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ERVFRD-1 (endogenous retrovirus group FRD member 1, envelope)

Identity

Alias_namesendogenous retrovirus group FRD
Alias_symbol (synonym)HERV-W/FRD
HERV-FRD
envFRD
ERVFRDE1
syncytin-2
Other aliasGLLL6191
UNQ6191
HGNC (Hugo) ERVFRD-1
LocusID (NCBI) 405754
Atlas_Id 56408
Location 6p24.2  [Link to chromosome band 6p24]
Location_base_pair Starts at 11102489 and ends at 11111838 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NOL7 (6p23) / ERVFRD-1 (6p24.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;6)(p23;p24) NOL7/ERVFRD-1


External links

Nomenclature
HGNC (Hugo)ERVFRD-1   33823
Cards
Entrez_Gene (NCBI)ERVFRD-1  405754  endogenous retrovirus group FRD member 1, envelope
AliasesERVFRDE1; GLLL6191; HERV-FRD; HERV-W/FRD; 
UNQ6191; envFRD
GeneCards (Weizmann)ERVFRD-1
Ensembl hg19 (Hinxton)ENSG00000244476 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000244476 [Gene_View]  ENSG00000244476 [Sequence]  chr6:11102489-11111838 [Contig_View]  ERVFRD-1 [Vega]
ICGC DataPortalENSG00000244476
TCGA cBioPortalERVFRD-1
AceView (NCBI)ERVFRD-1
Genatlas (Paris)ERVFRD-1
WikiGenes405754
SOURCE (Princeton)ERVFRD-1
Genetics Home Reference (NIH)ERVFRD-1
Genomic and cartography
GoldenPath hg38 (UCSC)ERVFRD-1  -     chr6:11102489-11111838 -  6p24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ERVFRD-1  -     6p24.2   [Description]    (hg19-Feb_2009)
EnsemblERVFRD-1 - 6p24.2 [CytoView hg19]  ERVFRD-1 - 6p24.2 [CytoView hg38]
Mapping of homologs : NCBIERVFRD-1 [Mapview hg19]  ERVFRD-1 [Mapview hg38]
OMIM610524   
Gene and transcription
Genbank (Entrez)AK075092 AK123938 AY358244 BC068585 DA863475
RefSeq transcript (Entrez)NM_207582
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ERVFRD-1
Cluster EST : UnigeneHs.631996 [ NCBI ]
CGAP (NCI)Hs.631996
Alternative Splicing GalleryENSG00000244476
Gene ExpressionERVFRD-1 [ NCBI-GEO ]   ERVFRD-1 [ EBI - ARRAY_EXPRESS ]   ERVFRD-1 [ SEEK ]   ERVFRD-1 [ MEM ]
Gene Expression Viewer (FireBrowse)ERVFRD-1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)405754
GTEX Portal (Tissue expression)ERVFRD-1
Human Protein AtlasENSG00000244476-ERVFRD-1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP60508   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP60508  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP60508
Splice isoforms : SwissVarP60508
PhosPhoSitePlusP60508
Domains : Interpro (EBI)TLV/ENV_coat_polyprotein   
Domain families : Pfam (Sanger)TLV_coat (PF00429)   
Domain families : Pfam (NCBI)pfam00429   
Conserved Domain (NCBI)ERVFRD-1
DMDM Disease mutations405754
Blocks (Seattle)ERVFRD-1
PDB (SRS)1Y4M   
PDB (PDBSum)1Y4M   
PDB (IMB)1Y4M   
PDB (RSDB)1Y4M   
Structural Biology KnowledgeBase1Y4M   
SCOP (Structural Classification of Proteins)1Y4M   
CATH (Classification of proteins structures)1Y4M   
SuperfamilyP60508
Human Protein Atlas [tissue]ENSG00000244476-ERVFRD-1 [tissue]
Peptide AtlasP60508
HPRD13648
IPIIPI00398064   
Protein Interaction databases
DIP (DOE-UCLA)P60508
IntAct (EBI)P60508
FunCoupENSG00000244476
BioGRIDERVFRD-1
STRING (EMBL)ERVFRD-1
ZODIACERVFRD-1
Ontologies - Pathways
QuickGOP60508
Ontology : AmiGOsyncytium formation by plasma membrane fusion  plasma membrane  syncytium formation  integral component of membrane  
Ontology : EGO-EBIsyncytium formation by plasma membrane fusion  plasma membrane  syncytium formation  integral component of membrane  
NDEx NetworkERVFRD-1
Atlas of Cancer Signalling NetworkERVFRD-1
Wikipedia pathwaysERVFRD-1
Orthology - Evolution
OrthoDB405754
GeneTree (enSembl)ENSG00000244476
Phylogenetic Trees/Animal Genes : TreeFamERVFRD-1
HOVERGENP60508
HOGENOMP60508
Homologs : HomoloGeneERVFRD-1
Homology/Alignments : Family Browser (UCSC)ERVFRD-1
Gene fusions - Rearrangements
Fusion : QuiverERVFRD-1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerERVFRD-1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ERVFRD-1
dbVarERVFRD-1
ClinVarERVFRD-1
1000_GenomesERVFRD-1 
Exome Variant ServerERVFRD-1
ExAC (Exome Aggregation Consortium)ENSG00000244476
GNOMAD BrowserENSG00000244476
Varsome BrowserERVFRD-1
Genetic variants : HAPMAP405754
Genomic Variants (DGV)ERVFRD-1 [DGVbeta]
DECIPHERERVFRD-1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisERVFRD-1 
Mutations
ICGC Data PortalERVFRD-1 
TCGA Data PortalERVFRD-1 
Broad Tumor PortalERVFRD-1
OASIS PortalERVFRD-1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICERVFRD-1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDERVFRD-1
BioMutasearch ERVFRD-1
DgiDB (Drug Gene Interaction Database)ERVFRD-1
DoCM (Curated mutations)ERVFRD-1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ERVFRD-1 (select a term)
intoGenERVFRD-1
Cancer3DERVFRD-1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610524   
Orphanet
DisGeNETERVFRD-1
MedgenERVFRD-1
Genetic Testing Registry ERVFRD-1
NextProtP60508 [Medical]
TSGene405754
GENETestsERVFRD-1
Target ValidationERVFRD-1
Huge Navigator ERVFRD-1 [HugePedia]
snp3D : Map Gene to Disease405754
BioCentury BCIQERVFRD-1
ClinGenERVFRD-1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD405754
Clinical trialERVFRD-1
Miscellaneous
canSAR (ICR)ERVFRD-1 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineERVFRD-1
EVEXERVFRD-1
GoPubMedERVFRD-1
iHOPERVFRD-1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:05:04 CET 2018

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