Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

EN2 (engrailed homeobox 2)

Identity

Other alias-
HGNC (Hugo) EN2
LocusID (NCBI) 2020
Atlas_Id 46279
Location 7q36.3  [Link to chromosome band 7q36]
Location_base_pair Starts at 155250824 and ends at 155257526 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EN2   3343
Cards
Entrez_Gene (NCBI)EN2  2020  engrailed homeobox 2
Aliases
GeneCards (Weizmann)EN2
Ensembl hg19 (Hinxton)ENSG00000164778 [Gene_View]  chr7:155250824-155257526 [Contig_View]  EN2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000164778 [Gene_View]  chr7:155250824-155257526 [Contig_View]  EN2 [Vega]
ICGC DataPortalENSG00000164778
TCGA cBioPortalEN2
AceView (NCBI)EN2
Genatlas (Paris)EN2
WikiGenes2020
SOURCE (Princeton)EN2
Genetics Home Reference (NIH)EN2
Genomic and cartography
GoldenPath hg19 (UCSC)EN2  -     chr7:155250824-155257526 +  7q36.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)EN2  -     7q36.3   [Description]    (hg38-Dec_2013)
EnsemblEN2 - 7q36.3 [CytoView hg19]  EN2 - 7q36.3 [CytoView hg38]
Mapping of homologs : NCBIEN2 [Mapview hg19]  EN2 [Mapview hg38]
OMIM131310   
Gene and transcription
Genbank (Entrez)BC104970 BC104972 H16179
RefSeq transcript (Entrez)NM_001427
RefSeq genomic (Entrez)NC_000007 NC_018918 NG_007124 NT_007933 NW_004929334
Consensus coding sequences : CCDS (NCBI)EN2
Cluster EST : UnigeneHs.134989 [ NCBI ]
CGAP (NCI)Hs.134989
Alternative Splicing GalleryENSG00000164778
Gene ExpressionEN2 [ NCBI-GEO ]   EN2 [ EBI - ARRAY_EXPRESS ]   EN2 [ SEEK ]   EN2 [ MEM ]
Gene Expression Viewer (FireBrowse)EN2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2020
GTEX Portal (Tissue expression)EN2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP19622   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP19622  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP19622
Splice isoforms : SwissVarP19622
PhosPhoSitePlusP19622
Domaine pattern : Prosite (Expaxy)ENGRAILED (PS00033)    HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-engrailed_C-terminal    Homeobox_CS    Homeobox_dom    Homeobox_metazoa    Homeodomain-like    Homeodomain_engrailed    Homoebox-engrailed_CS   
Domain families : Pfam (Sanger)Engrail_1_C_sig (PF10525)    Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam10525    pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)EN2
DMDM Disease mutations2020
Blocks (Seattle)EN2
SuperfamilyP19622
Human Protein AtlasENSG00000164778
Peptide AtlasP19622
HPRD08836
IPIIPI00020031   
Protein Interaction databases
DIP (DOE-UCLA)P19622
IntAct (EBI)P19622
FunCoupENSG00000164778
BioGRIDEN2
STRING (EMBL)EN2
ZODIACEN2
Ontologies - Pathways
QuickGOP19622
Ontology : AmiGOnucleus  multicellular organism development  membrane  midbrain development  hindbrain development  negative regulation of neuron apoptotic process  sequence-specific DNA binding  positive regulation of transcription from RNA polymerase II promoter  neuron development  embryonic brain development  
Ontology : EGO-EBInucleus  multicellular organism development  membrane  midbrain development  hindbrain development  negative regulation of neuron apoptotic process  sequence-specific DNA binding  positive regulation of transcription from RNA polymerase II promoter  neuron development  embryonic brain development  
NDEx NetworkEN2
Atlas of Cancer Signalling NetworkEN2
Wikipedia pathwaysEN2
Orthology - Evolution
OrthoDB2020
GeneTree (enSembl)ENSG00000164778
Phylogenetic Trees/Animal Genes : TreeFamEN2
HOVERGENP19622
HOGENOMP19622
Homologs : HomoloGeneEN2
Homology/Alignments : Family Browser (UCSC)EN2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEN2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EN2
dbVarEN2
ClinVarEN2
1000_GenomesEN2 
Exome Variant ServerEN2
ExAC (Exome Aggregation Consortium)EN2 (select the gene name)
Genetic variants : HAPMAP2020
Genomic Variants (DGV)EN2 [DGVbeta]
DECIPHER (Syndromes)7:155250824-155257526  ENSG00000164778
CONAN: Copy Number AnalysisEN2 
Mutations
ICGC Data PortalEN2 
TCGA Data PortalEN2 
Broad Tumor PortalEN2
OASIS PortalEN2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEN2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEN2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EN2
DgiDB (Drug Gene Interaction Database)EN2
DoCM (Curated mutations)EN2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EN2 (select a term)
intoGenEN2
Cancer3DEN2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM131310   
Orphanet
MedgenEN2
Genetic Testing Registry EN2
NextProtP19622 [Medical]
TSGene2020
GENETestsEN2
Huge Navigator EN2 [HugePedia]
snp3D : Map Gene to Disease2020
BioCentury BCIQEN2
ClinGenEN2 (curated)
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2020
Chemical/Pharm GKB GenePA27780
Clinical trialEN2
Miscellaneous
canSAR (ICR)EN2 (select the gene name)
Probes
Litterature
PubMed47 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEN2
EVEXEN2
GoPubMedEN2
iHOPEN2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:00:06 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.