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ENPEP (glutamyl aminopeptidase (aminopeptidase A))

Identity

Other namesAPA
CD249
gp160
HGNC (Hugo) ENPEP
LocusID (NCBI) 2028
Location 4q25
Location_base_pair Starts at 111397229 and ends at 111484493 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ENPEP   3355
Cards
Entrez_Gene (NCBI)ENPEP  2028  glutamyl aminopeptidase (aminopeptidase A)
GeneCards (Weizmann)ENPEP
Ensembl (Hinxton) [Gene_View]  chr4:111397229-111484493 [Contig_View]  ENPEP [Vega]
cBioPortalENPEP
AceView (NCBI)ENPEP
Genatlas (Paris)ENPEP
WikiGenes2028
SOURCE (Princeton)NM_001977
Genomic and cartography
GoldenPath (UCSC)ENPEP  -  4q25   chr4:111397229-111484493 +  4q25   [Description]    (hg19-Feb_2009)
EnsemblENPEP - 4q25 [CytoView]
Mapping of homologs : NCBIENPEP [Mapview]
OMIM138297   
Gene and transcription
Genbank (Entrez)AI640493 AK313412 AL568777 AM888273 AM888274
RefSeq transcript (Entrez)NM_001977
RefSeq genomic (Entrez)AC_000136 NC_000004 NC_018915 NT_016354 NW_001838915 NW_004929320
Consensus coding sequences : CCDS (NCBI)ENPEP
Cluster EST : UnigeneHs.435765 [ NCBI ]
CGAP (NCI)Hs.435765
Alternative Splicing : Fast-db (Paris)GSHG0022789
Gene ExpressionENPEP [ NCBI-GEO ]     ENPEP [ SEEK ]   ENPEP [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ07075 (Uniprot)
NextProtQ07075  [Medical]
With graphics : InterProQ07075
Splice isoforms : SwissVarQ07075 (Swissvar)
Catalytic activity : Enzyme3.4.11.7 [ Enzyme-Expasy ]   3.4.11.73.4.11.7 [ IntEnz-EBI ]   3.4.11.7 [ BRENDA ]   3.4.11.7 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)ZINC_PROTEASE (PS00142)   
Domains : Interpro (EBI)ERAP1-like_C_dom [organisation]   Peptidase_M1 [organisation]   Peptidase_M1_N [organisation]  
Related proteins : CluSTrQ07075
Domain families : Pfam (Sanger)ERAP1_C (PF11838)    Peptidase_M1 (PF01433)   
Domain families : Pfam (NCBI)pfam11838    pfam01433   
DMDM Disease mutations2028
Blocks (Seattle)Q07075
PDB (SRS)4KX7    4KX8    4KX9    4KXA    4KXB    4KXC    4KXD   
PDB (PDBSum)4KX7    4KX8    4KX9    4KXA    4KXB    4KXC    4KXD   
PDB (IMB)4KX7    4KX8    4KX9    4KXA    4KXB    4KXC    4KXD   
PDB (RSDB)4KX7    4KX8    4KX9    4KXA    4KXB    4KXC    4KXD   
Peptide AtlasQ07075
HPRD08848
IPIIPI00014375   IPI00967998   
Protein Interaction databases
DIP (DOE-UCLA)Q07075
IntAct (EBI)Q07075
BioGRIDENPEP
InParanoidQ07075
Interologous Interaction database Q07075
IntegromeDBENPEP
STRING (EMBL)ENPEP
Ontologies - Pathways
Ontology : AmiGOangiogenesis  angiotensin maturation  angiotensin catabolic process in blood  regulation of systemic arterial blood pressure by renin-angiotensin  regulation of systemic arterial blood pressure by renin-angiotensin  aminopeptidase activity  lysosomal membrane  plasma membrane  integral component of plasma membrane  brush border  proteolysis  cell-cell signaling  metallopeptidase activity  zinc ion binding  cell proliferation  cell proliferation  external side of plasma membrane  apical plasma membrane  cell migration  cytoplasmic vesicle  glomerulus development  cellular protein metabolic process  apical part of cell  metalloaminopeptidase activity  metalloaminopeptidase activity  extracellular vesicular exosome  
Ontology : EGO-EBIangiogenesis  angiotensin maturation  angiotensin catabolic process in blood  regulation of systemic arterial blood pressure by renin-angiotensin  regulation of systemic arterial blood pressure by renin-angiotensin  aminopeptidase activity  lysosomal membrane  plasma membrane  integral component of plasma membrane  brush border  proteolysis  cell-cell signaling  metallopeptidase activity  zinc ion binding  cell proliferation  cell proliferation  external side of plasma membrane  apical plasma membrane  cell migration  cytoplasmic vesicle  glomerulus development  cellular protein metabolic process  apical part of cell  metalloaminopeptidase activity  metalloaminopeptidase activity  extracellular vesicular exosome  
Pathways : KEGGRenin-angiotensin system   
Protein Interaction DatabaseENPEP
Wikipedia pathwaysENPEP
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)ENPEP
snp3D : Map Gene to Disease2028
SNP (GeneSNP Utah)ENPEP
SNP : HGBaseENPEP
Genetic variants : HAPMAPENPEP
Exome VariantENPEP
1000_GenomesENPEP 
Somatic Mutations in Cancer : COSMICENPEP 
CONAN: Copy Number AnalysisENPEP 
Mutations and Diseases : HGMDENPEP
Mutations and Diseases : intOGenENPEP
Genomic VariantsENPEP  ENPEP [DGVbeta]
dbVarENPEP
ClinVarENPEP
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM138297   
MedgenENPEP
GENETestsENPEP
Disease Genetic AssociationENPEP
Huge Navigator ENPEP [HugePedia]  ENPEP [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneENPEP
Homology/Alignments : Family Browser (UCSC)ENPEP
Phylogenetic Trees/Animal Genes : TreeFamENPEP
Chemical/Protein Interactions : CTD2028
Chemical/Pharm GKB GenePA27790
Clinical trialENPEP
Other databases
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
CoreMineENPEP
iHOPENPEP
OncoSearchENPEP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 16:45:50 CEST 2014

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