ERP44 (endoplasmic reticulum protein 44)

2014-08-01  

Identity

HGNC
LOCATION
9q31.1
LOCUSID
ALIAS
PDIA10,TXNDC4
FUSION GENES

Other Information

Locus ID:

NCBI: 23071
MIM: 609170
HGNC: 18311
Ensembl: ENSG00000023318

Variants:

dbSNP: 23071
ClinVar: 23071
TCGA: ENSG00000023318
COSMIC: ERP44

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000023318ENST00000262455Q9BS26
ENSG00000023318ENST00000262455A0A384MEE7

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
118471302002ERp44, a novel endoplasmic reticulum folding assistant of the thioredoxin family.63
178053462007Sequential steps and checkpoints in the early exocytic compartment during secretory IgM biogenesis.46
166770732006Dynamic retention of Ero1alpha and Ero1beta in the endoplasmic reticulum by interactions with PDI and ERp44.36
236850742013A pH-regulated quality control cycle for surveillance of secretory protein assembly.29
185088572008Multistep, sequential control of the trafficking and function of the multiple sulfatase deficiency gene product, SUMF1 by PDI, ERGIC-53 and ERp44.23
185527682008Crystal structure of human ERp44 shows a dynamic functional modulation by its carboxy-terminal tail.22
239791382013Dynamic regulation of Ero1α and peroxiredoxin 4 localization in the secretory pathway.19
181785492008ERp44 mediates a thiol-independent retention of formylglycine-generating enzyme in the endoplasmic reticulum.14
250972282014Progressive quality control of secretory proteins in the early secretory compartment by ERp44.13

Citation

Dessen P

ERP44 (endoplasmic reticulum protein 44)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54289/erp44