| BMPR2 (2q33.1) / EPC1 (10p11.22) | DDX24 (14q32.12) / EPC1 (10p11.22) | EPC1 (10p11.22) / ASXL2 (2p23.3) |
|
EPC1 (10p11.22) / BMPR2 (2q33.1) | EPC1 (10p11.22) / PHF1 (6p21.32) | EPC1 (10p11.22) / PTGR2 (14q24.3) |
|
EPC1 (10p11.22) / RBM47 (4p14) | EPC1 (10p11.22) / SNX5 (20p11.23) | EPC1 (10p11.22) / ZEB1 (10p11.22) |
|
LGALS4 (19q13.2) / EPC1 (10p11.22) | EPC1 PHF1 6p21.32 | EPC1 10p11.22 / PTGR2 14q24.3 |
|
| Nomenclature |
HGNC (Hugo) | EPC1 19876 |
| Cards |
Entrez_Gene (NCBI) | EPC1 enhancer of polycomb homolog 1 |
Aliases | Epl1 |
GeneCards (Weizmann) | EPC1 |
Ensembl hg19 (Hinxton) | ENSG00000120616 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000120616 [Gene_View]  ENSG00000120616 [Sequence] chr10:32267716-32347158 [Contig_View] EPC1 [Vega] |
ICGC DataPortal | ENSG00000120616 |
TCGA cBioPortal | EPC1 |
AceView (NCBI) | EPC1 |
Genatlas (Paris) | EPC1 |
SOURCE (Princeton) | EPC1 |
Genetics Home Reference (NIH) | EPC1 |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | EPC1 - chr10:32267716-32347158 - 10p11.22 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | EPC1 - 10p11.22 [Description] (hg19-Feb_2009) |
GoldenPath | EPC1 - 10p11.22 [CytoView hg19] EPC1 - 10p11.22 [CytoView hg38] |
ImmunoBase | ENSG00000120616 |
genome Data Viewer NCBI | EPC1 [Mapview hg19] |
OMIM | 610999 |
| Gene and transcription |
Genbank (Entrez) | AA553969 AF277374 AF286905 AK024329 AK092304 |
RefSeq transcript (Entrez) | NM_001272004 NM_001272019 NM_001282391 NM_001382753 NM_001382754 NM_001382755 NM_001382756 NM_025209 |
RefSeq genomic (Entrez) | |
Consensus coding sequences : CCDS (NCBI) | EPC1 |
Alternative Splicing Gallery | ENSG00000120616 |
Gene Expression | EPC1 [ NCBI-GEO ] EPC1 [ EBI - ARRAY_EXPRESS ]
EPC1 [ SEEK ] EPC1 [ MEM ] |
Gene Expression Viewer (FireBrowse) | EPC1 [ Firebrowse - Broad ] |
Genevisible | Expression of EPC1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 80314 |
GTEX Portal (Tissue expression) | EPC1 |
Human Protein Atlas | ENSG00000120616-EPC1 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | Q9H2F5 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | Q9H2F5 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | Q9H2F5 |
Splice isoforms : SwissVar | Q9H2F5 |
PhosPhoSitePlus | Q9H2F5 |
Domains : Interpro (EBI) | Enhancer_polycomb Enhancer_polycomb-like_N Enhancer_polycomb_C |
Domain families : Pfam (Sanger) | E_Pc_C (PF06752) EPL1 (PF10513) |
Domain families : Pfam (NCBI) | pfam06752 pfam10513 |
Conserved Domain (NCBI) | EPC1 |
Blocks (Seattle) | EPC1 |
PDB (RSDB) | 6NFX |
PDB Europe | 6NFX |
PDB (PDBSum) | 6NFX |
PDB (IMB) | 6NFX |
Structural Biology KnowledgeBase | 6NFX |
SCOP (Structural Classification of Proteins) | 6NFX |
CATH (Classification of proteins structures) | 6NFX |
Superfamily | Q9H2F5 |
Human Protein Atlas [tissue] | ENSG00000120616-EPC1 [tissue] |
Peptide Atlas | Q9H2F5 |
HPRD | 09941 |
IPI | IPI00018823 IPI00302085 IPI00552203 |
| Protein Interaction databases |
DIP (DOE-UCLA) | Q9H2F5 |
IntAct (EBI) | Q9H2F5 |
BioGRID | EPC1 |
STRING (EMBL) | EPC1 |
ZODIAC | EPC1 |
| Ontologies - Pathways |
QuickGO | Q9H2F5 |
Ontology : AmiGO | negative regulation of transcription by RNA polymerase II histone acetyltransferase activity histone acetyltransferase activity protein binding nucleus nucleoplasm nucleoplasm transcription, DNA-templated regulation of transcription by RNA polymerase II nuclear body nuclear membrane Piccolo NuA4 histone acetyltransferase complex Piccolo NuA4 histone acetyltransferase complex NuA4 histone acetyltransferase complex vascular smooth muscle cell differentiation regulation of growth histone H4 acetylation histone H2A acetylation negative regulation of gene expression, epigenetic negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II negative regulation of G0 to G1 transition |
Ontology : EGO-EBI | negative regulation of transcription by RNA polymerase II histone acetyltransferase activity histone acetyltransferase activity protein binding nucleus nucleoplasm nucleoplasm transcription, DNA-templated regulation of transcription by RNA polymerase II nuclear body nuclear membrane Piccolo NuA4 histone acetyltransferase complex Piccolo NuA4 histone acetyltransferase complex NuA4 histone acetyltransferase complex vascular smooth muscle cell differentiation regulation of growth histone H4 acetylation histone H2A acetylation negative regulation of gene expression, epigenetic negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II negative regulation of G0 to G1 transition |
NDEx Network | EPC1 |
Atlas of Cancer Signalling Network | EPC1 |
Wikipedia pathways | EPC1 |
| Orthology - Evolution |
OrthoDB | 80314 |
GeneTree (enSembl) | ENSG00000120616 |
Phylogenetic Trees/Animal Genes : TreeFam | EPC1 |
HOGENOM | Q9H2F5 |
Homologs : HomoloGene | EPC1 |
Homology/Alignments : Family Browser (UCSC) | EPC1 |
| Gene fusions - Rearrangements |
Fusion : Mitelman | EPC1/ASXL2 [10p11.22/2p23.3]   |
Fusion : Mitelman | EPC1/PHF1 [10p11.22/6p21.32]   |
Fusion : Mitelman | EPC1/PTGR2 [10p11.22/14q24.3]   |
Fusion Portal | EPC1 10p11.22 PTGR2 14q24.3 BRCA |
Fusion : Quiver | EPC1 |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | EPC1 [hg38] |
dbVar | EPC1 |
ClinVar | EPC1 |
Monarch | EPC1 |
1000_Genomes | EPC1 |
Exome Variant Server | EPC1 |
GNOMAD Browser | ENSG00000120616 |
Varsome Browser | EPC1 |
Genomic Variants (DGV) | EPC1 [DGVbeta] |
DECIPHER | EPC1 [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | EPC1 |
| Mutations |
ICGC Data Portal | EPC1 |
TCGA Data Portal | EPC1 |
Broad Tumor Portal | EPC1 |
OASIS Portal | EPC1 [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | EPC1 [overview] [genome browser] [tissue] [distribution] |
Somatic Mutations in Cancer : COSMIC3D | EPC1 |
Mutations and Diseases : HGMD | EPC1 |
intOGen Portal | EPC1 |
LOVD (Leiden Open Variation Database) | Whole genome datasets |
LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
BioMuta | search EPC1 |
DgiDB (Drug Gene Interaction Database) | EPC1 |
DoCM (Curated mutations) | EPC1 (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | EPC1 (select a term) |
intoGen | EPC1 |
Cancer3D | EPC1(select the gene name) |
Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
---|
OMIM | 610999 |
Orphanet | |
DisGeNET | EPC1 |
Medgen | EPC1 |
Genetic Testing Registry | EPC1
|
NextProt | Q9H2F5 [Medical] |
GENETests | EPC1 |
Target Validation | EPC1 |
Huge Navigator |
EPC1 [HugePedia] |
ClinGen | EPC1 |
| Clinical trials, drugs, therapy |
---|
MyCancerGenome | EPC1 |
Protein Interactions : CTD | |
Pharm GKB Gene | PA134981141 |
Pharos | Q9H2F5 |
Clinical trial | EPC1 |
| Miscellaneous |
---|
canSAR (ICR) | EPC1 (select the gene name) |
Harmonizome | EPC1 |
DataMed Index | EPC1 |
| Probes |
---|
| Litterature |
---|
PubMed | 53 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
EVEX | EPC1 |