| Nomenclature |
|---|
| HGNC (Hugo) | EMX2 3341 |
| Cards |
|---|
| Entrez_Gene (NCBI) | EMX2 2018 empty spiracles homeobox 2 |
| Aliases | |
| GeneCards (Weizmann) | EMX2 |
| Ensembl hg19 (Hinxton) | ENSG00000170370 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000170370 [Gene_View] ENSG00000170370 [Sequence] chr10:117542746-117549546 [Contig_View] EMX2 [Vega] |
| ICGC DataPortal | ENSG00000170370 |
| TCGA cBioPortal | EMX2 |
| AceView (NCBI) | EMX2 |
| Genatlas (Paris) | EMX2 |
| WikiGenes | 2018 |
| SOURCE (Princeton) | EMX2 |
| Genetics Home Reference (NIH) | EMX2 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | EMX2 - chr10:117542746-117549546 + 10q26.11 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | EMX2 - 10q26.11 [Description] (hg19-Feb_2009) |
| GoldenPath | EMX2 - 10q26.11 [CytoView hg19] EMX2 - 10q26.11 [CytoView hg38] |
| Genome Data Viewer NCBI | EMX2 [Mapview hg19] |
| OMIM | 269160 600035 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AF301598 AI701984 AK055041 AK311352 AL161811 |
| RefSeq transcript (Entrez) | NM_001165924 NM_004098 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | EMX2 |
| Alternative Splicing Gallery | ENSG00000170370 |
| Gene Expression | EMX2 [ NCBI-GEO ] EMX2 [ EBI - ARRAY_EXPRESS ]
EMX2 [ SEEK ] EMX2 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | EMX2 [ Firebrowse - Broad ] |
| Genevisible | Expression of EMX2 in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 2018 |
| GTEX Portal (Tissue expression) | EMX2 |
| Human Protein Atlas | ENSG00000170370-EMX2 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q04743 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q04743 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q04743 |
| Splice isoforms : SwissVar | Q04743 |
| PhosPhoSitePlus | Q04743 |
| Domaine pattern : Prosite (Expaxy) | HOMEOBOX_1 (PS00027) HOMEOBOX_2 (PS50071) |
| Domains : Interpro (EBI) | Homeobox-like_sf Homeobox_CS Homeobox_dom Homeobox_metazoa HTH_motif |
| Domain families : Pfam (Sanger) | Homeodomain (PF00046) |
| Domain families : Pfam (NCBI) | pfam00046 |
| Domain families : Smart (EMBL) | HOX (SM00389) |
| Conserved Domain (NCBI) | EMX2 |
| DMDM Disease mutations | 2018 |
| Superfamily | Q04743 |
| Human Protein Atlas [tissue] | ENSG00000170370-EMX2 [tissue] |
| Peptide Atlas | Q04743 |
| HPRD | 02495 |
| IPI | IPI00029166 IPI00947443 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q04743 |
| IntAct (EBI) | Q04743 |
| FunCoup | ENSG00000170370 |
| BioGRID | EMX2 |
| STRING (EMBL) | EMX2 |
| ZODIAC | EMX2 |
| Ontologies - Pathways |
|---|
| QuickGO | Q04743 |
| Ontology : AmiGO | negative regulation of transcription by RNA polymerase II nuclear chromatin RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific protein binding nucleus regulation of transcription by RNA polymerase II central nervous system development brain development anterior/posterior pattern specification dentate gyrus development cerebral cortex regionalization cell proliferation in forebrain forebrain cell migration neuron differentiation response to drug ureter morphogenesis |
| Ontology : EGO-EBI | negative regulation of transcription by RNA polymerase II nuclear chromatin RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific protein binding nucleus regulation of transcription by RNA polymerase II central nervous system development brain development anterior/posterior pattern specification dentate gyrus development cerebral cortex regionalization cell proliferation in forebrain forebrain cell migration neuron differentiation response to drug ureter morphogenesis |
| NDEx Network | EMX2 |
| Atlas of Cancer Signalling Network | EMX2 |
| Wikipedia pathways | EMX2 |
| Orthology - Evolution |
|---|
| OrthoDB | 2018 |
| GeneTree (enSembl) | ENSG00000170370 |
| Phylogenetic Trees/Animal Genes : TreeFam | EMX2 |
| HOGENOM | Q04743 |
| Homologs : HomoloGene | EMX2 |
| Homology/Alignments : Family Browser (UCSC) | EMX2 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | EMX2 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | EMX2 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | EMX2 |
| dbVar | EMX2 |
| ClinVar | EMX2 |
| 1000_Genomes | EMX2 |
| Exome Variant Server | EMX2 |
| GNOMAD Browser | ENSG00000170370 |
| Varsome Browser | EMX2 |
| Genetic variants : HAPMAP | 2018 |
| Genomic Variants (DGV) | EMX2 [DGVbeta] |
| DECIPHER | EMX2 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | EMX2 |
| Mutations |
|---|
| ICGC Data Portal | EMX2 |
| TCGA Data Portal | EMX2 |
| Broad Tumor Portal | EMX2 |
| OASIS Portal | EMX2 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | EMX2 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | EMX2 |
| Mutations and Diseases : HGMD | EMX2 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | select EMX2 |
| DgiDB (Drug Gene Interaction Database) | EMX2 |
| DoCM (Curated mutations) | EMX2 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | EMX2 (select a term) |
| intoGen | EMX2 |
| Cancer3D | EMX2 (select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 269160 600035 |
| Orphanet | 580 |
| DisGeNET | EMX2 |
| Medgen | EMX2 |
| Genetic Testing Registry | EMX2
|
| NextProt | Q04743 [Medical] |
| TSGene | 2018 |
| GENETests | EMX2 |
| Open Targets Genetics | ENSG00000170370 [validation] |
| snp3D : Map Gene to Disease | 2018 |
| BioCentury BCIQ | EMX2 |
| ClinGen | EMX2 (curated) |
| Clinical trials, drugs, therapy |
|---|
| Protein Interactions : CTD | 2018 |
| Pharm GKB Gene | PA27778 |
| Clinical trial | EMX2 |
| Miscellaneous |
|---|
| canSAR (ICR) | EMX2 (select the gene name) |
| Harmonizome | EMX2 |
| DataMed Index | EMX2 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 44 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | EMX2 |
| EVEX | EMX2 |
