ERFE (erythroferrone)

2001-01-01  

Identity

HGNC
ERFE
LOCATION
2q37.3
LOCUSID
151176
ALIAS
C1QTNF15,CTRP15,FAM132B

Other Information

Locus ID:

NCBI: 151176
MIM: 615099
HGNC: 26727
Ensembl: ENSG00000178752

Variants:

dbSNP: 151176
ClinVar: 151176
TCGA: ENSG00000178752
COSMIC: ERFE

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000178752ENST00000344233H0Y2X4
ENSG00000178752ENST00000357303H7BY19
ENSG00000178752ENST00000546354Q4G0M1

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
223517732012Myonectin (CTRP15), a novel myokine that links skeletal muscle to systemic lipid homeostasis.87
271460132016Regulation of Hepcidin by Erythropoiesis: The Story So Far.14
269785242016Associations among Erythroferrone and Biomarkers of Erythropoiesis and Iron Metabolism, and Treatment with Long-Term Erythropoiesis-Stimulating Agents in Patients on Hemodialysis.7
275400142016Increased levels of ERFE-encoding FAM132B in patients with congenital dyserythropoietic anemia type II.4
294194242018Levels of the erythropoietin-responsive hormone erythroferrone in mice and humans with chronic kidney disease.4
303032692019Circulating C1q/TNF-related protein isoform 15 is a marker for the presence of metabolic syndrome.2
286667152018[The role of erythroferrone in iron metabolism: From experimental results to pathogenesis].1
314000172019The BMP-SMAD pathway mediates the impaired hepatic iron metabolism associated with the ERFE-A260S variant.1
318344562020Erythroferrone, the new iron regulator: evaluation of its levels in Egyptian patients with beta thalassemia.0

Citation

Dessen P

ERFE (erythroferrone)

Atlas Genet Cytogenet Oncol Haematol. 2001-01-01

Online version: http://atlasgeneticsoncology.org/gene/78347/erfe