EPN2 (epsin 2)

2016-01-01  

Identity

HGNC
EPN2
LOCATION
17p11.2
LOCUSID
22905
ALIAS
EHB21
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 22905
MIM: 607263
HGNC: 18639
Ensembl: ENSG00000072134

Variants:

dbSNP: 22905
ClinVar: 22905
TCGA: ENSG00000072134
COSMIC: EPN2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000072134ENST00000314728O95208
ENSG00000072134ENST00000347697O95208
ENSG00000072134ENST00000395618O95208
ENSG00000072134ENST00000395620O95208
ENSG00000072134ENST00000395626E9PBC1
ENSG00000072134ENST00000395628F6PQP6
ENSG00000072134ENST00000494192I3L356
ENSG00000072134ENST00000571254I3L2B2
ENSG00000072134ENST00000575595I3L2H1
ENSG00000072134ENST00000577195J3KSA6
ENSG00000072134ENST00000577692J3QLN2
ENSG00000072134ENST00000580579J3QQJ8
ENSG00000072134ENST00000581024J3KTF6
ENSG00000072134ENST00000582015J3KSF8
ENSG00000072134ENST00000583197J3QKL8
ENSG00000072134ENST00000584150J3KSR0
ENSG00000072134ENST00000584633J3KSC7

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Clathrin-mediated endocytosisREACTOMER-HSA-8856828
Cargo recognition for clathrin-mediated endocytosisREACTOMER-HSA-8856825

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
258710092015Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development.12
287172252017A mammalian mirtron miR-1224 promotes tube-formation of human primary endothelial cells by targeting anti-angiogenic factor epsin2.1

Citation

Dessen P

EPN2 (epsin 2)

Atlas Genet Cytogenet Oncol Haematol. 2016-01-01

Online version: http://atlasgeneticsoncology.org/gene/55609/epn2