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ERLIN1 (ER lipid raft associated 1)

Identity

Alias_namesC10orf69
SPFH1
chromosome 10 open reading frame 69
SPFH domain family, member 1
Alias_symbol (synonym)KE04
Erlin-1
SPG62
Other aliasKEO4
HGNC (Hugo) ERLIN1
LocusID (NCBI) 10613
Atlas_Id 62895
Location 10q24.31  [Link to chromosome band 10q24]
Location_base_pair Starts at 100150090 and ends at 100186057 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ERLIN1 (10q24.31) / ERLIN1 (10q24.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ERLIN1   16947
Cards
Entrez_Gene (NCBI)ERLIN1  10613  ER lipid raft associated 1
AliasesC10orf69; Erlin-1; KE04; KEO4; 
SPFH1; SPG62
GeneCards (Weizmann)ERLIN1
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr10:100150090-100186057 [Contig_View]  ERLIN1 [Vega]
TCGA cBioPortalERLIN1
AceView (NCBI)ERLIN1
Genatlas (Paris)ERLIN1
WikiGenes10613
SOURCE (Princeton)ERLIN1
Genetics Home Reference (NIH)ERLIN1
Genomic and cartography
GoldenPath hg38 (UCSC)ERLIN1  -     chr10:100150090-100186057 -  10q24.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ERLIN1  -     10q24.31   [Description]    (hg19-Feb_2009)
EnsemblERLIN1 - 10q24.31 [CytoView hg19]  ERLIN1 - 10q24.31 [CytoView hg38]
Mapping of homologs : NCBIERLIN1 [Mapview hg19]  ERLIN1 [Mapview hg38]
OMIM611604   615681   
Gene and transcription
Genbank (Entrez)AF064093 AK056574 AK127017 AK222480 AK298427
RefSeq transcript (Entrez)NM_001100626 NM_001347856 NM_001347857 NM_001347858 NM_001347859 NM_001347860 NM_001347861 NM_006459
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ERLIN1
Cluster EST : UnigeneHs.150087 [ NCBI ]
CGAP (NCI)Hs.150087
Gene ExpressionERLIN1 [ NCBI-GEO ]   ERLIN1 [ EBI - ARRAY_EXPRESS ]   ERLIN1 [ SEEK ]   ERLIN1 [ MEM ]
Gene Expression Viewer (FireBrowse)ERLIN1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10613
GTEX Portal (Tissue expression)ERLIN1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75477   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75477  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75477
Splice isoforms : SwissVarO75477
PhosPhoSitePlusO75477
Domains : Interpro (EBI)Band_7    Erlin1/2   
Domain families : Pfam (Sanger)Band_7 (PF01145)   
Domain families : Pfam (NCBI)pfam01145   
Domain families : Smart (EMBL)PHB (SM00244)  
Conserved Domain (NCBI)ERLIN1
DMDM Disease mutations10613
Blocks (Seattle)ERLIN1
SuperfamilyO75477
Peptide AtlasO75477
HPRD08502
IPIIPI00936931   IPI00007940   IPI00879747   
Protein Interaction databases
DIP (DOE-UCLA)O75477
IntAct (EBI)O75477
BioGRIDERLIN1
STRING (EMBL)ERLIN1
ZODIACERLIN1
Ontologies - Pathways
QuickGOO75477
Ontology : AmiGOprotein binding  endoplasmic reticulum  endoplasmic reticulum membrane  endoplasmic reticulum membrane  cholesterol metabolic process  cholesterol binding  integral component of membrane  ubiquitin-dependent ERAD pathway  ubiquitin protein ligase binding  SREBP signaling pathway  protein complex  negative regulation of cholesterol biosynthetic process  negative regulation of fatty acid biosynthetic process  transmembrane transport  
Ontology : EGO-EBIprotein binding  endoplasmic reticulum  endoplasmic reticulum membrane  endoplasmic reticulum membrane  cholesterol metabolic process  cholesterol binding  integral component of membrane  ubiquitin-dependent ERAD pathway  ubiquitin protein ligase binding  SREBP signaling pathway  protein complex  negative regulation of cholesterol biosynthetic process  negative regulation of fatty acid biosynthetic process  transmembrane transport  
NDEx NetworkERLIN1
Atlas of Cancer Signalling NetworkERLIN1
Wikipedia pathwaysERLIN1
Orthology - Evolution
OrthoDB10613
Phylogenetic Trees/Animal Genes : TreeFamERLIN1
HOVERGENO75477
HOGENOMO75477
Homologs : HomoloGeneERLIN1
Homology/Alignments : Family Browser (UCSC)ERLIN1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerERLIN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ERLIN1
dbVarERLIN1
ClinVarERLIN1
1000_GenomesERLIN1 
Exome Variant ServerERLIN1
ExAC (Exome Aggregation Consortium)ERLIN1 (select the gene name)
Genetic variants : HAPMAP10613
Genomic Variants (DGV)ERLIN1 [DGVbeta]
DECIPHERERLIN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisERLIN1 
Mutations
ICGC Data PortalERLIN1 
TCGA Data PortalERLIN1 
Broad Tumor PortalERLIN1
OASIS PortalERLIN1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDERLIN1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ERLIN1
DgiDB (Drug Gene Interaction Database)ERLIN1
DoCM (Curated mutations)ERLIN1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ERLIN1 (select a term)
intoGenERLIN1
Cancer3DERLIN1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611604    615681   
Orphanet22829   
MedgenERLIN1
Genetic Testing Registry ERLIN1
NextProtO75477 [Medical]
TSGene10613
GENETestsERLIN1
Target ValidationERLIN1
Huge Navigator ERLIN1 [HugePedia]
snp3D : Map Gene to Disease10613
BioCentury BCIQERLIN1
ClinGenERLIN1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10613
Chemical/Pharm GKB GenePA162385299
Clinical trialERLIN1
Miscellaneous
canSAR (ICR)ERLIN1 (select the gene name)
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineERLIN1
EVEXERLIN1
GoPubMedERLIN1
iHOPERLIN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:07:14 CEST 2017

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