ENY2 (ENY2 transcription and export complex 2 subunit)

2017-10-01  

Identity

HGNC
LOCATION
8q23.1
LOCUSID
ALIAS
DC6,Sus1,e(y)2
FUSION GENES

Other Information

Locus ID:

NCBI: 56943
HGNC: 24449
Ensembl: ENSG00000120533

Variants:

dbSNP: 56943
ClinVar: 56943
TCGA: ENSG00000120533
COSMIC: ENY2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000120533ENST00000339942J3KNT2
ENSG00000120533ENST00000517311E5RJ84
ENSG00000120533ENST00000520147E5RHX8
ENSG00000120533ENST00000521662Q9NPA8
ENSG00000120533ENST00000521688Q9NPA8
ENSG00000120533ENST00000521688A0A024R9D9
ENSG00000120533ENST00000522766E5RI00
ENSG00000120533ENST00000523335E5RHT9

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
Chromatin organizationREACTOMER-HSA-4839726
Chromatin modifying enzymesREACTOMER-HSA-3247509
HATs acetylate histonesREACTOMER-HSA-3214847

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
182069722008A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.157
271329402016ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth.29

Citation

Dessen P

ENY2 (ENY2 transcription and export complex 2 subunit)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57124/eny2