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EPPIN (epididymal peptidase inhibitor)

Identity

Alias_namesSPINLW1
serine protease inhibitor-like, with Kunitz and WAP domains 1 (eppin)
serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin)
Alias_symbol (synonym)EPPIN1
EPPIN2
EPPIN3
dJ461P17.2
WAP7
WFDC7
CT71
Other aliasCT72
HGNC (Hugo) EPPIN
LocusID (NCBI) 57119
Atlas_Id 52857
Location 20q13.12  [Link to chromosome band 20q13]
Location_base_pair Starts at 45541845 and ends at 45547426 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EPPIN   15932
Cards
Entrez_Gene (NCBI)EPPIN  57119  epididymal peptidase inhibitor
AliasesCT71; CT72; SPINLW1; WAP7; 
WFDC7; dJ461P17.2
GeneCards (Weizmann)EPPIN
Ensembl hg19 (Hinxton)ENSG00000101448 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101448 [Gene_View]  chr20:45541845-45547426 [Contig_View]  EPPIN [Vega]
ICGC DataPortalENSG00000101448
TCGA cBioPortalEPPIN
AceView (NCBI)EPPIN
Genatlas (Paris)EPPIN
WikiGenes57119
SOURCE (Princeton)EPPIN
Genetics Home Reference (NIH)EPPIN
Genomic and cartography
GoldenPath hg38 (UCSC)EPPIN  -     chr20:45541845-45547426 -  20q13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EPPIN  -     20q13.12   [Description]    (hg19-Feb_2009)
EnsemblEPPIN - 20q13.12 [CytoView hg19]  EPPIN - 20q13.12 [CytoView hg38]
Mapping of homologs : NCBIEPPIN [Mapview hg19]  EPPIN [Mapview hg38]
OMIM609031   
Gene and transcription
Genbank (Entrez)AF286368 AF286369 AF286370 AK126022 AK311906
RefSeq transcript (Entrez)NM_001302861 NM_020398 NM_181502
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EPPIN
Cluster EST : UnigeneHs.121084 [ NCBI ]
CGAP (NCI)Hs.121084
Alternative Splicing GalleryENSG00000101448
Gene ExpressionEPPIN [ NCBI-GEO ]   EPPIN [ EBI - ARRAY_EXPRESS ]   EPPIN [ SEEK ]   EPPIN [ MEM ]
Gene Expression Viewer (FireBrowse)EPPIN [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57119
GTEX Portal (Tissue expression)EPPIN
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95925   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95925  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95925
Splice isoforms : SwissVarO95925
PhosPhoSitePlusO95925
Domaine pattern : Prosite (Expaxy)BPTI_KUNITZ_1 (PS00280)    BPTI_KUNITZ_2 (PS50279)    WAP (PS51390)   
Domains : Interpro (EBI)Kunitz_BPTI    Prtase_inh_Kunz-CS    WAP_dom   
Domain families : Pfam (Sanger)Kunitz_BPTI (PF00014)    WAP (PF00095)   
Domain families : Pfam (NCBI)pfam00014    pfam00095   
Domain families : Smart (EMBL)KU (SM00131)  WAP (SM00217)  
Conserved Domain (NCBI)EPPIN
DMDM Disease mutations57119
Blocks (Seattle)EPPIN
SuperfamilyO95925
Human Protein AtlasENSG00000101448
Peptide AtlasO95925
HPRD10615
IPIIPI00001372   IPI00220471   IPI00902510   IPI01018708   IPI00793266   
Protein Interaction databases
DIP (DOE-UCLA)O95925
IntAct (EBI)O95925
FunCoupENSG00000101448
BioGRIDEPPIN
STRING (EMBL)EPPIN
ZODIACEPPIN
Ontologies - Pathways
QuickGOO95925
Ontology : AmiGOserine-type endopeptidase inhibitor activity  protein binding  extracellular space  cell surface  negative regulation of peptidase activity  negative regulation of endopeptidase activity  antimicrobial humoral response  defense response to bacterium  protein complex  protein oligomerization  negative regulation of calcium ion import  sperm plasma membrane  negative regulation of flagellated sperm motility  
Ontology : EGO-EBIserine-type endopeptidase inhibitor activity  protein binding  extracellular space  cell surface  negative regulation of peptidase activity  negative regulation of endopeptidase activity  antimicrobial humoral response  defense response to bacterium  protein complex  protein oligomerization  negative regulation of calcium ion import  sperm plasma membrane  negative regulation of flagellated sperm motility  
NDEx NetworkEPPIN
Atlas of Cancer Signalling NetworkEPPIN
Wikipedia pathwaysEPPIN
Orthology - Evolution
OrthoDB57119
GeneTree (enSembl)ENSG00000101448
Phylogenetic Trees/Animal Genes : TreeFamEPPIN
HOVERGENO95925
HOGENOMO95925
Homologs : HomoloGeneEPPIN
Homology/Alignments : Family Browser (UCSC)EPPIN
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEPPIN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EPPIN
dbVarEPPIN
ClinVarEPPIN
1000_GenomesEPPIN 
Exome Variant ServerEPPIN
ExAC (Exome Aggregation Consortium)EPPIN (select the gene name)
Genetic variants : HAPMAP57119
Genomic Variants (DGV)EPPIN [DGVbeta]
DECIPHEREPPIN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEPPIN 
Mutations
ICGC Data PortalEPPIN 
TCGA Data PortalEPPIN 
Broad Tumor PortalEPPIN
OASIS PortalEPPIN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEPPIN  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEPPIN
BioMutasearch EPPIN
DgiDB (Drug Gene Interaction Database)EPPIN
DoCM (Curated mutations)EPPIN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EPPIN (select a term)
intoGenEPPIN
Cancer3DEPPIN(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609031   
Orphanet
MedgenEPPIN
Genetic Testing Registry EPPIN
NextProtO95925 [Medical]
TSGene57119
GENETestsEPPIN
Target ValidationEPPIN
Huge Navigator EPPIN [HugePedia]
snp3D : Map Gene to Disease57119
BioCentury BCIQEPPIN
ClinGenEPPIN
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57119
Chemical/Pharm GKB GenePA38054
Clinical trialEPPIN
Miscellaneous
canSAR (ICR)EPPIN (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEPPIN
EVEXEPPIN
GoPubMedEPPIN
iHOPEPPIN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:07:08 CEST 2017

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