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EMP2 (epithelial membrane protein 2)

Identity

Alias_symbol (synonym)XMP
Other alias
HGNC (Hugo) EMP2
LocusID (NCBI) 2013
Atlas_Id 50637
Location 16p13.13  [Link to chromosome band 16p13]
Location_base_pair Starts at 10622279 and ends at 10674573 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
EMP2 (16p13.13) / EMP2 (16p13.13)KRT81 (12q13.13) / EMP2 (16p13.13)SUPT16H (14q11.2) / EMP2 (16p13.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EMP2   3334
Cards
Entrez_Gene (NCBI)EMP2  2013  epithelial membrane protein 2
AliasesXMP
GeneCards (Weizmann)EMP2
Ensembl hg19 (Hinxton)ENSG00000213853 [Gene_View]  chr16:10622279-10674573 [Contig_View]  EMP2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000213853 [Gene_View]  chr16:10622279-10674573 [Contig_View]  EMP2 [Vega]
ICGC DataPortalENSG00000213853
TCGA cBioPortalEMP2
AceView (NCBI)EMP2
Genatlas (Paris)EMP2
WikiGenes2013
SOURCE (Princeton)EMP2
Genetics Home Reference (NIH)EMP2
Genomic and cartography
GoldenPath hg19 (UCSC)EMP2  -     chr16:10622279-10674573 -  16p13.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)EMP2  -     16p13.13   [Description]    (hg38-Dec_2013)
EnsemblEMP2 - 16p13.13 [CytoView hg19]  EMP2 - 16p13.13 [CytoView hg38]
Mapping of homologs : NCBIEMP2 [Mapview hg19]  EMP2 [Mapview hg38]
OMIM602334   615861   
Gene and transcription
Genbank (Entrez)AA854747 AF190163 AK096403 AK123602 AK127600
RefSeq transcript (Entrez)NM_001424
RefSeq genomic (Entrez)NC_000016 NC_018927 NG_042058 NT_010393 NW_004929400
Consensus coding sequences : CCDS (NCBI)EMP2
Cluster EST : UnigeneHs.531561 [ NCBI ]
CGAP (NCI)Hs.531561
Alternative Splicing GalleryENSG00000213853
Gene ExpressionEMP2 [ NCBI-GEO ]   EMP2 [ EBI - ARRAY_EXPRESS ]   EMP2 [ SEEK ]   EMP2 [ MEM ]
Gene Expression Viewer (FireBrowse)EMP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2013
GTEX Portal (Tissue expression)EMP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP54851   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP54851  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP54851
Splice isoforms : SwissVarP54851
PhosPhoSitePlusP54851
Domaine pattern : Prosite (Expaxy)PMP22_1 (PS01221)    PMP22_2 (PS01222)   
Domains : Interpro (EBI)EMP-2    PMP22/EMP/MP20/Claudin    PMP22_EMP_MP20   
Domain families : Pfam (Sanger)PMP22_Claudin (PF00822)   
Domain families : Pfam (NCBI)pfam00822   
Conserved Domain (NCBI)EMP2
DMDM Disease mutations2013
Blocks (Seattle)EMP2
SuperfamilyP54851
Human Protein AtlasENSG00000213853
Peptide AtlasP54851
HPRD11893
IPIIPI00008895   IPI00848293   
Protein Interaction databases
DIP (DOE-UCLA)P54851
IntAct (EBI)P54851
FunCoupENSG00000213853
BioGRIDEMP2
STRING (EMBL)EMP2
ZODIACEMP2
Ontologies - Pathways
QuickGOP54851
Ontology : AmiGOGolgi membrane  membrane raft assembly  T cell mediated cytotoxicity  positive regulation of cell-matrix adhesion  regulation of glomerular filtration  integrin binding  protein binding  nucleus  cytoplasm  Golgi apparatus  cytosol  cytosol  plasma membrane  caveola  actin filament organization  cell adhesion  cell-matrix adhesion  embryo implantation  cell death  cell proliferation  positive regulation of cell proliferation  cell surface  regulation of endothelial cell migration  integral component of membrane  apical plasma membrane  cell migration  kinase binding  protein kinase binding  cytoplasmic vesicle  bleb assembly  activation of protein kinase activity  protein localization to cell surface  blood vessel endothelial cell migration  regulation of kinase activity  early endosome to late endosome transport  membrane raft  apical part of cell  regulation of angiogenesis  regulation of angiogenesis  actin-mediated cell contraction  caveola assembly  protein localization to plasma membrane  positive regulation of integrin-mediated signaling pathway  regulation of vasculogenesis  
Ontology : EGO-EBIGolgi membrane  membrane raft assembly  T cell mediated cytotoxicity  positive regulation of cell-matrix adhesion  regulation of glomerular filtration  integrin binding  protein binding  nucleus  cytoplasm  Golgi apparatus  cytosol  cytosol  plasma membrane  caveola  actin filament organization  cell adhesion  cell-matrix adhesion  embryo implantation  cell death  cell proliferation  positive regulation of cell proliferation  cell surface  regulation of endothelial cell migration  integral component of membrane  apical plasma membrane  cell migration  kinase binding  protein kinase binding  cytoplasmic vesicle  bleb assembly  activation of protein kinase activity  protein localization to cell surface  blood vessel endothelial cell migration  regulation of kinase activity  early endosome to late endosome transport  membrane raft  apical part of cell  regulation of angiogenesis  regulation of angiogenesis  actin-mediated cell contraction  caveola assembly  protein localization to plasma membrane  positive regulation of integrin-mediated signaling pathway  regulation of vasculogenesis  
NDEx NetworkEMP2
Atlas of Cancer Signalling NetworkEMP2
Wikipedia pathwaysEMP2
Orthology - Evolution
OrthoDB2013
GeneTree (enSembl)ENSG00000213853
Phylogenetic Trees/Animal Genes : TreeFamEMP2
HOVERGENP54851
HOGENOMP54851
Homologs : HomoloGeneEMP2
Homology/Alignments : Family Browser (UCSC)EMP2
Gene fusions - Rearrangements
Fusion : MitelmanKRT81/EMP2 [12q13.13/16p13.13]  [t(12;16)(q13;p13)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEMP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EMP2
dbVarEMP2
ClinVarEMP2
1000_GenomesEMP2 
Exome Variant ServerEMP2
ExAC (Exome Aggregation Consortium)EMP2 (select the gene name)
Genetic variants : HAPMAP2013
Genomic Variants (DGV)EMP2 [DGVbeta]
DECIPHER (Syndromes)16:10622279-10674573  ENSG00000213853
CONAN: Copy Number AnalysisEMP2 
Mutations
ICGC Data PortalEMP2 
TCGA Data PortalEMP2 
Broad Tumor PortalEMP2
OASIS PortalEMP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEMP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEMP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EMP2
DgiDB (Drug Gene Interaction Database)EMP2
DoCM (Curated mutations)EMP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EMP2 (select a term)
intoGenEMP2
Cancer3DEMP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602334    615861   
Orphanet12193    12188    12189    12187   
MedgenEMP2
Genetic Testing Registry EMP2
NextProtP54851 [Medical]
TSGene2013
GENETestsEMP2
Huge Navigator EMP2 [HugePedia]
snp3D : Map Gene to Disease2013
BioCentury BCIQEMP2
ClinGenEMP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2013
Chemical/Pharm GKB GenePA27771
Clinical trialEMP2
Miscellaneous
canSAR (ICR)EMP2 (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEMP2
EVEXEMP2
GoPubMedEMP2
iHOPEMP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:00:05 CEST 2017

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