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ERO1A (endoplasmic reticulum oxidoreductase alpha)

Identity

Alias_namesERO1L
ERO1 (S. cerevisiae)-like
ERO1-like (S. cerevisiae)
Alias_symbol (synonym)ERO1-alpha
Ero1alpha
Other aliasERO1-L
ERO1-L-alpha
ERO1LA
HGNC (Hugo) ERO1A
LocusID (NCBI) 30001
Atlas_Id 45895
Location 14q22.1  [Link to chromosome band 14q22]
Location_base_pair Starts at 53106633 and ends at 53162649 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ERO1A (14q22.1) / ERO1A (14q22.1)ERO1A (14q22.1) / FERMT2 (14q22.1)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)ERO1A   13280
Cards
Entrez_Gene (NCBI)ERO1A  30001  endoplasmic reticulum oxidoreductase alpha
AliasesERO1-L; ERO1-L-alpha; ERO1-alpha; ERO1L; 
ERO1LA; Ero1alpha
GeneCards (Weizmann)ERO1A
Ensembl hg19 (Hinxton)ENSG00000197930 [Gene_View]  chr14:53106633-53162649 [Contig_View]  ERO1A [Vega]
Ensembl hg38 (Hinxton)ENSG00000197930 [Gene_View]  chr14:53106633-53162649 [Contig_View]  ERO1A [Vega]
ICGC DataPortalENSG00000197930
TCGA cBioPortalERO1A
AceView (NCBI)ERO1A
Genatlas (Paris)ERO1A
WikiGenes30001
SOURCE (Princeton)ERO1A
Genetics Home Reference (NIH)ERO1A
Genomic and cartography
GoldenPath hg19 (UCSC)ERO1A  -     chr14:53106633-53162649 -  14q22.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ERO1A  -     14q22.1   [Description]    (hg38-Dec_2013)
EnsemblERO1A - 14q22.1 [CytoView hg19]  ERO1A - 14q22.1 [CytoView hg38]
Mapping of homologs : NCBIERO1A [Mapview hg19]  ERO1A [Mapview hg38]
OMIM615435   
Gene and transcription
Genbank (Entrez)AF081886 AF123887 AK024224 AK292839 AY358463
RefSeq transcript (Entrez)NM_014584
RefSeq genomic (Entrez)NC_000014 NC_018925 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)ERO1A
Cluster EST : UnigeneHs.592304 [ NCBI ]
CGAP (NCI)Hs.592304
Alternative Splicing GalleryENSG00000197930
Gene ExpressionERO1A [ NCBI-GEO ]   ERO1A [ EBI - ARRAY_EXPRESS ]   ERO1A [ SEEK ]   ERO1A [ MEM ]
Gene Expression Viewer (FireBrowse)ERO1A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)30001
GTEX Portal (Tissue expression)ERO1A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96HE7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96HE7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96HE7
Splice isoforms : SwissVarQ96HE7
Catalytic activity : Enzyme1.8.4.- [ Enzyme-Expasy ]   1.8.4.-1.8.4.- [ IntEnz-EBI ]   1.8.4.- [ BRENDA ]   1.8.4.- [ KEGG ]   
PhosPhoSitePlusQ96HE7
Domains : Interpro (EBI)Ero1   
Domain families : Pfam (Sanger)ERO1 (PF04137)   
Domain families : Pfam (NCBI)pfam04137   
Conserved Domain (NCBI)ERO1A
DMDM Disease mutations30001
Blocks (Seattle)ERO1A
PDB (SRS)3AHQ    3AHR   
PDB (PDBSum)3AHQ    3AHR   
PDB (IMB)3AHQ    3AHR   
PDB (RSDB)3AHQ    3AHR   
Structural Biology KnowledgeBase3AHQ    3AHR   
SCOP (Structural Classification of Proteins)3AHQ    3AHR   
CATH (Classification of proteins structures)3AHQ    3AHR   
SuperfamilyQ96HE7
Human Protein AtlasENSG00000197930
Peptide AtlasQ96HE7
HPRD13278
IPIIPI00386755   IPI01026033   IPI01025839   IPI01026412   IPI01025642   
Protein Interaction databases
DIP (DOE-UCLA)Q96HE7
IntAct (EBI)Q96HE7
FunCoupENSG00000197930
BioGRIDERO1A
STRING (EMBL)ERO1A
ZODIACERO1A
Ontologies - Pathways
QuickGOQ96HE7
Ontology : AmiGOresponse to reactive oxygen species  protein disulfide isomerase activity  protein binding  endoplasmic reticulum  endoplasmic reticulum lumen  endoplasmic reticulum membrane  protein folding  cellular protein modification process  response to temperature stimulus  organ senescence  protein disulfide oxidoreductase activity  disulfide oxidoreductase activity  membrane  oxidoreductase activity  oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor  4-hydroxyproline metabolic process  protein maturation by protein folding  extracellular matrix organization  dendrite  endoplasmic reticulum unfolded protein response  response to endoplasmic reticulum stress  intracellular membrane-bounded organelle  cell redox homeostasis  brown fat cell differentiation  chaperone mediated protein folding requiring cofactor  release of sequestered calcium ion into cytosol  oxidation-reduction process  intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress  cellular response to hypoxia  
Ontology : EGO-EBIresponse to reactive oxygen species  protein disulfide isomerase activity  protein binding  endoplasmic reticulum  endoplasmic reticulum lumen  endoplasmic reticulum membrane  protein folding  cellular protein modification process  response to temperature stimulus  organ senescence  protein disulfide oxidoreductase activity  disulfide oxidoreductase activity  membrane  oxidoreductase activity  oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor  4-hydroxyproline metabolic process  protein maturation by protein folding  extracellular matrix organization  dendrite  endoplasmic reticulum unfolded protein response  response to endoplasmic reticulum stress  intracellular membrane-bounded organelle  cell redox homeostasis  brown fat cell differentiation  chaperone mediated protein folding requiring cofactor  release of sequestered calcium ion into cytosol  oxidation-reduction process  intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress  cellular response to hypoxia  
NDEx NetworkERO1A
Atlas of Cancer Signalling NetworkERO1A
Wikipedia pathwaysERO1A
Orthology - Evolution
OrthoDB30001
GeneTree (enSembl)ENSG00000197930
Phylogenetic Trees/Animal Genes : TreeFamERO1A
HOVERGENQ96HE7
HOGENOMQ96HE7
Homologs : HomoloGeneERO1A
Homology/Alignments : Family Browser (UCSC)ERO1A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerERO1A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ERO1A
dbVarERO1A
ClinVarERO1A
1000_GenomesERO1A 
Exome Variant ServerERO1A
ExAC (Exome Aggregation Consortium)ERO1A (select the gene name)
Genetic variants : HAPMAP30001
Genomic Variants (DGV)ERO1A [DGVbeta]
DECIPHER (Syndromes)14:53106633-53162649  ENSG00000197930
CONAN: Copy Number AnalysisERO1A 
Mutations
ICGC Data PortalERO1A 
TCGA Data PortalERO1A 
Broad Tumor PortalERO1A
OASIS PortalERO1A [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDERO1A
BioMutasearch ERO1A
DgiDB (Drug Gene Interaction Database)ERO1A
DoCM (Curated mutations)ERO1A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ERO1A (select a term)
intoGenERO1A
Cancer3DERO1A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615435   
Orphanet
MedgenERO1A
Genetic Testing Registry ERO1A
NextProtQ96HE7 [Medical]
TSGene30001
GENETestsERO1A
Huge Navigator ERO1A [HugePedia]
snp3D : Map Gene to Disease30001
BioCentury BCIQERO1A
ClinGenERO1A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD30001
Chemical/Pharm GKB GenePA27862
Clinical trialERO1A
Miscellaneous
canSAR (ICR)ERO1A (select the gene name)
Probes
Litterature
PubMed61 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineERO1A
EVEXERO1A
GoPubMedERO1A
iHOPERO1A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:04:58 CET 2017

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