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ENDOG (endonuclease G)

Identity

Other alias-
HGNC (Hugo) ENDOG
LocusID (NCBI) 2021
Atlas_Id 43940
Location 9q34.11  [Link to chromosome band 9q34]
Location_base_pair Starts at 131580779 and ends at 131584955 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ENDOG   3346
Cards
Entrez_Gene (NCBI)ENDOG  2021  endonuclease G
Aliases
GeneCards (Weizmann)ENDOG
Ensembl hg19 (Hinxton)ENSG00000167136 [Gene_View]  chr9:131580779-131584955 [Contig_View]  ENDOG [Vega]
Ensembl hg38 (Hinxton)ENSG00000167136 [Gene_View]  chr9:131580779-131584955 [Contig_View]  ENDOG [Vega]
ICGC DataPortalENSG00000167136
TCGA cBioPortalENDOG
AceView (NCBI)ENDOG
Genatlas (Paris)ENDOG
WikiGenes2021
SOURCE (Princeton)ENDOG
Genetics Home Reference (NIH)ENDOG
Genomic and cartography
GoldenPath hg19 (UCSC)ENDOG  -     chr9:131580779-131584955 +  9q34.11   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ENDOG  -     9q34.11   [Description]    (hg38-Dec_2013)
EnsemblENDOG - 9q34.11 [CytoView hg19]  ENDOG - 9q34.11 [CytoView hg38]
Mapping of homologs : NCBIENDOG [Mapview hg19]  ENDOG [Mapview hg38]
OMIM600440   
Gene and transcription
Genbank (Entrez)AK130973 BC004922 BC016351 X79444
RefSeq transcript (Entrez)NM_004435
RefSeq genomic (Entrez)NC_000009 NC_018920 NT_008470 NW_004929366
Consensus coding sequences : CCDS (NCBI)ENDOG
Cluster EST : UnigeneHs.745161 [ NCBI ]
CGAP (NCI)Hs.745161
Alternative Splicing GalleryENSG00000167136
Gene ExpressionENDOG [ NCBI-GEO ]   ENDOG [ EBI - ARRAY_EXPRESS ]   ENDOG [ SEEK ]   ENDOG [ MEM ]
Gene Expression Viewer (FireBrowse)ENDOG [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2021
GTEX Portal (Tissue expression)ENDOG
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14249   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14249  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14249
Splice isoforms : SwissVarQ14249
Catalytic activity : Enzyme3.1.30.- [ Enzyme-Expasy ]   3.1.30.-3.1.30.- [ IntEnz-EBI ]   3.1.30.- [ BRENDA ]   3.1.30.- [ KEGG ]   
PhosPhoSitePlusQ14249
Domaine pattern : Prosite (Expaxy)NUCLEASE_NON_SPEC (PS01070)   
Domains : Interpro (EBI)DNA/RNA_endonuclease_AS    DNA/RNA_non-sp_Endonuclease    Extracellular_endonuc_su_A   
Domain families : Pfam (Sanger)Endonuclease_NS (PF01223)   
Domain families : Pfam (NCBI)pfam01223   
Domain families : Smart (EMBL)Endonuclease_NS (SM00892)  NUC (SM00477)  
Conserved Domain (NCBI)ENDOG
DMDM Disease mutations2021
Blocks (Seattle)ENDOG
SuperfamilyQ14249
Human Protein AtlasENSG00000167136
Peptide AtlasQ14249
HPRD02704
IPIIPI00290614   
Protein Interaction databases
DIP (DOE-UCLA)Q14249
IntAct (EBI)Q14249
FunCoupENSG00000167136
BioGRIDENDOG
STRING (EMBL)ENDOG
ZODIACENDOG
Ontologies - Pathways
QuickGOQ14249
Ontology : AmiGOin utero embryonic development  nucleic acid binding  endonuclease activity  deoxyribonuclease activity  protein binding  nucleus  mitochondrion  cytosol  apoptotic DNA fragmentation  DNA recombination  aging  response to mechanical stimulus  response to estradiol  response to tumor necrosis factor  neuron death in response to oxidative stress  perikaryon  response to antibiotic  metal ion binding  cellular response to calcium ion  cellular response to glucose stimulus  cellular response to hypoxia  positive regulation of hydrogen peroxide-mediated programmed cell death  positive regulation of apoptotic DNA fragmentation  
Ontology : EGO-EBIin utero embryonic development  nucleic acid binding  endonuclease activity  deoxyribonuclease activity  protein binding  nucleus  mitochondrion  cytosol  apoptotic DNA fragmentation  DNA recombination  aging  response to mechanical stimulus  response to estradiol  response to tumor necrosis factor  neuron death in response to oxidative stress  perikaryon  response to antibiotic  metal ion binding  cellular response to calcium ion  cellular response to glucose stimulus  cellular response to hypoxia  positive regulation of hydrogen peroxide-mediated programmed cell death  positive regulation of apoptotic DNA fragmentation  
Pathways : BIOCARTAApoptotic DNA fragmentation and tissue homeostasis [Genes]    Role of Mitochondria in Apoptotic Signaling [Genes]   
Pathways : KEGGApoptosis   
NDEx NetworkENDOG
Atlas of Cancer Signalling NetworkENDOG
Wikipedia pathwaysENDOG
Orthology - Evolution
OrthoDB2021
GeneTree (enSembl)ENSG00000167136
Phylogenetic Trees/Animal Genes : TreeFamENDOG
HOVERGENQ14249
HOGENOMQ14249
Homologs : HomoloGeneENDOG
Homology/Alignments : Family Browser (UCSC)ENDOG
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerENDOG [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ENDOG
dbVarENDOG
ClinVarENDOG
1000_GenomesENDOG 
Exome Variant ServerENDOG
ExAC (Exome Aggregation Consortium)ENDOG (select the gene name)
Genetic variants : HAPMAP2021
Genomic Variants (DGV)ENDOG [DGVbeta]
DECIPHER (Syndromes)9:131580779-131584955  ENSG00000167136
CONAN: Copy Number AnalysisENDOG 
Mutations
ICGC Data PortalENDOG 
TCGA Data PortalENDOG 
Broad Tumor PortalENDOG
OASIS PortalENDOG [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICENDOG  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDENDOG
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch ENDOG
DgiDB (Drug Gene Interaction Database)ENDOG
DoCM (Curated mutations)ENDOG (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ENDOG (select a term)
intoGenENDOG
Cancer3DENDOG(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600440   
Orphanet
MedgenENDOG
Genetic Testing Registry ENDOG
NextProtQ14249 [Medical]
TSGene2021
GENETestsENDOG
Huge Navigator ENDOG [HugePedia]
snp3D : Map Gene to Disease2021
BioCentury BCIQENDOG
ClinGenENDOG
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2021
Chemical/Pharm GKB GenePA27783
Clinical trialENDOG
Miscellaneous
canSAR (ICR)ENDOG (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineENDOG
EVEXENDOG
GoPubMedENDOG
iHOPENDOG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:04:42 CET 2017

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