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ERF (ETS2 repressor factor)

Identity

Alias_namesEts2 repressor factor
Alias_symbol (synonym)PE-2
PE2
Other aliasCRS4
HGNC (Hugo) ERF
LocusID (NCBI) 2077
Atlas_Id 40485
Location 19q13.2  [Link to chromosome band 19q13]
Location_base_pair Starts at 42751713 and ends at 42758787 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ERF (19q13.2) / GSK3A (19q13.2)ERF (19q13.2) / NOC4L (12q24.33)PTPN1 (20q13.13) / ERF (19q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ERF   3444
Cards
Entrez_Gene (NCBI)ERF  2077  ETS2 repressor factor
AliasesCRS4; PE-2; PE2
GeneCards (Weizmann)ERF
Ensembl hg19 (Hinxton)ENSG00000105722 [Gene_View]  chr19:42751713-42758787 [Contig_View]  ERF [Vega]
Ensembl hg38 (Hinxton)ENSG00000105722 [Gene_View]  chr19:42751713-42758787 [Contig_View]  ERF [Vega]
ICGC DataPortalENSG00000105722
TCGA cBioPortalERF
AceView (NCBI)ERF
Genatlas (Paris)ERF
WikiGenes2077
SOURCE (Princeton)ERF
Genetics Home Reference (NIH)ERF
Genomic and cartography
GoldenPath hg19 (UCSC)ERF  -     chr19:42751713-42758787 -  19q13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ERF  -     19q13.2   [Description]    (hg38-Dec_2013)
EnsemblERF - 19q13.2 [CytoView hg19]  ERF - 19q13.2 [CytoView hg38]
Mapping of homologs : NCBIERF [Mapview hg19]  ERF [Mapview hg38]
OMIM600775   611888   
Gene and transcription
Genbank (Entrez)AA961500 AB209271 AK297666 AK300627 AK314278
RefSeq transcript (Entrez)NM_001301035 NM_001308402 NM_001312656 NM_006494
RefSeq genomic (Entrez)NC_000019 NC_018930 NG_042802 NT_011109 NW_004929415
Consensus coding sequences : CCDS (NCBI)ERF
Cluster EST : UnigeneHs.655969 [ NCBI ]
CGAP (NCI)Hs.655969
Alternative Splicing GalleryENSG00000105722
Gene ExpressionERF [ NCBI-GEO ]   ERF [ EBI - ARRAY_EXPRESS ]   ERF [ SEEK ]   ERF [ MEM ]
Gene Expression Viewer (FireBrowse)ERF [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2077
GTEX Portal (Tissue expression)ERF
Protein : pattern, domain, 3D structure
UniProt/SwissProtP50548   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP50548  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP50548
Splice isoforms : SwissVarP50548
PhosPhoSitePlusP50548
Domaine pattern : Prosite (Expaxy)ETS_DOMAIN_1 (PS00345)    ETS_DOMAIN_2 (PS00346)    ETS_DOMAIN_3 (PS50061)   
Domains : Interpro (EBI)ERF    Ets_dom    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)Ets (PF00178)   
Domain families : Pfam (NCBI)pfam00178   
Domain families : Smart (EMBL)ETS (SM00413)  
Conserved Domain (NCBI)ERF
DMDM Disease mutations2077
Blocks (Seattle)ERF
SuperfamilyP50548
Human Protein AtlasENSG00000105722
Peptide AtlasP50548
HPRD09942
IPIIPI00032936   IPI01015514   
Protein Interaction databases
DIP (DOE-UCLA)P50548
IntAct (EBI)P50548
FunCoupENSG00000105722
BioGRIDERF
STRING (EMBL)ERF
ZODIACERF
Ontologies - Pathways
QuickGOP50548
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II transcription factor activity, sequence-specific DNA binding  transcription corepressor activity  nucleus  nucleus  nucleoplasm  Golgi apparatus  cytosol  transcription, DNA-templated  cell cycle  cell differentiation  sequence-specific DNA binding  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II transcription factor activity, sequence-specific DNA binding  transcription corepressor activity  nucleus  nucleus  nucleoplasm  Golgi apparatus  cytosol  transcription, DNA-templated  cell cycle  cell differentiation  sequence-specific DNA binding  
NDEx NetworkERF
Atlas of Cancer Signalling NetworkERF
Wikipedia pathwaysERF
Orthology - Evolution
OrthoDB2077
GeneTree (enSembl)ENSG00000105722
Phylogenetic Trees/Animal Genes : TreeFamERF
HOVERGENP50548
HOGENOMP50548
Homologs : HomoloGeneERF
Homology/Alignments : Family Browser (UCSC)ERF
Gene fusions - Rearrangements
Fusion : MitelmanERF/GSK3A [19q13.2/19q13.2]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerERF [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ERF
dbVarERF
ClinVarERF
1000_GenomesERF 
Exome Variant ServerERF
ExAC (Exome Aggregation Consortium)ERF (select the gene name)
Genetic variants : HAPMAP2077
Genomic Variants (DGV)ERF [DGVbeta]
DECIPHER (Syndromes)19:42751713-42758787  ENSG00000105722
CONAN: Copy Number AnalysisERF 
Mutations
ICGC Data PortalERF 
TCGA Data PortalERF 
Broad Tumor PortalERF
OASIS PortalERF [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICERF  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDERF
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ERF
DgiDB (Drug Gene Interaction Database)ERF
DoCM (Curated mutations)ERF (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ERF (select a term)
intoGenERF
Cancer3DERF(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600775    611888   
Orphanet244    521    2918    10367   
MedgenERF
Genetic Testing Registry ERF
NextProtP50548 [Medical]
TSGene2077
GENETestsERF
Huge Navigator ERF [HugePedia]
snp3D : Map Gene to Disease2077
BioCentury BCIQERF
ClinGenERF
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2077
Chemical/Pharm GKB GenePA27857
Clinical trialERF
Miscellaneous
canSAR (ICR)ERF (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineERF
EVEXERF
GoPubMedERF
iHOPERF
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:00:18 CEST 2017

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