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ELMO2 (engulfment and cell motility 2)

Identity

Alias_namesengulfment and cell motility 2 (ced-12 homolog, C. elegans)
Alias_symbol (synonym)CED12
ELMO-2
CED-12
KIAA1834
FLJ11656
Other alias
HGNC (Hugo) ELMO2
LocusID (NCBI) 63916
Atlas_Id 62795
Location 20q13.12  [Link to chromosome band 20q13]
Location_base_pair Starts at 44994690 and ends at 45035271 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ELMO2 (20q13.12) / ELMO2 (20q13.12)ELMO2 (20q13.12) / RAE1 (20q13.31)ELMO2 (20q13.12) / STAP1 (4q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ELMO2   17233
Cards
Entrez_Gene (NCBI)ELMO2  63916  engulfment and cell motility 2
AliasesCED-12; CED12; ELMO-2
GeneCards (Weizmann)ELMO2
Ensembl hg19 (Hinxton)ENSG00000062598 [Gene_View]  chr20:44994690-45035271 [Contig_View]  ELMO2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000062598 [Gene_View]  chr20:44994690-45035271 [Contig_View]  ELMO2 [Vega]
ICGC DataPortalENSG00000062598
TCGA cBioPortalELMO2
AceView (NCBI)ELMO2
Genatlas (Paris)ELMO2
WikiGenes63916
SOURCE (Princeton)ELMO2
Genetics Home Reference (NIH)ELMO2
Genomic and cartography
GoldenPath hg19 (UCSC)ELMO2  -     chr20:44994690-45035271 -  20q13.12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ELMO2  -     20q13.12   [Description]    (hg38-Dec_2013)
EnsemblELMO2 - 20q13.12 [CytoView hg19]  ELMO2 - 20q13.12 [CytoView hg38]
Mapping of homologs : NCBIELMO2 [Mapview hg19]  ELMO2 [Mapview hg38]
OMIM606421   
Gene and transcription
Genbank (Entrez)AB058737 AF398886 AF417861 AK021718 AK022731
RefSeq transcript (Entrez)NM_022086 NM_133171 NM_182764
RefSeq genomic (Entrez)NC_000020 NC_018931 NT_011362 NW_004929418
Consensus coding sequences : CCDS (NCBI)ELMO2
Cluster EST : UnigeneHs.210469 [ NCBI ]
CGAP (NCI)Hs.210469
Alternative Splicing GalleryENSG00000062598
Gene ExpressionELMO2 [ NCBI-GEO ]   ELMO2 [ EBI - ARRAY_EXPRESS ]   ELMO2 [ SEEK ]   ELMO2 [ MEM ]
Gene Expression Viewer (FireBrowse)ELMO2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)63916
GTEX Portal (Tissue expression)ELMO2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96JJ3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96JJ3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96JJ3
Splice isoforms : SwissVarQ96JJ3
PhosPhoSitePlusQ96JJ3
Domaine pattern : Prosite (Expaxy)ELMO (PS51335)   
Domains : Interpro (EBI)ARM-like    ARM-type_fold    DUF3361    ELMO2    Engulfment_cell_motility_ELMO    PH_domain    PH_like_dom   
Domain families : Pfam (Sanger)DUF3361 (PF11841)    ELMO_CED12 (PF04727)   
Domain families : Pfam (NCBI)pfam11841    pfam04727   
Domain families : Smart (EMBL)PH (SM00233)  
Conserved Domain (NCBI)ELMO2
DMDM Disease mutations63916
Blocks (Seattle)ELMO2
SuperfamilyQ96JJ3
Human Protein AtlasENSG00000062598
Peptide AtlasQ96JJ3
HPRD12103
IPIIPI00940537   IPI00260090   IPI01009921   IPI00101924   IPI00642462   IPI00640649   IPI00640870   IPI00984724   IPI00643255   
Protein Interaction databases
DIP (DOE-UCLA)Q96JJ3
IntAct (EBI)Q96JJ3
FunCoupENSG00000062598
BioGRIDELMO2
STRING (EMBL)ELMO2
ZODIACELMO2
Ontologies - Pathways
QuickGOQ96JJ3
Ontology : AmiGOprotein binding  cytoplasm  cytosol  cytosol  apoptotic process  cytoskeleton organization  membrane  SH3 domain binding  receptor tyrosine kinase binding  Fc-gamma receptor signaling pathway involved in phagocytosis  innate immune response  vascular endothelial growth factor receptor signaling pathway  cell chemotaxis  cell-cell adhesion  
Ontology : EGO-EBIprotein binding  cytoplasm  cytosol  cytosol  apoptotic process  cytoskeleton organization  membrane  SH3 domain binding  receptor tyrosine kinase binding  Fc-gamma receptor signaling pathway involved in phagocytosis  innate immune response  vascular endothelial growth factor receptor signaling pathway  cell chemotaxis  cell-cell adhesion  
NDEx NetworkELMO2
Atlas of Cancer Signalling NetworkELMO2
Wikipedia pathwaysELMO2
Orthology - Evolution
OrthoDB63916
GeneTree (enSembl)ENSG00000062598
Phylogenetic Trees/Animal Genes : TreeFamELMO2
HOVERGENQ96JJ3
HOGENOMQ96JJ3
Homologs : HomoloGeneELMO2
Homology/Alignments : Family Browser (UCSC)ELMO2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerELMO2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ELMO2
dbVarELMO2
ClinVarELMO2
1000_GenomesELMO2 
Exome Variant ServerELMO2
ExAC (Exome Aggregation Consortium)ELMO2 (select the gene name)
Genetic variants : HAPMAP63916
Genomic Variants (DGV)ELMO2 [DGVbeta]
DECIPHER (Syndromes)20:44994690-45035271  ENSG00000062598
CONAN: Copy Number AnalysisELMO2 
Mutations
ICGC Data PortalELMO2 
TCGA Data PortalELMO2 
Broad Tumor PortalELMO2
OASIS PortalELMO2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICELMO2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDELMO2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ELMO2
DgiDB (Drug Gene Interaction Database)ELMO2
DoCM (Curated mutations)ELMO2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ELMO2 (select a term)
intoGenELMO2
Cancer3DELMO2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606421   
Orphanet
MedgenELMO2
Genetic Testing Registry ELMO2
NextProtQ96JJ3 [Medical]
TSGene63916
GENETestsELMO2
Huge Navigator ELMO2 [HugePedia]
snp3D : Map Gene to Disease63916
BioCentury BCIQELMO2
ClinGenELMO2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD63916
Chemical/Pharm GKB GenePA27755
Clinical trialELMO2
Miscellaneous
canSAR (ICR)ELMO2 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineELMO2
EVEXELMO2
GoPubMedELMO2
iHOPELMO2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:02:45 CET 2017

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