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EPHA10 (EPH receptor A10)

Identity

Alias_symbol (synonym)FLJ16103
FLJ33655
Other alias-
HGNC (Hugo) EPHA10
LocusID (NCBI) 284656
Atlas_Id 43243
Location 1p34.3  [Link to chromosome band 1p34]
Location_base_pair Starts at 37715974 and ends at 37765152 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
EPHA10 (1p34.3) / COL8A2 (1p34.3)EPHA10 (1p34.3) / KRT7 (12q13.13)EPHA10 1p34.3 / COL8A2 1p34.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EPHA10   19987
Cards
Entrez_Gene (NCBI)EPHA10  284656  EPH receptor A10
Aliases
GeneCards (Weizmann)EPHA10
Ensembl hg19 (Hinxton)ENSG00000183317 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000183317 [Gene_View]  chr1:37715974-37765152 [Contig_View]  EPHA10 [Vega]
ICGC DataPortalENSG00000183317
TCGA cBioPortalEPHA10
AceView (NCBI)EPHA10
Genatlas (Paris)EPHA10
WikiGenes284656
SOURCE (Princeton)EPHA10
Genetics Home Reference (NIH)EPHA10
Genomic and cartography
GoldenPath hg38 (UCSC)EPHA10  -     chr1:37715974-37765152 -  1p34.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EPHA10  -     1p34.3   [Description]    (hg19-Feb_2009)
EnsemblEPHA10 - 1p34.3 [CytoView hg19]  EPHA10 - 1p34.3 [CytoView hg38]
Mapping of homologs : NCBIEPHA10 [Mapview hg19]  EPHA10 [Mapview hg38]
OMIM611123   
Gene and transcription
Genbank (Entrez)AJ781169 AK090974 AK131215 AK309089 AY726560
RefSeq transcript (Entrez)NM_001004338 NM_001099439 NM_173641
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EPHA10
Cluster EST : UnigeneHs.129435 [ NCBI ]
CGAP (NCI)Hs.129435
Alternative Splicing GalleryENSG00000183317
Gene ExpressionEPHA10 [ NCBI-GEO ]   EPHA10 [ EBI - ARRAY_EXPRESS ]   EPHA10 [ SEEK ]   EPHA10 [ MEM ]
Gene Expression Viewer (FireBrowse)EPHA10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)284656
GTEX Portal (Tissue expression)EPHA10
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5JZY3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5JZY3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5JZY3
Splice isoforms : SwissVarQ5JZY3
Catalytic activity : Enzyme2.7.10.1 [ Enzyme-Expasy ]   2.7.10.12.7.10.1 [ IntEnz-EBI ]   2.7.10.1 [ BRENDA ]   2.7.10.1 [ KEGG ]   
PhosPhoSitePlusQ5JZY3
Domaine pattern : Prosite (Expaxy)EGF_2 (PS01186)    EPH_LBD (PS51550)    FN3 (PS50853)    PROTEIN_KINASE_DOM (PS50011)    RECEPTOR_TYR_KIN_V_1 (PS00790)    RECEPTOR_TYR_KIN_V_2 (PS00791)    SAM_DOMAIN (PS50105)   
Domains : Interpro (EBI)Eph_TM    Ephrin_rcpt_lig-bd_dom    FN3_dom    Galactose-bd-like    Ig-like_fold    Kinase-like_dom    Prot_kinase_dom    SAM    SAM/pointed    Ser-Thr/Tyr_kinase_cat_dom    Tyr-kin_ephrin_A/B_rcpt-like    Tyr_kinase_ephrin_rcpt    Tyr_kinase_rcpt_V_CS   
Domain families : Pfam (Sanger)EphA2_TM (PF14575)    Ephrin_lbd (PF01404)    fn3 (PF00041)    Pkinase_Tyr (PF07714)    SAM_1 (PF00536)   
Domain families : Pfam (NCBI)pfam14575    pfam01404    pfam00041    pfam07714    pfam00536   
Domain families : Smart (EMBL)EPH_lbd (SM00615)  Ephrin_rec_like (SM01411)  FN3 (SM00060)  SAM (SM00454)  
Conserved Domain (NCBI)EPHA10
DMDM Disease mutations284656
Blocks (Seattle)EPHA10
SuperfamilyQ5JZY3
Human Protein AtlasENSG00000183317
Peptide AtlasQ5JZY3
HPRD08163
IPIIPI00166339   IPI00651637   IPI00651751   IPI00555677   IPI00983540   IPI01015345   IPI00984419   IPI00985342   
Protein Interaction databases
DIP (DOE-UCLA)Q5JZY3
IntAct (EBI)Q5JZY3
FunCoupENSG00000183317
BioGRIDEPHA10
STRING (EMBL)EPHA10
ZODIACEPHA10
Ontologies - Pathways
QuickGOQ5JZY3
Ontology : AmiGOephrin receptor activity  protein binding  ATP binding  plasma membrane  integral component of plasma membrane  biological_process  peptidyl-tyrosine phosphorylation  ephrin receptor signaling pathway  extracellular exosome  
Ontology : EGO-EBIephrin receptor activity  protein binding  ATP binding  plasma membrane  integral component of plasma membrane  biological_process  peptidyl-tyrosine phosphorylation  ephrin receptor signaling pathway  extracellular exosome  
NDEx NetworkEPHA10
Atlas of Cancer Signalling NetworkEPHA10
Wikipedia pathwaysEPHA10
Orthology - Evolution
OrthoDB284656
GeneTree (enSembl)ENSG00000183317
Phylogenetic Trees/Animal Genes : TreeFamEPHA10
HOVERGENQ5JZY3
HOGENOMQ5JZY3
Homologs : HomoloGeneEPHA10
Homology/Alignments : Family Browser (UCSC)EPHA10
Gene fusions - Rearrangements
Fusion : MitelmanEPHA10/COL8A2 [1p34.3/1p34.3]  
Fusion: TCGAEPHA10 1p34.3 COL8A2 1p34.3 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEPHA10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EPHA10
dbVarEPHA10
ClinVarEPHA10
1000_GenomesEPHA10 
Exome Variant ServerEPHA10
ExAC (Exome Aggregation Consortium)EPHA10 (select the gene name)
Genetic variants : HAPMAP284656
Genomic Variants (DGV)EPHA10 [DGVbeta]
DECIPHEREPHA10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEPHA10 
Mutations
ICGC Data PortalEPHA10 
TCGA Data PortalEPHA10 
Broad Tumor PortalEPHA10
OASIS PortalEPHA10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEPHA10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEPHA10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EPHA10
DgiDB (Drug Gene Interaction Database)EPHA10
DoCM (Curated mutations)EPHA10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EPHA10 (select a term)
intoGenEPHA10
Cancer3DEPHA10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611123   
Orphanet
MedgenEPHA10
Genetic Testing Registry EPHA10
NextProtQ5JZY3 [Medical]
TSGene284656
GENETestsEPHA10
Target ValidationEPHA10
Huge Navigator EPHA10 [HugePedia]
snp3D : Map Gene to Disease284656
BioCentury BCIQEPHA10
ClinGenEPHA10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD284656
Chemical/Pharm GKB GenePA134938798
Clinical trialEPHA10
Miscellaneous
canSAR (ICR)EPHA10 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEPHA10
EVEXEPHA10
GoPubMedEPHA10
iHOPEPHA10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:52:39 CEST 2017

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