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ENDOV (endonuclease V)

Identity

Alias_symbol (synonym)FLJ35220
Other alias-
HGNC (Hugo) ENDOV
LocusID (NCBI) 284131
Atlas_Id 52217
Location 17q25.3  [Link to chromosome band 17q25]
Location_base_pair Starts at 80415167 and ends at 80438084 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ENDOV (17q25.3) / IKZF3 (17q12)ENDOV (17q25.3) / SLC26A11 (17q25.3)ENDOV (17q25.3) / TMEM104 (17q25.1)
USP43 (17p13.1) / ENDOV (17q25.3)ENDOV 17q25.3 / IKZF3 17q12ENDOV 17q25.3 / SLC26A11 17q25.3
ENDOV 17q25.3 / TMEM104 17q25.1USP43 17p13.1 / ENDOV 17q25.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ENDOV   26640
Cards
Entrez_Gene (NCBI)ENDOV  284131  endonuclease V
Aliases
GeneCards (Weizmann)ENDOV
Ensembl hg19 (Hinxton)ENSG00000173818 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173818 [Gene_View]  chr17:80415167-80438084 [Contig_View]  ENDOV [Vega]
ICGC DataPortalENSG00000173818
TCGA cBioPortalENDOV
AceView (NCBI)ENDOV
Genatlas (Paris)ENDOV
WikiGenes284131
SOURCE (Princeton)ENDOV
Genetics Home Reference (NIH)ENDOV
Genomic and cartography
GoldenPath hg38 (UCSC)ENDOV  -     chr17:80415167-80438084 +  17q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ENDOV  -     17q25.3   [Description]    (hg19-Feb_2009)
EnsemblENDOV - 17q25.3 [CytoView hg19]  ENDOV - 17q25.3 [CytoView hg38]
Mapping of homologs : NCBIENDOV [Mapview hg19]  ENDOV [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK056045 AK092539 AK096344 AK096802 AK123689
RefSeq transcript (Entrez)NM_001164637 NM_001164638 NM_173627
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ENDOV
Cluster EST : UnigeneHs.728933 [ NCBI ]
CGAP (NCI)Hs.728933
Alternative Splicing GalleryENSG00000173818
Gene ExpressionENDOV [ NCBI-GEO ]   ENDOV [ EBI - ARRAY_EXPRESS ]   ENDOV [ SEEK ]   ENDOV [ MEM ]
Gene Expression Viewer (FireBrowse)ENDOV [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)284131
GTEX Portal (Tissue expression)ENDOV
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N8Q3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N8Q3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N8Q3
Splice isoforms : SwissVarQ8N8Q3
Catalytic activity : Enzyme3.1.26.- [ Enzyme-Expasy ]   3.1.26.-3.1.26.- [ IntEnz-EBI ]   3.1.26.- [ BRENDA ]   3.1.26.- [ KEGG ]   
PhosPhoSitePlusQ8N8Q3
Domains : Interpro (EBI)Endonuclease-V   
Domain families : Pfam (Sanger)Endonuclease_5 (PF04493)   
Domain families : Pfam (NCBI)pfam04493   
Conserved Domain (NCBI)ENDOV
DMDM Disease mutations284131
Blocks (Seattle)ENDOV
PDB (SRS)4NSP   
PDB (PDBSum)4NSP   
PDB (IMB)4NSP   
PDB (RSDB)4NSP   
Structural Biology KnowledgeBase4NSP   
SCOP (Structural Classification of Proteins)4NSP   
CATH (Classification of proteins structures)4NSP   
SuperfamilyQ8N8Q3
Human Protein AtlasENSG00000173818
Peptide AtlasQ8N8Q3
HPRD08758
IPIIPI00167531   IPI00902876   IPI00418341   IPI00384512   IPI00446404   IPI00973752   IPI00974330   IPI00974453   IPI00973786   IPI00983573   IPI01009744   IPI00984725   IPI00985221   
Protein Interaction databases
DIP (DOE-UCLA)Q8N8Q3
IntAct (EBI)Q8N8Q3
FunCoupENSG00000173818
BioGRIDENDOV
STRING (EMBL)ENDOV
ZODIACENDOV
Ontologies - Pathways
QuickGOQ8N8Q3
Ontology : AmiGOmagnesium ion binding  magnesium ion binding  DNA binding  single-stranded RNA binding  nucleolus  cytoplasm  DNA repair  endodeoxyribonuclease activity, producing 5'-phosphomonoesters  endodeoxyribonuclease activity, producing 5'-phosphomonoesters  endoribonuclease activity, producing 5'-phosphomonoesters  RNA phosphodiester bond hydrolysis, endonucleolytic  
Ontology : EGO-EBImagnesium ion binding  magnesium ion binding  DNA binding  single-stranded RNA binding  nucleolus  cytoplasm  DNA repair  endodeoxyribonuclease activity, producing 5'-phosphomonoesters  endodeoxyribonuclease activity, producing 5'-phosphomonoesters  endoribonuclease activity, producing 5'-phosphomonoesters  RNA phosphodiester bond hydrolysis, endonucleolytic  
NDEx NetworkENDOV
Atlas of Cancer Signalling NetworkENDOV
Wikipedia pathwaysENDOV
Orthology - Evolution
OrthoDB284131
GeneTree (enSembl)ENSG00000173818
Phylogenetic Trees/Animal Genes : TreeFamENDOV
HOVERGENQ8N8Q3
HOGENOMQ8N8Q3
Homologs : HomoloGeneENDOV
Homology/Alignments : Family Browser (UCSC)ENDOV
Gene fusions - Rearrangements
Fusion : MitelmanENDOV/IKZF3 [17q25.3/17q12]  
Fusion : MitelmanENDOV/SLC26A11 [17q25.3/17q25.3]  [t(17;17)(q25;q25)]  
Fusion : MitelmanENDOV/TMEM104 [17q25.3/17q25.1]  [t(17;17)(q25;q25)]  
Fusion : MitelmanUSP43/ENDOV [17p13.1/17q25.3]  [t(17;17)(p13;q25)]  
Fusion: TCGAENDOV 17q25.3 IKZF3 17q12 BRCA
Fusion: TCGAENDOV 17q25.3 SLC26A11 17q25.3 BRCA
Fusion: TCGAENDOV 17q25.3 TMEM104 17q25.1 KIRC
Fusion: TCGAUSP43 17p13.1 ENDOV 17q25.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerENDOV [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ENDOV
dbVarENDOV
ClinVarENDOV
1000_GenomesENDOV 
Exome Variant ServerENDOV
ExAC (Exome Aggregation Consortium)ENDOV (select the gene name)
Genetic variants : HAPMAP284131
Genomic Variants (DGV)ENDOV [DGVbeta]
DECIPHERENDOV [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisENDOV 
Mutations
ICGC Data PortalENDOV 
TCGA Data PortalENDOV 
Broad Tumor PortalENDOV
OASIS PortalENDOV [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICENDOV  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDENDOV
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ENDOV
DgiDB (Drug Gene Interaction Database)ENDOV
DoCM (Curated mutations)ENDOV (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ENDOV (select a term)
intoGenENDOV
Cancer3DENDOV(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenENDOV
Genetic Testing Registry ENDOV
NextProtQ8N8Q3 [Medical]
TSGene284131
GENETestsENDOV
Target ValidationENDOV
Huge Navigator ENDOV [HugePedia]
snp3D : Map Gene to Disease284131
BioCentury BCIQENDOV
ClinGenENDOV
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD284131
Chemical/Pharm GKB GenePA166048970
Clinical trialENDOV
Miscellaneous
canSAR (ICR)ENDOV (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineENDOV
EVEXENDOV
GoPubMedENDOV
iHOPENDOV
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:32:36 CEST 2017

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