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EPC2 (enhancer of polycomb homolog 2)

Identity

Alias (NCBI)EPC-LIKE
HGNC (Hugo) EPC2
HGNC Alias symbDKFZP566F2124
HGNC Previous nameenhancer of polycomb homolog 2 (Drosophila)
LocusID (NCBI) 26122
Atlas_Id 50181
Location 2q23.1  [Link to chromosome band 2q23]
Location_base_pair Starts at 148644751 and ends at 148787569 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CD74 (5q32) / EPC2 (2q23.1)CSTA (3q21.1) / EPC2 (2q23.1)EPC2 (2q23.1) / CNKSR3 (6q25.2)
EPC2 (2q23.1) / CSTA (3q21.1)EPC2 (2q23.1) / MBD5 (2q23.1)EPC2 (2q23.1) / PAN3 (13q12.2)
EPC2 (2q23.1) / RANBP3L (5p13.2)EPC2 (2q23.1) / RNF111 (15q22.1)EPC2 (2q23.1) / THRB (3p24.2)
EPC2 (2q23.1) / THSD7B (2q22.1)LOC100506274 (2p25.1) / EPC2 (2q23.1)MBD5 (2q23.1) / EPC2 (2q23.1)
MCPH1 (8p23.1) / EPC2 (2q23.1)MYBBP1A (17p13.2) / EPC2 (2q23.1)PUM1 (1p35.2) / EPC2 (2q23.1)
SNX4 (3q21.2) / EPC2 (2q23.1)TAF7 (5q31.3) / EPC2 (2q23.1)USH2A (1q41) / EPC2 (2q23.1)
EPC2 2q23.1 / MBD5 2q23.1EPC2 2q23.1 / THSD7B 2q22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)EPC2   24543
Cards
Entrez_Gene (NCBI)EPC2    enhancer of polycomb homolog 2
AliasesEPC-LIKE
GeneCards (Weizmann)EPC2
Ensembl hg19 (Hinxton)ENSG00000135999 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135999 [Gene_View]  ENSG00000135999 [Sequence]  chr2:148644751-148787569 [Contig_View]  EPC2 [Vega]
ICGC DataPortalENSG00000135999
TCGA cBioPortalEPC2
AceView (NCBI)EPC2
Genatlas (Paris)EPC2
SOURCE (Princeton)EPC2
Genetics Home Reference (NIH)EPC2
Genomic and cartography
GoldenPath hg38 (UCSC)EPC2  -     chr2:148644751-148787569 +  2q23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EPC2  -     2q23.1   [Description]    (hg19-Feb_2009)
GoldenPathEPC2 - 2q23.1 [CytoView hg19]  EPC2 - 2q23.1 [CytoView hg38]
ImmunoBaseENSG00000135999
Genome Data Viewer NCBIEPC2 [Mapview hg19]  
OMIM611000   
Gene and transcription
Genbank (Entrez)AF286904 AK001433 AK002010 AK125789 AL117558
RefSeq transcript (Entrez)NM_015630
Consensus coding sequences : CCDS (NCBI)EPC2
Gene ExpressionEPC2 [ NCBI-GEO ]   EPC2 [ EBI - ARRAY_EXPRESS ]   EPC2 [ SEEK ]   EPC2 [ MEM ]
Gene Expression Viewer (FireBrowse)EPC2 [ Firebrowse - Broad ]
GenevisibleExpression of EPC2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26122
GTEX Portal (Tissue expression)EPC2
Human Protein AtlasENSG00000135999-EPC2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ52LR7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ52LR7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ52LR7
PhosPhoSitePlusQ52LR7
Domains : Interpro (EBI)Enhancer_polycomb    Enhancer_polycomb-like_N    Enhancer_polycomb_C   
Domain families : Pfam (Sanger)E_Pc_C (PF06752)    EPL1 (PF10513)   
Domain families : Pfam (NCBI)pfam06752    pfam10513   
Conserved Domain (NCBI)EPC2
SuperfamilyQ52LR7
AlphaFold pdb e-kbQ52LR7   
Human Protein Atlas [tissue]ENSG00000135999-EPC2 [tissue]
HPRD13274
Protein Interaction databases
DIP (DOE-UCLA)Q52LR7
IntAct (EBI)Q52LR7
BioGRIDEPC2
STRING (EMBL)EPC2
ZODIACEPC2
Ontologies - Pathways
QuickGOQ52LR7
Ontology : AmiGOhistone acetyltransferase activity  DNA repair  regulation of transcription by RNA polymerase II  histone acetylation  Piccolo NuA4 histone acetyltransferase complex  
Ontology : EGO-EBIhistone acetyltransferase activity  DNA repair  regulation of transcription by RNA polymerase II  histone acetylation  Piccolo NuA4 histone acetyltransferase complex  
NDEx NetworkEPC2
Atlas of Cancer Signalling NetworkEPC2
Wikipedia pathwaysEPC2
Orthology - Evolution
OrthoDB26122
GeneTree (enSembl)ENSG00000135999
Phylogenetic Trees/Animal Genes : TreeFamEPC2
Homologs : HomoloGeneEPC2
Homology/Alignments : Family Browser (UCSC)EPC2
Gene fusions - Rearrangements
Fusion : MitelmanEPC2/MBD5 [2q23.1/2q23.1]  
Fusion : MitelmanEPC2/THSD7B [2q23.1/2q22.1]  
Fusion : QuiverEPC2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEPC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EPC2
dbVarEPC2
ClinVarEPC2
MonarchEPC2
1000_GenomesEPC2 
Exome Variant ServerEPC2
GNOMAD BrowserENSG00000135999
Varsome BrowserEPC2
ACMGEPC2 variants
VarityQ52LR7
Genomic Variants (DGV)EPC2 [DGVbeta]
DECIPHEREPC2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEPC2 
Mutations
ICGC Data PortalEPC2 
TCGA Data PortalEPC2 
Broad Tumor PortalEPC2
OASIS PortalEPC2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEPC2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DEPC2
Mutations and Diseases : HGMDEPC2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaEPC2
DgiDB (Drug Gene Interaction Database)EPC2
DoCM (Curated mutations)EPC2
CIViC (Clinical Interpretations of Variants in Cancer)EPC2
Cancer3DEPC2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611000   
Orphanet
DisGeNETEPC2
MedgenEPC2
Genetic Testing Registry EPC2
NextProtQ52LR7 [Medical]
GENETestsEPC2
Target ValidationEPC2
Huge Navigator EPC2 [HugePedia]
ClinGenEPC2
Clinical trials, drugs, therapy
MyCancerGenomeEPC2
Protein Interactions : CTDEPC2
Pharm GKB GenePA134875170
PharosQ52LR7
Clinical trialEPC2
Miscellaneous
canSAR (ICR)EPC2
HarmonizomeEPC2
DataMed IndexEPC2
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXEPC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:08:16 CEST 2021

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