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ENTPD6 (ectonucleoside triphosphate diphosphohydrolase 6 (putative))

Identity

Alias_namesCD39L2
IL6ST2
interleukin 6 signal transducer-2
Alias_symbol (synonym)NTPDase-6
dJ738P15.3
Other aliasIL-6SAG
HGNC (Hugo) ENTPD6
LocusID (NCBI) 955
Atlas_Id 62846
Location 20p11.21  [Link to chromosome band 20p11]
Location_base_pair Starts at 25176339 and ends at 25207360 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CAMTA1 (1p36.31) / ENTPD6 (20p11.21)ENTPD6 (20p11.21) / CGNL1 (15q21.3)ENTPD6 (20p11.21) / ENTPD6 (20p11.21)
ENTPD6 (20p11.21) / MPG (16p13.3)HEYL (1p34.3) / ENTPD6 (20p11.21)MPG (16p13.3) / ENTPD6 (20p11.21)
PYGB (20p11.21) / ENTPD6 (20p11.21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ENTPD6   3368
Cards
Entrez_Gene (NCBI)ENTPD6  955  ectonucleoside triphosphate diphosphohydrolase 6 (putative)
AliasesCD39L2; IL-6SAG; IL6ST2; NTPDase-6; 
dJ738P15.3
GeneCards (Weizmann)ENTPD6
Ensembl hg19 (Hinxton)ENSG00000197586 [Gene_View]  chr20:25176339-25207360 [Contig_View]  ENTPD6 [Vega]
Ensembl hg38 (Hinxton)ENSG00000197586 [Gene_View]  chr20:25176339-25207360 [Contig_View]  ENTPD6 [Vega]
ICGC DataPortalENSG00000197586
TCGA cBioPortalENTPD6
AceView (NCBI)ENTPD6
Genatlas (Paris)ENTPD6
WikiGenes955
SOURCE (Princeton)ENTPD6
Genetics Home Reference (NIH)ENTPD6
Genomic and cartography
GoldenPath hg19 (UCSC)ENTPD6  -     chr20:25176339-25207360 +  20p11.21   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ENTPD6  -     20p11.21   [Description]    (hg38-Dec_2013)
EnsemblENTPD6 - 20p11.21 [CytoView hg19]  ENTPD6 - 20p11.21 [CytoView hg38]
Mapping of homologs : NCBIENTPD6 [Mapview hg19]  ENTPD6 [Mapview hg38]
OMIM603160   
Gene and transcription
Genbank (Entrez)AF039916 AF058296 AK074691 AK094030 AK095708
RefSeq transcript (Entrez)NM_001114089 NM_001247
RefSeq genomic (Entrez)NC_000020 NC_018931 NT_011387 NW_004929416
Consensus coding sequences : CCDS (NCBI)ENTPD6
Cluster EST : UnigeneHs.500375 [ NCBI ]
CGAP (NCI)Hs.500375
Alternative Splicing GalleryENSG00000197586
Gene ExpressionENTPD6 [ NCBI-GEO ]   ENTPD6 [ EBI - ARRAY_EXPRESS ]   ENTPD6 [ SEEK ]   ENTPD6 [ MEM ]
Gene Expression Viewer (FireBrowse)ENTPD6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)955
GTEX Portal (Tissue expression)ENTPD6
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75354   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75354  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75354
Splice isoforms : SwissVarO75354
Catalytic activity : Enzyme3.6.1.6 [ Enzyme-Expasy ]   3.6.1.63.6.1.6 [ IntEnz-EBI ]   3.6.1.6 [ BRENDA ]   3.6.1.6 [ KEGG ]   
PhosPhoSitePlusO75354
Domaine pattern : Prosite (Expaxy)GDA1_CD39_NTPASE (PS01238)   
Domains : Interpro (EBI)GDA1_CD39_NTPase   
Domain families : Pfam (Sanger)GDA1_CD39 (PF01150)   
Domain families : Pfam (NCBI)pfam01150   
Conserved Domain (NCBI)ENTPD6
DMDM Disease mutations955
Blocks (Seattle)ENTPD6
SuperfamilyO75354
Human Protein AtlasENSG00000197586
Peptide AtlasO75354
HPRD16013
IPIIPI00025295   IPI00478478   IPI00513843   IPI00911031   IPI00980485   IPI00514063   IPI00718817   IPI00426005   IPI00639929   IPI00642337   IPI00642831   IPI00514421   IPI01018358   IPI00513942   IPI00644954   IPI00514630   IPI00514953   
Protein Interaction databases
DIP (DOE-UCLA)O75354
IntAct (EBI)O75354
FunCoupENSG00000197586
BioGRIDENTPD6
STRING (EMBL)ENTPD6
ZODIACENTPD6
Ontologies - Pathways
QuickGOO75354
Ontology : AmiGOGolgi membrane  extracellular space  plasma membrane  metabolic process  guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity  cell surface  integral component of membrane  nucleoside-triphosphatase activity  response to magnesium ion  uridine-diphosphatase activity  response to calcium ion  extracellular exosome  
Ontology : EGO-EBIGolgi membrane  extracellular space  plasma membrane  metabolic process  guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity  cell surface  integral component of membrane  nucleoside-triphosphatase activity  response to magnesium ion  uridine-diphosphatase activity  response to calcium ion  extracellular exosome  
Pathways : KEGGPurine metabolism    Pyrimidine metabolism   
NDEx NetworkENTPD6
Atlas of Cancer Signalling NetworkENTPD6
Wikipedia pathwaysENTPD6
Orthology - Evolution
OrthoDB955
GeneTree (enSembl)ENSG00000197586
Phylogenetic Trees/Animal Genes : TreeFamENTPD6
HOVERGENO75354
HOGENOMO75354
Homologs : HomoloGeneENTPD6
Homology/Alignments : Family Browser (UCSC)ENTPD6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerENTPD6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ENTPD6
dbVarENTPD6
ClinVarENTPD6
1000_GenomesENTPD6 
Exome Variant ServerENTPD6
ExAC (Exome Aggregation Consortium)ENTPD6 (select the gene name)
Genetic variants : HAPMAP955
Genomic Variants (DGV)ENTPD6 [DGVbeta]
DECIPHER (Syndromes)20:25176339-25207360  ENSG00000197586
CONAN: Copy Number AnalysisENTPD6 
Mutations
ICGC Data PortalENTPD6 
TCGA Data PortalENTPD6 
Broad Tumor PortalENTPD6
OASIS PortalENTPD6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICENTPD6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDENTPD6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ENTPD6
DgiDB (Drug Gene Interaction Database)ENTPD6
DoCM (Curated mutations)ENTPD6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ENTPD6 (select a term)
intoGenENTPD6
Cancer3DENTPD6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603160   
Orphanet
MedgenENTPD6
Genetic Testing Registry ENTPD6
NextProtO75354 [Medical]
TSGene955
GENETestsENTPD6
Huge Navigator ENTPD6 [HugePedia]
snp3D : Map Gene to Disease955
BioCentury BCIQENTPD6
ClinGenENTPD6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD955
Chemical/Pharm GKB GenePA27803
Clinical trialENTPD6
Miscellaneous
canSAR (ICR)ENTPD6 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineENTPD6
EVEXENTPD6
GoPubMedENTPD6
iHOPENTPD6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:02:56 CET 2017

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