliases | |
| GeneCards (Weizmann) | ELK1 |
| Ensembl hg19 (Hinxton) | ENSG00000126767 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000126767 [Gene_View] ENSG00000126767 [Sequence] chrX:47635520-47650604 [Contig_View] ELK1 [Vega] |
| ICGC DataPortal | ENSG00000126767 |
| TCGA cBioPortal | ELK1 |
| AceView (NCBI) | ELK1 |
| Genatlas (Paris) | ELK1 |
| WikiGenes | 2002 |
| SOURCE (Princeton) | ELK1 |
| Genetics Home Reference (NIH) | ELK1 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | ELK1 - chrX:47635520-47650604 - Xp11.23 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | ELK1 - Xp11.23 [Description] (hg19-Feb_2009) |
| Ensembl | ELK1 - Xp11.23 [CytoView hg19] ELK1 - Xp11.23 [CytoView hg38] |
| Mapping of homologs : NCBI | ELK1 [Mapview hg19] ELK1 [Mapview hg38] |
| OMIM | 311040 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AB016193 AB209047 AF000672 AK093966 AK312984 |
| RefSeq transcript (Entrez) | NM_001114123 NM_001257168 NM_005229 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | ELK1 |
| Cluster EST : Unigene | Hs.740673 [ NCBI ] |
| CGAP (NCI) | Hs.740673 |
| Alternative Splicing Gallery | ENSG00000126767 |
| Gene Expression | ELK1 [ NCBI-GEO ] ELK1 [ EBI - ARRAY_EXPRESS ]
ELK1 [ SEEK ] ELK1 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | ELK1 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 2002 |
| GTEX Portal (Tissue expression) | ELK1 |
| Human Protein Atlas | ENSG00000126767-ELK1 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P19419 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P19419 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P19419 |
| Splice isoforms : SwissVar | P19419 |
| PhosPhoSitePlus | P19419 |
| Domaine pattern : Prosite (Expaxy) | ETS_DOMAIN_1 (PS00345) ETS_DOMAIN_2 (PS00346) ETS_DOMAIN_3 (PS50061) |
| Domains : Interpro (EBI) | Ets_dom WH-like_DNA-bd_sf WH_DNA-bd_sf |
| Domain families : Pfam (Sanger) | Ets (PF00178) |
| Domain families : Pfam (NCBI) | pfam00178 |
| Domain families : Smart (EMBL) | ETS (SM00413) |
| Conserved Domain (NCBI) | ELK1 |
| DMDM Disease mutations | 2002 |
| Blocks (Seattle) | ELK1 |
| PDB (SRS) | 1DUX 5VVT |
| PDB (PDBSum) | 1DUX 5VVT |
| PDB (IMB) | 1DUX 5VVT |
| PDB (RSDB) | 1DUX 5VVT |
| Structural Biology KnowledgeBase | 1DUX 5VVT |
| SCOP (Structural Classification of Proteins) | 1DUX 5VVT |
| CATH (Classification of proteins structures) | 1DUX 5VVT |
| Superfamily | P19419 |
| Human Protein Atlas [tissue] | ENSG00000126767-ELK1 [tissue] |
| Peptide Atlas | P19419 |
| HPRD | 02407 |
| IPI | IPI00301527 IPI00220075 IPI01012727 IPI01022186 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P19419 |
| IntAct (EBI) | P19419 |
| FunCoup | ENSG00000126767 |
| BioGRID | ELK1 |
| STRING (EMBL) | ELK1 |
| ZODIAC | ELK1 |
| Ontologies - Pathways |
|---|
| QuickGO | P19419 |
| Ontology : AmiGO | RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II transcription factor binding DNA-binding transcription activator activity, RNA polymerase II-specific chromatin binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm mitochondrion regulation of transcription by RNA polymerase II response to light stimulus cell differentiation dendrite neuronal cell body axon terminus positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II cellular response to testosterone stimulus cellular response to gamma radiation response to fibroblast growth factor positive regulation of neuron death |
| Ontology : EGO-EBI | RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II transcription factor binding DNA-binding transcription activator activity, RNA polymerase II-specific chromatin binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm mitochondrion regulation of transcription by RNA polymerase II response to light stimulus cell differentiation dendrite neuronal cell body axon terminus positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II cellular response to testosterone stimulus cellular response to gamma radiation response to fibroblast growth factor positive regulation of neuron death |
| Pathways : KEGG | MAPK signaling pathway ErbB signaling pathway Ras signaling pathway Focal adhesion Insulin signaling pathway GnRH signaling pathway Prion diseases Leishmaniasis Hepatitis B HTLV-I infection Proteoglycans in cancer Endometrial cancer |
| NDEx Network | ELK1 |
| Atlas of Cancer Signalling Network | ELK1 |
| Wikipedia pathways | ELK1 |
| Orthology - Evolution |
|---|
| OrthoDB | 2002 |
| GeneTree (enSembl) | ENSG00000126767 |
| Phylogenetic Trees/Animal Genes : TreeFam | ELK1 |
| HOGENOM | P19419 |
| Homologs : HomoloGene | ELK1 |
| Homology/Alignments : Family Browser (UCSC) | ELK1 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | ELK1 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | ELK1 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | ELK1 |
| dbVar | ELK1 |
| ClinVar | ELK1 |
| 1000_Genomes | ELK1 |
| Exome Variant Server | ELK1 |
| ExAC (Exome Aggregation Consortium) | ENSG00000126767 |
| GNOMAD Browser | ENSG00000126767 |
| Varsome Browser | ELK1 |
| Genetic variants : HAPMAP | 2002 |
| Genomic Variants (DGV) | ELK1 [DGVbeta] |
| DECIPHER | ELK1 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | ELK1 |
| Mutations |
|---|
| ICGC Data Portal | ELK1 |
| TCGA Data Portal | ELK1 |
| Broad Tumor Portal | ELK1 |
| OASIS Portal | ELK1 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | ELK1 [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | ELK1 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| LOVD (Leiden Open Variation Database) | X-chromosome gene database |
| BioMuta | search ELK1 |
| DgiDB (Drug Gene Interaction Database) | ELK1 |
| DoCM (Curated mutations) | ELK1 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | ELK1 (select a term) |
| intoGen | ELK1 |
| Cancer3D | ELK1(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 311040 |
| Orphanet | |
| DisGeNET | ELK1 |
| Medgen | ELK1 |
| Genetic Testing Registry | ELK1
|
| NextProt | P19419 [Medical] |
| TSGene | 2002 |
| GENETests | ELK1 |
| Target Validation | ELK1 |
| Huge Navigator |
ELK1 [HugePedia] |
| snp3D : Map Gene to Disease | 2002 |
| BioCentury BCIQ | ELK1 |
| ClinGen | ELK1 (curated) |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 2002 |
| Chemical/Pharm GKB Gene | PA27749 |
| Clinical trial | ELK1 |
| Miscellaneous |
|---|
| canSAR (ICR) | ELK1 (select the gene name) |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 188 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | ELK1 |
| EVEX | ELK1 |
| GoPubMed | ELK1 |
| iHOP | ELK1 |
