| Nomenclature |
HGNC (Hugo) | EMX2 3341 |
| Cards |
Entrez_Gene (NCBI) | EMX2 empty spiracles homeobox 2 |
Aliases | |
GeneCards (Weizmann) | EMX2 |
Ensembl hg19 (Hinxton) | ENSG00000170370 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000170370 [Gene_View]  ENSG00000170370 [Sequence] chr10:117542746-117549546 [Contig_View] EMX2 [Vega] |
ICGC DataPortal | ENSG00000170370 |
TCGA cBioPortal | EMX2 |
AceView (NCBI) | EMX2 |
Genatlas (Paris) | EMX2 |
SOURCE (Princeton) | EMX2 |
Genetics Home Reference (NIH) | EMX2 |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | EMX2 - chr10:117542746-117549546 + 10q26.11 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | EMX2 - 10q26.11 [Description] (hg19-Feb_2009) |
GoldenPath | EMX2 - 10q26.11 [CytoView hg19] EMX2 - 10q26.11 [CytoView hg38] |
ImmunoBase | ENSG00000170370 |
genome Data Viewer NCBI | EMX2 [Mapview hg19] |
OMIM | 269160 600035 |
| Gene and transcription |
Genbank (Entrez) | AF301598 AI701984 AK055041 AK311352 AL161811 |
RefSeq transcript (Entrez) | NM_001165924 NM_004098 |
RefSeq genomic (Entrez) | |
Consensus coding sequences : CCDS (NCBI) | EMX2 |
Alternative Splicing Gallery | ENSG00000170370 |
Gene Expression | EMX2 [ NCBI-GEO ] EMX2 [ EBI - ARRAY_EXPRESS ]
EMX2 [ SEEK ] EMX2 [ MEM ] |
Gene Expression Viewer (FireBrowse) | EMX2 [ Firebrowse - Broad ] |
Genevisible | Expression of EMX2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 2018 |
GTEX Portal (Tissue expression) | EMX2 |
Human Protein Atlas | ENSG00000170370-EMX2 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | Q04743 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | Q04743 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | Q04743 |
Splice isoforms : SwissVar | Q04743 |
PhosPhoSitePlus | Q04743 |
Domaine pattern : Prosite (Expaxy) | HOMEOBOX_1 (PS00027) HOMEOBOX_2 (PS50071) |
Domains : Interpro (EBI) | Homeobox-like_sf Homeobox_CS Homeobox_dom Homeobox_metazoa HTH_motif |
Domain families : Pfam (Sanger) | Homeodomain (PF00046) |
Domain families : Pfam (NCBI) | pfam00046 |
Domain families : Smart (EMBL) | HOX (SM00389) |
Conserved Domain (NCBI) | EMX2 |
Blocks (Seattle) | EMX2 |
Superfamily | Q04743 |
Human Protein Atlas [tissue] | ENSG00000170370-EMX2 [tissue] |
Peptide Atlas | Q04743 |
HPRD | 02495 |
IPI | IPI00029166 IPI00947443 |
| Protein Interaction databases |
DIP (DOE-UCLA) | Q04743 |
IntAct (EBI) | Q04743 |
BioGRID | EMX2 |
STRING (EMBL) | EMX2 |
ZODIAC | EMX2 |
| Ontologies - Pathways |
QuickGO | Q04743 |
Ontology : AmiGO | negative regulation of transcription by RNA polymerase II nuclear chromatin RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific protein binding nucleus regulation of transcription by RNA polymerase II central nervous system development brain development anterior/posterior pattern specification dentate gyrus development cerebral cortex regionalization cell proliferation in forebrain forebrain cell migration neuron differentiation response to drug ureter morphogenesis |
Ontology : EGO-EBI | negative regulation of transcription by RNA polymerase II nuclear chromatin RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific protein binding nucleus regulation of transcription by RNA polymerase II central nervous system development brain development anterior/posterior pattern specification dentate gyrus development cerebral cortex regionalization cell proliferation in forebrain forebrain cell migration neuron differentiation response to drug ureter morphogenesis |
NDEx Network | EMX2 |
Atlas of Cancer Signalling Network | EMX2 |
Wikipedia pathways | EMX2 |
| Orthology - Evolution |
OrthoDB | 2018 |
GeneTree (enSembl) | ENSG00000170370 |
Phylogenetic Trees/Animal Genes : TreeFam | EMX2 |
HOGENOM | Q04743 |
Homologs : HomoloGene | EMX2 |
Homology/Alignments : Family Browser (UCSC) | EMX2 |
| Gene fusions - Rearrangements |
Fusion : Quiver | EMX2 |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | EMX2 [hg38] |
dbVar | EMX2 |
ClinVar | EMX2 |
Monarch | EMX2 |
1000_Genomes | EMX2 |
Exome Variant Server | EMX2 |
GNOMAD Browser | ENSG00000170370 |
Varsome Browser | EMX2 |
Genomic Variants (DGV) | EMX2 [DGVbeta] |
DECIPHER | EMX2 [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | EMX2 |
| Mutations |
ICGC Data Portal | EMX2 |
TCGA Data Portal | EMX2 |
Broad Tumor Portal | EMX2 |
OASIS Portal | EMX2 [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | EMX2 [overview] [genome browser] [tissue] [distribution] |
Somatic Mutations in Cancer : COSMIC3D | EMX2 |
Mutations and Diseases : HGMD | EMX2 |
LOVD (Leiden Open Variation Database) | Whole genome datasets |
LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
BioMuta | search EMX2 |
DgiDB (Drug Gene Interaction Database) | EMX2 |
DoCM (Curated mutations) | EMX2 (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | EMX2 (select a term) |
intoGen | EMX2 |
Cancer3D | EMX2(select the gene name) |
Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
---|
OMIM | 269160 600035 |
Orphanet | 580 |
DisGeNET | EMX2 |
Medgen | EMX2 |
Genetic Testing Registry | EMX2
|
NextProt | Q04743 [Medical] |
GENETests | EMX2 |
Target Validation | EMX2 |
Huge Navigator |
EMX2 [HugePedia] |
ClinGen | EMX2 (curated) |
| Clinical trials, drugs, therapy |
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MyCancerGenome | EMX2 |
Protein Interactions : CTD | |
Pharm GKB Gene | PA27778 |
Pharos | Q04743 |
Clinical trial | EMX2 |
| Miscellaneous |
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canSAR (ICR) | EMX2 (select the gene name) |
Harmonizome | EMX2 |
DataMed Index | EMX2 |
| Probes |
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| Litterature |
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PubMed | 44 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
EVEX | EMX2 |