Atlas of Genetics and Cytogenetics in Oncology and Haematology

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EMX2 (empty spiracles homeobox 2)

Identity

Alias_namesempty spiracles homolog 2 (Drosophila)
Other alias-
HGNC (Hugo) EMX2
LocusID (NCBI) 2018
Atlas_Id 40449
Location 10q26.11  [Link to chromosome band 10q26]
Location_base_pair Starts at 117542445 and ends at 117549546 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)EMX2   3341
Cards
Entrez_Gene (NCBI)EMX2  2018  empty spiracles homeobox 2
Aliases
GeneCards (Weizmann)EMX2
Ensembl hg19 (Hinxton)ENSG00000170370 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170370 [Gene_View]  chr10:117542445-117549546 [Contig_View]  EMX2 [Vega]
ICGC DataPortalENSG00000170370
TCGA cBioPortalEMX2
AceView (NCBI)EMX2
Genatlas (Paris)EMX2
WikiGenes2018
SOURCE (Princeton)EMX2
Genetics Home Reference (NIH)EMX2
Genomic and cartography
GoldenPath hg38 (UCSC)EMX2  -     chr10:117542445-117549546 +  10q26.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EMX2  -     10q26.11   [Description]    (hg19-Feb_2009)
EnsemblEMX2 - 10q26.11 [CytoView hg19]  EMX2 - 10q26.11 [CytoView hg38]
Mapping of homologs : NCBIEMX2 [Mapview hg19]  EMX2 [Mapview hg38]
OMIM269160   600035   
Gene and transcription
Genbank (Entrez)AF301598 AI701984 AK055041 AK311352 AL161811
RefSeq transcript (Entrez)NM_001165924 NM_004098
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EMX2
Cluster EST : UnigeneHs.202095 [ NCBI ]
CGAP (NCI)Hs.202095
Alternative Splicing GalleryENSG00000170370
Gene ExpressionEMX2 [ NCBI-GEO ]   EMX2 [ EBI - ARRAY_EXPRESS ]   EMX2 [ SEEK ]   EMX2 [ MEM ]
Gene Expression Viewer (FireBrowse)EMX2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2018
GTEX Portal (Tissue expression)EMX2
Human Protein AtlasENSG00000170370-EMX2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ04743   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ04743  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ04743
Splice isoforms : SwissVarQ04743
PhosPhoSitePlusQ04743
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_CS    Homeobox_dom    Homeobox_metazoa    HTH_motif   
Domain families : Pfam (Sanger)Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)EMX2
DMDM Disease mutations2018
Blocks (Seattle)EMX2
SuperfamilyQ04743
Human Protein Atlas [tissue]ENSG00000170370-EMX2 [tissue]
Peptide AtlasQ04743
HPRD02495
IPIIPI00029166   IPI00947443   
Protein Interaction databases
DIP (DOE-UCLA)Q04743
IntAct (EBI)Q04743
FunCoupENSG00000170370
BioGRIDEMX2
STRING (EMBL)EMX2
ZODIACEMX2
Ontologies - Pathways
QuickGOQ04743
Ontology : AmiGOprotein binding  nucleus  regulation of transcription, DNA-templated  anterior/posterior pattern specification  dentate gyrus development  cerebral cortex regionalization  cell proliferation in forebrain  forebrain cell migration  neuron differentiation  response to drug  sequence-specific DNA binding  renal system development  
Ontology : EGO-EBIprotein binding  nucleus  regulation of transcription, DNA-templated  anterior/posterior pattern specification  dentate gyrus development  cerebral cortex regionalization  cell proliferation in forebrain  forebrain cell migration  neuron differentiation  response to drug  sequence-specific DNA binding  renal system development  
NDEx NetworkEMX2
Atlas of Cancer Signalling NetworkEMX2
Wikipedia pathwaysEMX2
Orthology - Evolution
OrthoDB2018
GeneTree (enSembl)ENSG00000170370
Phylogenetic Trees/Animal Genes : TreeFamEMX2
HOVERGENQ04743
HOGENOMQ04743
Homologs : HomoloGeneEMX2
Homology/Alignments : Family Browser (UCSC)EMX2
Gene fusions - Rearrangements
Fusion : QuiverEMX2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEMX2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EMX2
dbVarEMX2
ClinVarEMX2
1000_GenomesEMX2 
Exome Variant ServerEMX2
ExAC (Exome Aggregation Consortium)ENSG00000170370
GNOMAD BrowserENSG00000170370
Genetic variants : HAPMAP2018
Genomic Variants (DGV)EMX2 [DGVbeta]
DECIPHEREMX2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEMX2 
Mutations
ICGC Data PortalEMX2 
TCGA Data PortalEMX2 
Broad Tumor PortalEMX2
OASIS PortalEMX2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEMX2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEMX2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EMX2
DgiDB (Drug Gene Interaction Database)EMX2
DoCM (Curated mutations)EMX2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EMX2 (select a term)
intoGenEMX2
Cancer3DEMX2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM269160    600035   
Orphanet580   
DisGeNETEMX2
MedgenEMX2
Genetic Testing Registry EMX2
NextProtQ04743 [Medical]
TSGene2018
GENETestsEMX2
Target ValidationEMX2
Huge Navigator EMX2 [HugePedia]
snp3D : Map Gene to Disease2018
BioCentury BCIQEMX2
ClinGenEMX2 (curated)
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2018
Chemical/Pharm GKB GenePA27778
Clinical trialEMX2
Miscellaneous
canSAR (ICR)EMX2 (select the gene name)
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEMX2
EVEXEMX2
GoPubMedEMX2
iHOPEMX2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Feb 28 13:11:15 CET 2018
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