ENTPD6 (ectonucleoside triphosphate diphosphohydrolase 6)

2014-11-01  

Identity

HGNC
LOCATION
20p11.21
LOCUSID
ALIAS
CD39L2,IL-6SAG,IL6ST2,NTPDase-6,dJ738P15.3
FUSION GENES

Other Information

Locus ID:

NCBI: 955
MIM: 603160
HGNC: 3368
Ensembl: ENSG00000197586

Variants:

dbSNP: 955
ClinVar: 955
TCGA: ENSG00000197586
COSMIC: ENTPD6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197586ENST00000354989O75354
ENSG00000197586ENST00000360031O75354
ENSG00000197586ENST00000376652O75354
ENSG00000197586ENST00000376666H0Y3D0
ENSG00000197586ENST00000417467Q5QPI7
ENSG00000197586ENST00000418890Q5QPJ7
ENSG00000197586ENST00000425813Q5QPJ3
ENSG00000197586ENST00000427553H0Y5X0
ENSG00000197586ENST00000433259Q5QPI9
ENSG00000197586ENST00000433417H0Y473
ENSG00000197586ENST00000435520Q5QPJ4
ENSG00000197586ENST00000439162Q5QPJ6
ENSG00000197586ENST00000447877H0Y6Q1

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Purine metabolismKEGGko00230
Pyrimidine metabolismKEGGko00240
Purine metabolismKEGGhsa00230
Pyrimidine metabolismKEGGhsa00240
MetabolismREACTOMER-HSA-1430728
Metabolism of nucleotidesREACTOMER-HSA-15869
Phosphate bond hydrolysis by NTPDase proteinsREACTOMER-HSA-8850843

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
145292832003Bacterial expression, characterization, and disulfide bond determination of soluble human NTPDase6 (CD39L2) nucleotidase: implications for structure and function.17
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11

Citation

Dessen P

ENTPD6 (ectonucleoside triphosphate diphosphohydrolase 6)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62846/entpd6