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EMC6 (ER membrane protein complex subunit 6)

Identity

Alias (NCBI)RAB5IFL
TMEM93
HGNC (Hugo) EMC6
HGNC Alias symbMGC2963
RAB5IFL
HGNC Previous nameTMEM93
HGNC Previous nametransmembrane protein 93
LocusID (NCBI) 83460
Atlas_Id 57402
Location 17p13.2  [Link to chromosome band 17p13]
Location_base_pair Starts at 3668812 and ends at 3669665 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EMC6 (17p13.2) / CEACAM19 (19q13.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)EMC6   28430
Cards
Entrez_Gene (NCBI)EMC6    ER membrane protein complex subunit 6
AliasesRAB5IFL; TMEM93
GeneCards (Weizmann)EMC6
Ensembl hg19 (Hinxton)ENSG00000127774 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000127774 [Gene_View]  ENSG00000127774 [Sequence]  chr17:3668812-3669665 [Contig_View]  EMC6 [Vega]
ICGC DataPortalENSG00000127774
TCGA cBioPortalEMC6
AceView (NCBI)EMC6
Genatlas (Paris)EMC6
SOURCE (Princeton)EMC6
Genetics Home Reference (NIH)EMC6
Genomic and cartography
GoldenPath hg38 (UCSC)EMC6  -     chr17:3668812-3669665 +  17p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EMC6  -     17p13.2   [Description]    (hg19-Feb_2009)
GoldenPathEMC6 - 17p13.2 [CytoView hg19]  EMC6 - 17p13.2 [CytoView hg38]
ImmunoBaseENSG00000127774
Genome Data Viewer NCBIEMC6 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AA161105 BC001409 BM825446 BQ277705 BU931404
RefSeq transcript (Entrez)NM_001014764 NM_031298
Consensus coding sequences : CCDS (NCBI)EMC6
Gene ExpressionEMC6 [ NCBI-GEO ]   EMC6 [ EBI - ARRAY_EXPRESS ]   EMC6 [ SEEK ]   EMC6 [ MEM ]
Gene Expression Viewer (FireBrowse)EMC6 [ Firebrowse - Broad ]
GenevisibleExpression of EMC6 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)83460
GTEX Portal (Tissue expression)EMC6
Human Protein AtlasENSG00000127774-EMC6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BV81   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BV81  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BV81
PhosPhoSitePlusQ9BV81
Domains : Interpro (EBI)Emc6    Rab5IP_fam   
Domain families : Pfam (Sanger)Rab5ip (PF07019)   
Domain families : Pfam (NCBI)pfam07019   
Conserved Domain (NCBI)EMC6
PDB (RSDB)6WW7    6Z3W   
PDB Europe6WW7    6Z3W   
PDB (PDBSum)6WW7    6Z3W   
PDB (IMB)6WW7    6Z3W   
Structural Biology KnowledgeBase6WW7    6Z3W   
SCOP (Structural Classification of Proteins)6WW7    6Z3W   
CATH (Classification of proteins structures)6WW7    6Z3W   
SuperfamilyQ9BV81
AlphaFold pdb e-kbQ9BV81   
Human Protein Atlas [tissue]ENSG00000127774-EMC6 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q9BV81
IntAct (EBI)Q9BV81
BioGRIDEMC6
STRING (EMBL)EMC6
ZODIACEMC6
Ontologies - Pathways
QuickGOQ9BV81
Ontology : AmiGOautophagosome assembly  autophagosome assembly  protein binding  integral component of membrane  integral component of endoplasmic reticulum membrane  membrane insertase activity  protein insertion into ER membrane by stop-transfer membrane-anchor sequence  tail-anchored membrane protein insertion into ER membrane  EMC complex  EMC complex  integral component of omegasome membrane  
Ontology : EGO-EBIautophagosome assembly  autophagosome assembly  protein binding  integral component of membrane  integral component of endoplasmic reticulum membrane  membrane insertase activity  protein insertion into ER membrane by stop-transfer membrane-anchor sequence  tail-anchored membrane protein insertion into ER membrane  EMC complex  EMC complex  integral component of omegasome membrane  
NDEx NetworkEMC6
Atlas of Cancer Signalling NetworkEMC6
Wikipedia pathwaysEMC6
Orthology - Evolution
OrthoDB83460
GeneTree (enSembl)ENSG00000127774
Phylogenetic Trees/Animal Genes : TreeFamEMC6
Homologs : HomoloGeneEMC6
Homology/Alignments : Family Browser (UCSC)EMC6
Gene fusions - Rearrangements
Fusion : QuiverEMC6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEMC6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EMC6
dbVarEMC6
ClinVarEMC6
MonarchEMC6
1000_GenomesEMC6 
Exome Variant ServerEMC6
GNOMAD BrowserENSG00000127774
Varsome BrowserEMC6
ACMGEMC6 variants
VarityQ9BV81
Genomic Variants (DGV)EMC6 [DGVbeta]
DECIPHEREMC6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEMC6 
Mutations
ICGC Data PortalEMC6 
TCGA Data PortalEMC6 
Broad Tumor PortalEMC6
OASIS PortalEMC6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEMC6  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DEMC6
Mutations and Diseases : HGMDEMC6
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaEMC6
DgiDB (Drug Gene Interaction Database)EMC6
DoCM (Curated mutations)EMC6
CIViC (Clinical Interpretations of Variants in Cancer)EMC6
Cancer3DEMC6
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETEMC6
MedgenEMC6
Genetic Testing Registry EMC6
NextProtQ9BV81 [Medical]
GENETestsEMC6
Target ValidationEMC6
Huge Navigator EMC6 [HugePedia]
ClinGenEMC6
Clinical trials, drugs, therapy
MyCancerGenomeEMC6
Protein Interactions : CTDEMC6
Pharm GKB GenePA142670745
PharosQ9BV81
Clinical trialEMC6
Miscellaneous
canSAR (ICR)EMC6
HarmonizomeEMC6
DataMed IndexEMC6
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXEMC6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:08:07 CEST 2021

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