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ELP2 (elongator acetyltransferase complex subunit 2)

Identity

Alias_namesSTATIP1
signal transducer and activator of transcription 3 interacting protein 1
elongation protein 2 homolog (S. cerevisiae)
Alias_symbol (synonym)FLJ10879
StIP
Other aliasMRT58
SHINC-2
HGNC (Hugo) ELP2
LocusID (NCBI) 55250
Atlas_Id 62806
Location 18q12.2  [Link to chromosome band 18q12]
Location_base_pair Starts at 36129874 and ends at 36177922 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ALPK1 (4q25) / ELP2 (18q12.2)ANKRD40 (17q21.33) / ELP2 (18q12.2)ELP2 (18q12.2) / GALNT1 (18q12.2)
ELP2 (18q12.2) / MAP1A (15q15.3)ELP2 (18q12.2) / MAPRE2 (18q12.1)ELP2 MAPRE2
ELP2 GALNT1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ELP2   18248
Cards
Entrez_Gene (NCBI)ELP2  55250  elongator acetyltransferase complex subunit 2
AliasesMRT58; SHINC-2; STATIP1; StIP
GeneCards (Weizmann)ELP2
Ensembl hg19 (Hinxton)ENSG00000134759 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134759 [Gene_View]  chr18:36129874-36177922 [Contig_View]  ELP2 [Vega]
ICGC DataPortalENSG00000134759
TCGA cBioPortalELP2
AceView (NCBI)ELP2
Genatlas (Paris)ELP2
WikiGenes55250
SOURCE (Princeton)ELP2
Genetics Home Reference (NIH)ELP2
Genomic and cartography
GoldenPath hg38 (UCSC)ELP2  -     chr18:36129874-36177922 +  18q12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ELP2  -     18q12.2   [Description]    (hg19-Feb_2009)
EnsemblELP2 - 18q12.2 [CytoView hg19]  ELP2 - 18q12.2 [CytoView hg38]
Mapping of homologs : NCBIELP2 [Mapview hg19]  ELP2 [Mapview hg38]
OMIM616054   617270   
Gene and transcription
Genbank (Entrez)AF332505 AF403223 AK001741 AK022709 AK095780
RefSeq transcript (Entrez)NM_001242875 NM_001242876 NM_001242877 NM_001242878 NM_001242879 NM_001324465 NM_001324466 NM_001324467 NM_001324468 NM_001324469 NM_018255
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ELP2
Cluster EST : UnigeneHs.606040 [ NCBI ]
CGAP (NCI)Hs.606040
Alternative Splicing GalleryENSG00000134759
Gene ExpressionELP2 [ NCBI-GEO ]   ELP2 [ EBI - ARRAY_EXPRESS ]   ELP2 [ SEEK ]   ELP2 [ MEM ]
Gene Expression Viewer (FireBrowse)ELP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55250
GTEX Portal (Tissue expression)ELP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6IA86   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6IA86  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6IA86
Splice isoforms : SwissVarQ6IA86
PhosPhoSitePlusQ6IA86
Domaine pattern : Prosite (Expaxy)WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_dom   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)ELP2
DMDM Disease mutations55250
Blocks (Seattle)ELP2
SuperfamilyQ6IA86
Human Protein AtlasENSG00000134759
Peptide AtlasQ6IA86
HPRD15443
IPIIPI00015560   IPI00289763   IPI00304246   IPI00470701   IPI01011734   IPI01010416   IPI01012761   IPI00296893   IPI00643466   IPI00909025   IPI01013745   IPI01014093   
Protein Interaction databases
DIP (DOE-UCLA)Q6IA86
IntAct (EBI)Q6IA86
FunCoupENSG00000134759
BioGRIDELP2
STRING (EMBL)ELP2
ZODIACELP2
Ontologies - Pathways
QuickGOQ6IA86
Ontology : AmiGOhistone acetyltransferase complex  RNA polymerase II core binding  cytoplasm  cytosol  regulation of transcription from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  transcription elongation factor complex  protein kinase binding  Elongator holoenzyme complex  regulation of JAK-STAT cascade  
Ontology : EGO-EBIhistone acetyltransferase complex  RNA polymerase II core binding  cytoplasm  cytosol  regulation of transcription from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  transcription elongation factor complex  protein kinase binding  Elongator holoenzyme complex  regulation of JAK-STAT cascade  
NDEx NetworkELP2
Atlas of Cancer Signalling NetworkELP2
Wikipedia pathwaysELP2
Orthology - Evolution
OrthoDB55250
GeneTree (enSembl)ENSG00000134759
Phylogenetic Trees/Animal Genes : TreeFamELP2
HOVERGENQ6IA86
HOGENOMQ6IA86
Homologs : HomoloGeneELP2
Homology/Alignments : Family Browser (UCSC)ELP2
Gene fusions - Rearrangements
Fusion: TCGAELP2 MAPRE2
Fusion: TCGAELP2 GALNT1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerELP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ELP2
dbVarELP2
ClinVarELP2
1000_GenomesELP2 
Exome Variant ServerELP2
ExAC (Exome Aggregation Consortium)ELP2 (select the gene name)
Genetic variants : HAPMAP55250
Genomic Variants (DGV)ELP2 [DGVbeta]
DECIPHERELP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisELP2 
Mutations
ICGC Data PortalELP2 
TCGA Data PortalELP2 
Broad Tumor PortalELP2
OASIS PortalELP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICELP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDELP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ELP2
DgiDB (Drug Gene Interaction Database)ELP2
DoCM (Curated mutations)ELP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ELP2 (select a term)
intoGenELP2
Cancer3DELP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616054    617270   
Orphanet
MedgenELP2
Genetic Testing Registry ELP2
NextProtQ6IA86 [Medical]
TSGene55250
GENETestsELP2
Target ValidationELP2
Huge Navigator ELP2 [HugePedia]
snp3D : Map Gene to Disease55250
BioCentury BCIQELP2
ClinGenELP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55250
Chemical/Pharm GKB GenePA162385051
Clinical trialELP2
Miscellaneous
canSAR (ICR)ELP2 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineELP2
EVEXELP2
GoPubMedELP2
iHOPELP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:07:03 CEST 2017

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