Atlas of Genetics and Cytogenetics in Oncology and Haematology

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ENPP3 (ectonucleotide pyrophosphatase/phosphodiesterase 3)

Identity

Other namesB10
CD203c
NPP3
PD-IBETA
PDNP3
HGNC (Hugo) ENPP3
LocusID (NCBI) 5169
Location 6q23.2
Location_base_pair Starts at 131958442 and ends at 132068550 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ENPP3   3358
Entrez_Gene (NCBI)ENPP3  5169  ectonucleotide pyrophosphatase/phosphodiesterase 3
Cards
GeneCards (Weizmann)ENPP3
Ensembl (Hinxton)ENSG00000154269 [Gene_View]  chr6:131958442-132068550 [Contig_View]  ENPP3 [Vega]
AceView (NCBI)ENPP3
Genatlas (Paris)ENPP3
SOURCE (Stanford)NM_005021
Genomic and cartography
GoldenPath (UCSC)ENPP3  -  6q23.2   chr6:131958442-132068550 +  6q23.2   [Description]    (hg19-Feb_2009)
EnsemblENPP3 - 6q23.2 [CytoView]
Mapping of homologs : NCBIENPP3 [Mapview]
OMIM602182   
Gene and transcription
Genbank (Entrez)AK024899 AK226107 AK292903 AK296080 AK309080
RefSeq transcript (SRS)NM_005021
RefSeq transcript (Entrez)NM_005021
RefSeq genomic (SRS)AC_000138 NC_000006 NC_018917 NT_025741 NW_001838990 NW_004078028
RefSeq genomic (Entrez)AC_000138 NC_000006 NC_018917 NT_025741 NW_001838990 NW_004078028
Consensus coding sequences : CCDS (NCBI)ENPP3
Cluster EST : UnigeneHs.486489 [ SRS ] Hs.486489 [ NCBI ]
CGAP (NCI)Hs.486489
Alternative Splicing : Fast-db (Paris)GSHG0026037
Alternative Splicing GalleryENSG00000154269
Gene ExpressionENPP3 [ NCBI-GEO ]   ENPP3 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14638 (SRS) O14638 (Uniprot)
NextProtO14638
With graphics : InterProO14638
Splice isoforms : SwissVarO14638(Swissvar)
Domaine pattern : Prosite (SRS)SMB_1 (PS00524)    SMB_2 (PS50958)   
Domaine pattern : Prosite (Expaxy)SMB_1 (PS00524)    SMB_2 (PS50958)   
Domains : Interpro (SRS)Alkaline_Pase-like_a/b/a    Alkaline_phosphatase_core    DNA/RNA_non-sp_Endonuclease    E-NPP    Extracellular_endonuc_su_A    Phosphodiest/P_Trfase    Somatomedin_B_dom   
Domains : Interpro (EBI)Alkaline_Pase-like_a/b/a    Alkaline_phosphatase_core    DNA/RNA_non-sp_Endonuclease    E-NPP    Extracellular_endonuc_su_A    Phosphodiest/P_Trfase    Somatomedin_B_dom   
Related proteins : CluSTrO14638
Domain families : Pfam (SRS)Endonuclease_NS (PF01223)    Phosphodiest (PF01663)    Somatomedin_B (PF01033)   
Domain families : Pfam (Sanger)Endonuclease_NS (PF01223)    Phosphodiest (PF01663)    Somatomedin_B (PF01033)   
Domain families : Pfam (NCBI)pfam01223    pfam01663    pfam01033   
Domain families : Smart (EMBL)Endonuclease_NS (SM00892)  NUC (SM00477)  SO (SM00201)  
DMDM5169
Blocks (Seattle)O14638
Human Protein AtlasENSG00000154269
HPRD03715
IPIIPI00020999   IPI00478342   IPI01014293   IPI00924646   IPI00896431   
Protein Interaction databases
DIP (DOE-UCLA)O14638
IntAct (EBI)O14638
FunCoupENSG00000154269
REACTOMEENPP3
Protein Interaction Database5169
BioGRIDENPP3
InParanoidO14638
Interologous Interaction database O14638
IntegromeDBENPP3
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)ENPP3
SNP (GeneSNP Utah)ENPP3
SNP : HGBaseENPP3
Genetic variants : HAPMAPENPP3
Somatic Mutations in Cancer : COSMICENPP3 
CONAN: Copy Number AnalysisENPP3 
Mutations and Diseases : HGMDENPP3
OMIM602182   
GENETests602182   
Disease Genetic AssociationENPP3
Huge Navigator ENPP3 [HugePedia]  ENPP3 [HugeCancerGEM]
Genomic VariantsENPP3  ENPP3 [DGVbeta]
snp3D : Map Gene to Disease5169
General knowledge
Homologs : HomoloGeneENPP3
Homology/Alignments : Family Browser (UCSC)ENPP3
Phylogenetic Trees/Animal Genes : TreeFamENPP3
Catalytic activity : Enzyme3.1.4.1 [ Enzyme-Expasy ]   3.1.4.1 [ Enzyme-SRS ]   3.1.4.1 [ IntEnz-EBI ]   3.1.4.1 [ BRENDA ]   3.1.4.1 [ KEGG ]   
Chemical/Protein Interactions : CTD5169
Chemical/Pharm GKB GenePA27793
Clinical trialENPP3
Cancer Resource (Charite)ENSG00000154269
Ontology : AmiGOnucleic acid binding  phosphodiesterase I activity  nucleotide diphosphatase activity  scavenger receptor activity  extracellular region  integral to plasma membrane  phosphate-containing compound metabolic process  immune response  nucleoside triphosphate catabolic process  polysaccharide binding  inorganic diphosphate transport  NADH pyrophosphatase activity  metal ion binding  nucleoside-triphosphate diphosphatase activity  perinuclear region of cytoplasm  
Ontology : EGO-EBInucleic acid binding  phosphodiesterase I activity  nucleotide diphosphatase activity  scavenger receptor activity  extracellular region  integral to plasma membrane  phosphate-containing compound metabolic process  immune response  nucleoside triphosphate catabolic process  polysaccharide binding  inorganic diphosphate transport  NADH pyrophosphatase activity  metal ion binding  nucleoside-triphosphate diphosphatase activity  perinuclear region of cytoplasm  
Pathways : KEGGPurine metabolismNicotinate and nicotinamide metabolismStarch and sucrose metabolismRiboflavin metabolismPantothenate and CoA biosynthesis
Other databases
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
PubGeneENPP3
iHOPENPP3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:21:15 CEST 2013
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