EPHA10 (EPH receptor A10)

2006-10-01  

Identity

HGNC
LOCATION
1p34.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 284656
MIM: 611123
HGNC: 19987
Ensembl: ENSG00000183317

Variants:

dbSNP: 284656
ClinVar: 284656
TCGA: ENSG00000183317
COSMIC: EPHA10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183317ENST00000319637Q5JZY3
ENSG00000183317ENST00000373048Q5JZY3
ENSG00000183317ENST00000427468J3KQG3
ENSG00000183317ENST00000432874H0YER4
ENSG00000183317ENST00000437645H0YD12
ENSG00000183317ENST00000525749H0YEP6
ENSG00000183317ENST00000534097H0YCC9
ENSG00000183317ENST00000540011F5GWI2

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
Axon guidanceREACTOMER-HSA-422475
EPH-Ephrin signalingREACTOMER-HSA-2682334
EPHA-mediated growth cone collapseREACTOMER-HSA-3928663
EPH-ephrin mediated repulsion of cellsREACTOMER-HSA-3928665

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
217376112011A paradigm shift in EPH receptor interaction: biological relevance of EPHB6 interaction with EPHA2 and EPHB2 in breast carcinoma cell lines.15
188197112009Expression profile of Eph receptors and ephrin ligands in healthy human B lymphocytes and chronic lymphocytic leukemia B-cells.11
275666542016EPHA7 and EPHA10 Physically Interact and Differentially Co-localize in Normal Breast and Breast Carcinoma Cell Lines, and the Co-localization Pattern Is Altered in EPHB6-expressing MDA-MB-231 Cells.3
244032712013Expression of Eph receptor A10 is correlated with lymph node metastasis and stage progression in breast cancer patients.0
249246292014Eph receptor A10 has a potential as a target for a prostate cancer therapy.0
249462382014Ephrin receptor A10 is a promising drug target potentially useful for breast cancers including triple negative breast cancers.0
284272232017Isoform expression patterns of EPHA10 protein mediate breast cancer progression by regulating the E-Cadherin and β-catenin complex.0

Citation

Dessen P

EPHA10 (EPH receptor A10)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43243/epha10