EMP1 (epithelial membrane protein 1)

2003-06-01  

Identity

HGNC
LOCATION
12p13.1
LOCUSID
ALIAS
CL-20,EMP-1,TMP
FUSION GENES

Other Information

Locus ID:

NCBI: 2012
MIM: 602333
HGNC: 3333
Ensembl: ENSG00000134531

Variants:

dbSNP: 2012
ClinVar: 2012
TCGA: ENSG00000134531
COSMIC: EMP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134531ENST00000256951P54849
ENSG00000134531ENST00000256951A0A024RAT0
ENSG00000134531ENST00000396301P54849
ENSG00000134531ENST00000431267J3KQX4
ENSG00000134531ENST00000537612F5H397
ENSG00000134531ENST00000538364F5GYV0
ENSG00000134531ENST00000544053F5H2P5

Expression (GTEx)

0
500
1000
1500

References

Pubmed IDYearTitleCitations
246255312014EMP1, a novel poor prognostic factor in pediatric leukemia regulates prednisolone resistance, cell proliferation, migration and adhesion.19
160878802005Epithelial membrane protein-1 is a biomarker of gefitinib resistance.17
126324832003Analysis of gene expression profile induced by EMP-1 in esophageal cancer cells using cDNA Microarray.14
209805312011The expression of EMP1 is downregulated in oral squamous cell carcinoma and possibly associated with tumour metastasis.14
208006032010Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.12
242929522014EMP1 inhibits nasopharyngeal cancer cell growth and metastasis through induction apoptosis and angiogenesis.10
243387112014EMP1 regulates caspase-9 and VEGFC expression and suppresses prostate cancer cell proliferation and invasion.10
249201672014Association of EMP1 with gastric carcinoma invasion, survival and prognosis.10
253946712015SOS1 and Ras regulate epithelial tight junction formation in the human airway through EMP1.10
232712822012EMP-1 promotes tumorigenesis of NSCLC through PI3K/AKT pathway.9

Citation

Dessen P

EMP1 (epithelial membrane protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40448/emp1