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EPHA10 (EPH receptor A10)

Identity

Alias (NCBI)-
HGNC (Hugo) EPHA10
HGNC Alias symbFLJ16103
FLJ33655
LocusID (NCBI) 284656
Atlas_Id 43243
Location 1p34.3  [Link to chromosome band 1p34]
Location_base_pair Starts at 37760273 and ends at 37765152 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EPHA10 (1p34.3) / COL8A2 (1p34.3)EPHA10 (1p34.3) / KRT7 (12q13.13)EPHA10 1p34.3 / COL8A2 1p34.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)EPHA10   19987
Cards
Entrez_Gene (NCBI)EPHA10    EPH receptor A10
Aliases
GeneCards (Weizmann)EPHA10
Ensembl hg19 (Hinxton)ENSG00000183317 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000183317 [Gene_View]  ENSG00000183317 [Sequence]  chr1:37760273-37765152 [Contig_View]  EPHA10 [Vega]
ICGC DataPortalENSG00000183317
TCGA cBioPortalEPHA10
AceView (NCBI)EPHA10
Genatlas (Paris)EPHA10
SOURCE (Princeton)EPHA10
Genetics Home Reference (NIH)EPHA10
Genomic and cartography
GoldenPath hg38 (UCSC)EPHA10  -     chr1:37760273-37765152 -  1p34.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EPHA10  -     1p34.3   [Description]    (hg19-Feb_2009)
GoldenPathEPHA10 - 1p34.3 [CytoView hg19]  EPHA10 - 1p34.3 [CytoView hg38]
ImmunoBaseENSG00000183317
Genome Data Viewer NCBIEPHA10 [Mapview hg19]  
OMIM611123   
Gene and transcription
Genbank (Entrez)AJ781169 AK090974 AK131215 AK309089 AY726560
RefSeq transcript (Entrez)NM_001004338 NM_001099439 NM_173641
Consensus coding sequences : CCDS (NCBI)EPHA10
Gene ExpressionEPHA10 [ NCBI-GEO ]   EPHA10 [ EBI - ARRAY_EXPRESS ]   EPHA10 [ SEEK ]   EPHA10 [ MEM ]
Gene Expression Viewer (FireBrowse)EPHA10 [ Firebrowse - Broad ]
GenevisibleExpression of EPHA10 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)284656
GTEX Portal (Tissue expression)EPHA10
Human Protein AtlasENSG00000183317-EPHA10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5JZY3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5JZY3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5JZY3
Catalytic activity : Enzyme2.7.10.1 [ Enzyme-Expasy ]   2.7.10.12.7.10.1 [ IntEnz-EBI ]   2.7.10.1 [ BRENDA ]   2.7.10.1 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ5JZY3
Domaine pattern : Prosite (Expaxy)EGF_2 (PS01186)    EPH_LBD (PS51550)    FN3 (PS50853)    PROTEIN_KINASE_DOM (PS50011)    RECEPTOR_TYR_KIN_V_1 (PS00790)    RECEPTOR_TYR_KIN_V_2 (PS00791)    SAM_DOMAIN (PS50105)   
Domains : Interpro (EBI)Eph_TM    Ephrin_rcpt_lig-bd_dom    FN3_dom    FN3_sf    Galactose-bd-like_sf    Ig-like_fold    Kinase-like_dom_sf    Prot_kinase_dom    SAM    SAM/pointed_sf    Ser-Thr/Tyr_kinase_cat_dom    Tyr-kin_ephrin_A/B_rcpt-like    Tyr_kinase_ephrin_rcpt    Tyr_kinase_rcpt_V_CS   
Domain families : Pfam (Sanger)EphA2_TM (PF14575)    Ephrin_lbd (PF01404)    fn3 (PF00041)    PK_Tyr_Ser-Thr (PF07714)    SAM_1 (PF00536)   
Domain families : Pfam (NCBI)pfam14575    pfam01404    pfam00041    pfam07714    pfam00536   
Domain families : Smart (EMBL)EPH_lbd (SM00615)  Ephrin_rec_like (SM01411)  FN3 (SM00060)  SAM (SM00454)  
Conserved Domain (NCBI)EPHA10
SuperfamilyQ5JZY3
AlphaFold pdb e-kbQ5JZY3   
Human Protein Atlas [tissue]ENSG00000183317-EPHA10 [tissue]
HPRD08163
Protein Interaction databases
DIP (DOE-UCLA)Q5JZY3
IntAct (EBI)Q5JZY3
BioGRIDEPHA10
STRING (EMBL)EPHA10
ZODIACEPHA10
Ontologies - Pathways
QuickGOQ5JZY3
Ontology : AmiGOtransmembrane receptor protein tyrosine kinase activity  transmembrane-ephrin receptor activity  protein binding  ATP binding  extracellular region  plasma membrane  integral component of plasma membrane  transmembrane receptor protein tyrosine kinase signaling pathway  multicellular organism development  axon guidance  biological_process  peptidyl-tyrosine phosphorylation  positive regulation of kinase activity  neuron projection  receptor complex  ephrin receptor signaling pathway  
Ontology : EGO-EBItransmembrane receptor protein tyrosine kinase activity  transmembrane-ephrin receptor activity  protein binding  ATP binding  extracellular region  plasma membrane  integral component of plasma membrane  transmembrane receptor protein tyrosine kinase signaling pathway  multicellular organism development  axon guidance  biological_process  peptidyl-tyrosine phosphorylation  positive regulation of kinase activity  neuron projection  receptor complex  ephrin receptor signaling pathway  
NDEx NetworkEPHA10
Atlas of Cancer Signalling NetworkEPHA10
Wikipedia pathwaysEPHA10
Orthology - Evolution
OrthoDB284656
GeneTree (enSembl)ENSG00000183317
Phylogenetic Trees/Animal Genes : TreeFamEPHA10
Homologs : HomoloGeneEPHA10
Homology/Alignments : Family Browser (UCSC)EPHA10
Gene fusions - Rearrangements
Fusion : MitelmanEPHA10/COL8A2 [1p34.3/1p34.3]  
Fusion : QuiverEPHA10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEPHA10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EPHA10
dbVarEPHA10
ClinVarEPHA10
MonarchEPHA10
1000_GenomesEPHA10 
Exome Variant ServerEPHA10
GNOMAD BrowserENSG00000183317
Varsome BrowserEPHA10
ACMGEPHA10 variants
VarityQ5JZY3
Genomic Variants (DGV)EPHA10 [DGVbeta]
DECIPHEREPHA10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEPHA10 
Mutations
ICGC Data PortalEPHA10 
TCGA Data PortalEPHA10 
Broad Tumor PortalEPHA10
OASIS PortalEPHA10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEPHA10  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DEPHA10
Mutations and Diseases : HGMDEPHA10
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaEPHA10
DgiDB (Drug Gene Interaction Database)EPHA10
DoCM (Curated mutations)EPHA10
CIViC (Clinical Interpretations of Variants in Cancer)EPHA10
Cancer3DEPHA10
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611123   
Orphanet
DisGeNETEPHA10
MedgenEPHA10
Genetic Testing Registry EPHA10
NextProtQ5JZY3 [Medical]
GENETestsEPHA10
Target ValidationEPHA10
Huge Navigator EPHA10 [HugePedia]
ClinGenEPHA10
Clinical trials, drugs, therapy
MyCancerGenomeEPHA10
Protein Interactions : CTDEPHA10
Pharm GKB GenePA134938798
PharosQ5JZY3
Clinical trialEPHA10
Miscellaneous
canSAR (ICR)EPHA10
HarmonizomeEPHA10
DataMed IndexEPHA10
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXEPHA10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:08:17 CEST 2021

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