EPB41L2 (erythrocyte membrane protein band 4.1 like 2)

2014-11-01  

Identity

HGNC
LOCATION
6q23.1
LOCUSID
ALIAS
4.1-G,4.1G
FUSION GENES

Other Information

Locus ID:

NCBI: 2037
MIM: 603237
HGNC: 3379
Ensembl: ENSG00000079819

Variants:

dbSNP: 2037
ClinVar: 2037
TCGA: ENSG00000079819
COSMIC: EPB41L2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000079819ENST00000337057O43491
ENSG00000079819ENST00000368128O43491
ENSG00000079819ENST00000392427O43491
ENSG00000079819ENST00000445890O43491
ENSG00000079819ENST00000456097H0Y5B0
ENSG00000079819ENST00000524581Q6R5J7
ENSG00000079819ENST00000525193E9PII3
ENSG00000079819ENST00000525198E9PMG5
ENSG00000079819ENST00000525271O43491
ENSG00000079819ENST00000526983E9PRG1
ENSG00000079819ENST00000527017E9PN54
ENSG00000079819ENST00000527411E9PHY5
ENSG00000079819ENST00000527423E9PMV8
ENSG00000079819ENST00000527659E9PK52
ENSG00000079819ENST00000528282O43491
ENSG00000079819ENST00000529208E9PHY5
ENSG00000079819ENST00000529709E9PQD2
ENSG00000079819ENST00000530481O43491
ENSG00000079819ENST00000530707E9PJP4
ENSG00000079819ENST00000530757Q6ZSX4
ENSG00000079819ENST00000531356E9PQN0
ENSG00000079819ENST00000531410E9PPC9
ENSG00000079819ENST00000532499E9PIG0
ENSG00000079819ENST00000628542E9PHY5
ENSG00000079819ENST00000639623A0A2R8Y5B3

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Neuronal SystemREACTOMER-HSA-112316
Protein-protein interactions at synapsesREACTOMER-HSA-6794362
Interactions of neurexins and neuroligins at synapsesREACTOMER-HSA-6794361

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
201892452010Genome-wide association study of childhood acute lymphoblastic leukemia in Korea.16
151382812004The LFA-1-associated molecule PTA-1 (CD226) on T cells forms a dynamic molecular complex with protein 4.1G and human discs large.13
220032082012Serine phosphorylation of FcγRI cytoplasmic domain directs lipid raft localization and interaction with protein 4.1G.5
180234802008Protein 4.1G binds to a unique motif within the Fc gamma RI cytoplasmic tail.3
232017802013Suppression of adenylyl cyclase-mediated cAMP production by plasma membrane associated cytoskeletal protein 4.1G.0
233545862013Novel mechanism of regulation of protein 4.1G binding properties through Ca2+/calmodulin-mediated structural changes.0
313837682019Activity of Adenylyl Cyclase Type 6 Is Suppressed by Direct Binding of the Cytoskeletal Protein 4.1G.0

Citation

Dessen P

EPB41L2 (erythrocyte membrane protein band 4.1 like 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62854/epb41l2