ERP29 (endoplasmic reticulum protein 29)

2007-02-01  

Identity

HGNC
LOCATION
12q24.13
LOCUSID
ALIAS
C12orf8,ERp28,ERp31,HEL-S-107,PDI-DB,PDIA9
FUSION GENES

Other Information

Locus ID:

NCBI: 10961
MIM: 602287
HGNC: 13799
Ensembl: ENSG00000089248

Variants:

dbSNP: 10961
ClinVar: 10961
TCGA: ENSG00000089248
COSMIC: ERP29

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000089248ENST00000261735P30040
ENSG00000089248ENST00000261735V9HW71
ENSG00000089248ENST00000455836P30040
ENSG00000089248ENST00000546477F8VY02
ENSG00000089248ENST00000552052F8W1G0

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Protein processing in endoplasmic reticulumKEGGko04141
Protein processing in endoplasmic reticulumKEGGhsa04141

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
178814352007A chaperone-activated nonenveloped virus perforates the physiologically relevant endoplasmic reticulum membrane.39
193216662009ERp29 restricts Connexin43 oligomerization in the endoplasmic reticulum.32
209205932011Endoplasmic reticulum protein 29 (ERp29): An emerging role in cancer.21
166770782006ERp29, an unusual redox-inactive member of the thioredoxin family.19
197708392009Overexpression of endoplasmic reticulum protein 29 regulates mesenchymal-epithelial transition and suppresses xenograft tumor growth of invasive breast cancer cells.17
219033682012Eurycomanone suppresses expression of lung cancer cell tumor markers, prohibitin, annexin 1 and endoplasmic reticulum protein 28.17
215250082011ERp29 regulates DeltaF508 and wild-type cystic fibrosis transmembrane conductance regulator (CFTR) trafficking to the plasma membrane in cystic fibrosis (CF) and non-CF epithelial cells.16
249166952014CLIC4, ERp29, and Smac/DIABLO derived from metastatic cancer stem-like cells stratify prognostic risks of colorectal cancer.16
190845382009Crystal structure and functional analysis of the protein disulfide isomerase-related protein ERp29.14
220643212012ERp29 induces breast cancer cell growth arrest and survival through modulation of activation of p38 and upregulation of ER stress protein p58IPK.14

Citation

Dessen P

ERP29 (endoplasmic reticulum protein 29)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46162/erp29