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EPC2 (enhancer of polycomb homolog 2)

Identity

Alias_namesenhancer of polycomb homolog 2 (Drosophila)
Alias_symbol (synonym)DKFZP566F2124
Other aliasEPC-LIKE
HGNC (Hugo) EPC2
LocusID (NCBI) 26122
Atlas_Id 50181
Location 2q23.1  [Link to chromosome band 2q23]
Location_base_pair Starts at 148644991 and ends at 148787567 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CD74 (5q32) / EPC2 (2q23.1)CSTA (3q21.1) / EPC2 (2q23.1)EPC2 (2q23.1) / CNKSR3 (6q25.2)
EPC2 (2q23.1) / CSTA (3q21.1)EPC2 (2q23.1) / MBD5 (2q23.1)EPC2 (2q23.1) / PAN3 (13q12.2)
EPC2 (2q23.1) / RANBP3L (5p13.2)EPC2 (2q23.1) / RNF111 (15q22.1)EPC2 (2q23.1) / THRB (3p24.2)
EPC2 (2q23.1) / THSD7B (2q22.1)LOC100506274 (2p25.1) / EPC2 (2q23.1)MBD5 (2q23.1) / EPC2 (2q23.1)
MCPH1 (8p23.1) / EPC2 (2q23.1)MYBBP1A (17p13.2) / EPC2 (2q23.1)PUM1 (1p35.2) / EPC2 (2q23.1)
SNX4 (3q21.2) / EPC2 (2q23.1)TAF7 (5q31.3) / EPC2 (2q23.1)USH2A (1q41) / EPC2 (2q23.1)
EPC2 2q23.1 / MBD5 2q23.1EPC2 2q23.1 / THSD7B 2q22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EPC2   24543
Cards
Entrez_Gene (NCBI)EPC2  26122  enhancer of polycomb homolog 2
AliasesEPC-LIKE
GeneCards (Weizmann)EPC2
Ensembl hg19 (Hinxton)ENSG00000135999 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135999 [Gene_View]  chr2:148644991-148787567 [Contig_View]  EPC2 [Vega]
ICGC DataPortalENSG00000135999
TCGA cBioPortalEPC2
AceView (NCBI)EPC2
Genatlas (Paris)EPC2
WikiGenes26122
SOURCE (Princeton)EPC2
Genetics Home Reference (NIH)EPC2
Genomic and cartography
GoldenPath hg38 (UCSC)EPC2  -     chr2:148644991-148787567 +  2q23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EPC2  -     2q23.1   [Description]    (hg19-Feb_2009)
EnsemblEPC2 - 2q23.1 [CytoView hg19]  EPC2 - 2q23.1 [CytoView hg38]
Mapping of homologs : NCBIEPC2 [Mapview hg19]  EPC2 [Mapview hg38]
OMIM611000   
Gene and transcription
Genbank (Entrez)AF286904 AK001433 AK002010 AK125789 AL117558
RefSeq transcript (Entrez)NM_015630
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EPC2
Cluster EST : UnigeneHs.23270 [ NCBI ]
CGAP (NCI)Hs.23270
Alternative Splicing GalleryENSG00000135999
Gene ExpressionEPC2 [ NCBI-GEO ]   EPC2 [ EBI - ARRAY_EXPRESS ]   EPC2 [ SEEK ]   EPC2 [ MEM ]
Gene Expression Viewer (FireBrowse)EPC2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26122
GTEX Portal (Tissue expression)EPC2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ52LR7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ52LR7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ52LR7
Splice isoforms : SwissVarQ52LR7
PhosPhoSitePlusQ52LR7
Domains : Interpro (EBI)Enhancer_polycomb    Enhancer_polycomb-like_N    Enhancer_polycomb_C   
Domain families : Pfam (Sanger)E_Pc_C (PF06752)    EPL1 (PF10513)   
Domain families : Pfam (NCBI)pfam06752    pfam10513   
Conserved Domain (NCBI)EPC2
DMDM Disease mutations26122
Blocks (Seattle)EPC2
SuperfamilyQ52LR7
Human Protein AtlasENSG00000135999
Peptide AtlasQ52LR7
HPRD13274
IPIIPI00141118   IPI00873531   IPI00916837   IPI00916954   IPI00917802   
Protein Interaction databases
DIP (DOE-UCLA)Q52LR7
IntAct (EBI)Q52LR7
FunCoupENSG00000135999
BioGRIDEPC2
STRING (EMBL)EPC2
ZODIACEPC2
Ontologies - Pathways
QuickGOQ52LR7
Ontology : AmiGODNA repair  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  covalent chromatin modification  Piccolo NuA4 histone acetyltransferase complex  
Ontology : EGO-EBIDNA repair  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  covalent chromatin modification  Piccolo NuA4 histone acetyltransferase complex  
NDEx NetworkEPC2
Atlas of Cancer Signalling NetworkEPC2
Wikipedia pathwaysEPC2
Orthology - Evolution
OrthoDB26122
GeneTree (enSembl)ENSG00000135999
Phylogenetic Trees/Animal Genes : TreeFamEPC2
HOVERGENQ52LR7
HOGENOMQ52LR7
Homologs : HomoloGeneEPC2
Homology/Alignments : Family Browser (UCSC)EPC2
Gene fusions - Rearrangements
Fusion : MitelmanEPC2/MBD5 [2q23.1/2q23.1]  
Fusion : MitelmanEPC2/THSD7B [2q23.1/2q22.1]  [t(2;2)(q22;q23)]  
Fusion: TCGAEPC2 2q23.1 MBD5 2q23.1 BRCA
Fusion: TCGAEPC2 2q23.1 THSD7B 2q22.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEPC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EPC2
dbVarEPC2
ClinVarEPC2
1000_GenomesEPC2 
Exome Variant ServerEPC2
ExAC (Exome Aggregation Consortium)EPC2 (select the gene name)
Genetic variants : HAPMAP26122
Genomic Variants (DGV)EPC2 [DGVbeta]
DECIPHEREPC2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEPC2 
Mutations
ICGC Data PortalEPC2 
TCGA Data PortalEPC2 
Broad Tumor PortalEPC2
OASIS PortalEPC2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEPC2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEPC2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EPC2
DgiDB (Drug Gene Interaction Database)EPC2
DoCM (Curated mutations)EPC2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EPC2 (select a term)
intoGenEPC2
Cancer3DEPC2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611000   
Orphanet
MedgenEPC2
Genetic Testing Registry EPC2
NextProtQ52LR7 [Medical]
TSGene26122
GENETestsEPC2
Target ValidationEPC2
Huge Navigator EPC2 [HugePedia]
snp3D : Map Gene to Disease26122
BioCentury BCIQEPC2
ClinGenEPC2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26122
Chemical/Pharm GKB GenePA134875170
Clinical trialEPC2
Miscellaneous
canSAR (ICR)EPC2 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEPC2
EVEXEPC2
GoPubMedEPC2
iHOPEPC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:07:02 CEST 2017

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