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ELOB (elongin B)

Identity

Alias (NCBI)SIII
TCEB2
HGNC (Hugo) ELOB
HGNC Alias symbSIII
HGNC Previous nameTCEB2
HGNC Previous nametranscription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
 transcription elongation factor B subunit 2
LocusID (NCBI) 6923
Atlas_Id 56640
Location 16p13.3  [Link to chromosome band 16p13]
Location_base_pair Starts at 2771414 and ends at 2777280 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ELOB   11619
Cards
Entrez_Gene (NCBI)ELOB    elongin B
AliasesSIII; TCEB2
GeneCards (Weizmann)ELOB
Ensembl hg19 (Hinxton)ENSG00000103363 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000103363 [Gene_View]  ENSG00000103363 [Sequence]  chr16:2771414-2777280 [Contig_View]  ELOB [Vega]
ICGC DataPortalENSG00000103363
TCGA cBioPortalELOB
AceView (NCBI)ELOB
Genatlas (Paris)ELOB
SOURCE (Princeton)ELOB
Genetics Home Reference (NIH)ELOB
Genomic and cartography
GoldenPath hg38 (UCSC)ELOB  -     chr16:2771414-2777280 -  16p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ELOB  -     16p13.3   [Description]    (hg19-Feb_2009)
GoldenPathELOB - 16p13.3 [CytoView hg19]  ELOB - 16p13.3 [CytoView hg38]
ImmunoBaseENSG00000103363
Genome Data Viewer NCBIELOB [Mapview hg19]  
OMIM600787   
Gene and transcription
Genbank (Entrez)AI191983 BC013306 BC065000 BF967495 BG329435
RefSeq transcript (Entrez)NM_007108 NM_207013
Consensus coding sequences : CCDS (NCBI)ELOB
Gene ExpressionELOB [ NCBI-GEO ]   ELOB [ EBI - ARRAY_EXPRESS ]   ELOB [ SEEK ]   ELOB [ MEM ]
Gene Expression Viewer (FireBrowse)ELOB [ Firebrowse - Broad ]
GenevisibleExpression of ELOB in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6923
GTEX Portal (Tissue expression)ELOB
Human Protein AtlasENSG00000103363-ELOB [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15370   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15370  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15370
PhosPhoSitePlusQ15370
Domaine pattern : Prosite (Expaxy)UBIQUITIN_2 (PS50053)   
Domains : Interpro (EBI)ELOB    Ubiquitin-like_dom    Ubiquitin-like_domsf   
Domain families : Pfam (Sanger)ubiquitin (PF00240)   
Domain families : Pfam (NCBI)pfam00240   
Domain families : Smart (EMBL)UBQ (SM00213)  
Conserved Domain (NCBI)ELOB
PDB (RSDB)1LM8    1LQB    1VCB    2C9W    2IZV    2JZ3    2MA9    3DCG    3ZKJ    3ZNG    3ZRC    3ZRF    3ZTC    3ZTD    3ZUN    4AJY    4AWJ    4B95    4B9K    4BKS    4BKT    4N9F    4W9C    4W9D    4W9E    4W9F    4W9G    4W9H    4W9I    4W9J    4W9K    4W9L    4WQO    5BO4    5LLI    5N4W    5NVV    5NVW    5NVX    5NVY    5NVZ    5NW0    5NW1    5NW2    5T35    6BVB    6C5X    6FMI    6FMJ    6FMK    6GFX    6GFY    6GFZ    6GMN    6GMQ    6GMR    6GMX    6HAX    6HAY    6HR2    6I4X    6I5J    6I5N    6I7Q    6I7R    6P59    6R6H    6R7F    6R7H    6R7I    6R7N    6SIS    6V9H    6ZHC   
PDB Europe1LM8    1LQB    1VCB    2C9W    2IZV    2JZ3    2MA9    3DCG    3ZKJ    3ZNG    3ZRC    3ZRF    3ZTC    3ZTD    3ZUN    4AJY    4AWJ    4B95    4B9K    4BKS    4BKT    4N9F    4W9C    4W9D    4W9E    4W9F    4W9G    4W9H    4W9I    4W9J    4W9K    4W9L    4WQO    5BO4    5LLI    5N4W    5NVV    5NVW    5NVX    5NVY    5NVZ    5NW0    5NW1    5NW2    5T35    6BVB    6C5X    6FMI    6FMJ    6FMK    6GFX    6GFY    6GFZ    6GMN    6GMQ    6GMR    6GMX    6HAX    6HAY    6HR2    6I4X    6I5J    6I5N    6I7Q    6I7R    6P59    6R6H    6R7F    6R7H    6R7I    6R7N    6SIS    6V9H    6ZHC   
PDB (PDBSum)1LM8    1LQB    1VCB    2C9W    2IZV    2JZ3    2MA9    3DCG    3ZKJ    3ZNG    3ZRC    3ZRF    3ZTC    3ZTD    3ZUN    4AJY    4AWJ    4B95    4B9K    4BKS    4BKT    4N9F    4W9C    4W9D    4W9E    4W9F    4W9G    4W9H    4W9I    4W9J    4W9K    4W9L    4WQO    5BO4    5LLI    5N4W    5NVV    5NVW    5NVX    5NVY    5NVZ    5NW0    5NW1    5NW2    5T35    6BVB    6C5X    6FMI    6FMJ    6FMK    6GFX    6GFY    6GFZ    6GMN    6GMQ    6GMR    6GMX    6HAX    6HAY    6HR2    6I4X    6I5J    6I5N    6I7Q    6I7R    6P59    6R6H    6R7F    6R7H    6R7I    6R7N    6SIS    6V9H    6ZHC   
PDB (IMB)1LM8    1LQB    1VCB    2C9W    2IZV    2JZ3    2MA9    3DCG    3ZKJ    3ZNG    3ZRC    3ZRF    3ZTC    3ZTD    3ZUN    4AJY    4AWJ    4B95    4B9K    4BKS    4BKT    4N9F    4W9C    4W9D    4W9E    4W9F    4W9G    4W9H    4W9I    4W9J    4W9K    4W9L    4WQO    5BO4    5LLI    5N4W    5NVV    5NVW    5NVX    5NVY    5NVZ    5NW0    5NW1    5NW2    5T35    6BVB    6C5X    6FMI    6FMJ    6FMK    6GFX    6GFY    6GFZ    6GMN    6GMQ    6GMR    6GMX    6HAX    6HAY    6HR2    6I4X    6I5J    6I5N    6I7Q    6I7R    6P59    6R6H    6R7F    6R7H    6R7I    6R7N    6SIS    6V9H    6ZHC   
Structural Biology KnowledgeBase1LM8    1LQB    1VCB    2C9W    2IZV    2JZ3    2MA9    3DCG    3ZKJ    3ZNG    3ZRC    3ZRF    3ZTC    3ZTD    3ZUN    4AJY    4AWJ    4B95    4B9K    4BKS    4BKT    4N9F    4W9C    4W9D    4W9E    4W9F    4W9G    4W9H    4W9I    4W9J    4W9K    4W9L    4WQO    5BO4    5LLI    5N4W    5NVV    5NVW    5NVX    5NVY    5NVZ    5NW0    5NW1    5NW2    5T35    6BVB    6C5X    6FMI    6FMJ    6FMK    6GFX    6GFY    6GFZ    6GMN    6GMQ    6GMR    6GMX    6HAX    6HAY    6HR2    6I4X    6I5J    6I5N    6I7Q    6I7R    6P59    6R6H    6R7F    6R7H    6R7I    6R7N    6SIS    6V9H    6ZHC   
SCOP (Structural Classification of Proteins)1LM8    1LQB    1VCB    2C9W    2IZV    2JZ3    2MA9    3DCG    3ZKJ    3ZNG    3ZRC    3ZRF    3ZTC    3ZTD    3ZUN    4AJY    4AWJ    4B95    4B9K    4BKS    4BKT    4N9F    4W9C    4W9D    4W9E    4W9F    4W9G    4W9H    4W9I    4W9J    4W9K    4W9L    4WQO    5BO4    5LLI    5N4W    5NVV    5NVW    5NVX    5NVY    5NVZ    5NW0    5NW1    5NW2    5T35    6BVB    6C5X    6FMI    6FMJ    6FMK    6GFX    6GFY    6GFZ    6GMN    6GMQ    6GMR    6GMX    6HAX    6HAY    6HR2    6I4X    6I5J    6I5N    6I7Q    6I7R    6P59    6R6H    6R7F    6R7H    6R7I    6R7N    6SIS    6V9H    6ZHC   
CATH (Classification of proteins structures)1LM8    1LQB    1VCB    2C9W    2IZV    2JZ3    2MA9    3DCG    3ZKJ    3ZNG    3ZRC    3ZRF    3ZTC    3ZTD    3ZUN    4AJY    4AWJ    4B95    4B9K    4BKS    4BKT    4N9F    4W9C    4W9D    4W9E    4W9F    4W9G    4W9H    4W9I    4W9J    4W9K    4W9L    4WQO    5BO4    5LLI    5N4W    5NVV    5NVW    5NVX    5NVY    5NVZ    5NW0    5NW1    5NW2    5T35    6BVB    6C5X    6FMI    6FMJ    6FMK    6GFX    6GFY    6GFZ    6GMN    6GMQ    6GMR    6GMX    6HAX    6HAY    6HR2    6I4X    6I5J    6I5N    6I7Q    6I7R    6P59    6R6H    6R7F    6R7H    6R7I    6R7N    6SIS    6V9H    6ZHC   
SuperfamilyQ15370
AlphaFold pdb e-kbQ15370   
Human Protein Atlas [tissue]ENSG00000103363-ELOB [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q15370
IntAct (EBI)Q15370
BioGRIDELOB
STRING (EMBL)ELOB
ZODIACELOB
Ontologies - Pathways
QuickGOQ15370
Ontology : AmiGOprotein binding  nucleoplasm  cytosol  transcription by RNA polymerase II  transcription elongation from RNA polymerase II promoter  protein ubiquitination  protein ubiquitination  VCB complex  Cul2-RING ubiquitin ligase complex  Cul5-RING ubiquitin ligase complex  ubiquitin protein ligase binding  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  post-translational protein modification  regulation of transcription from RNA polymerase II promoter in response to hypoxia  protein-containing complex assembly  elongin complex  
Ontology : EGO-EBIprotein binding  nucleoplasm  cytosol  transcription by RNA polymerase II  transcription elongation from RNA polymerase II promoter  protein ubiquitination  protein ubiquitination  VCB complex  Cul2-RING ubiquitin ligase complex  Cul5-RING ubiquitin ligase complex  ubiquitin protein ligase binding  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  post-translational protein modification  regulation of transcription from RNA polymerase II promoter in response to hypoxia  protein-containing complex assembly  elongin complex  
NDEx NetworkELOB
Atlas of Cancer Signalling NetworkELOB
Wikipedia pathwaysELOB
Orthology - Evolution
OrthoDB6923
GeneTree (enSembl)ENSG00000103363
Phylogenetic Trees/Animal Genes : TreeFamELOB
Homologs : HomoloGeneELOB
Homology/Alignments : Family Browser (UCSC)ELOB
Gene fusions - Rearrangements
Fusion : QuiverELOB
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerELOB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ELOB
dbVarELOB
ClinVarELOB
MonarchELOB
1000_GenomesELOB 
Exome Variant ServerELOB
GNOMAD BrowserENSG00000103363
Varsome BrowserELOB
ACMGELOB variants
VarityQ15370
Genomic Variants (DGV)ELOB [DGVbeta]
DECIPHERELOB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisELOB 
Mutations
ICGC Data PortalELOB 
TCGA Data PortalELOB 
Broad Tumor PortalELOB
OASIS PortalELOB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICELOB  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DELOB
Mutations and Diseases : HGMDELOB
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaELOB
DgiDB (Drug Gene Interaction Database)ELOB
DoCM (Curated mutations)ELOB
CIViC (Clinical Interpretations of Variants in Cancer)ELOB
Cancer3DELOB
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600787   
Orphanet
DisGeNETELOB
MedgenELOB
Genetic Testing Registry ELOB
NextProtQ15370 [Medical]
GENETestsELOB
Target ValidationELOB
Huge Navigator ELOB [HugePedia]
ClinGenELOB
Clinical trials, drugs, therapy
MyCancerGenomeELOB
Protein Interactions : CTDELOB
Pharm GKB GenePA36378
PharosQ15370
Clinical trialELOB
Miscellaneous
canSAR (ICR)ELOB
HarmonizomeELOB
DataMed IndexELOB
Probes
Litterature
PubMed241 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXELOB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:08:03 CEST 2021

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