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ERVK-11 (endogenous retrovirus group K member 11)

Identity

Alias_namesendogenous retrovirus group K, member 11
Alias_symbol (synonym)c3_E
N8.4
Other aliaspolymerase
HGNC (Hugo) ERVK-11
LocusID (NCBI) 100862688
Atlas_Id 79587
Location 3q27.2  [Link to chromosome band 3q27]
Location_base_pair Starts at 185566059 and ends at 185567846 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)ERVK-11   39006
Cards
Entrez_Gene (NCBI)ERVK-11  100862688  endogenous retrovirus group K member 11
AliasesN8.4; c3_E; polymerase
GeneCards (Weizmann)ERVK-11
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr3:185566059-185567846 [Contig_View]  ERVK-11 [Vega]
TCGA cBioPortalERVK-11
AceView (NCBI)ERVK-11
Genatlas (Paris)ERVK-11
WikiGenes100862688
SOURCE (Princeton)ERVK-11
Genetics Home Reference (NIH)ERVK-11
Genomic and cartography
GoldenPath hg38 (UCSC)ERVK-11  -     chr3:185566059-185567846 -  3q27.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ERVK-11  -     3q27.2   [Description]    (hg19-Feb_2009)
EnsemblERVK-11 - 3q27.2 [CytoView hg19]  ERVK-11 - 3q27.2 [CytoView hg38]
Mapping of homologs : NCBIERVK-11 [Mapview hg19]  ERVK-11 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF080229 EF153348 FN806833 U87590
RefSeq transcript (Entrez)
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ERVK-11
Gene ExpressionERVK-11 [ NCBI-GEO ]   ERVK-11 [ EBI - ARRAY_EXPRESS ]   ERVK-11 [ SEEK ]   ERVK-11 [ MEM ]
Gene Expression Viewer (FireBrowse)ERVK-11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)100862688
GTEX Portal (Tissue expression)ERVK-11
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UQG0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UQG0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UQG0
Splice isoforms : SwissVarQ9UQG0
Catalytic activity : Enzyme2.7.7.49 [ Enzyme-Expasy ]   2.7.7.492.7.7.49 [ IntEnz-EBI ]   2.7.7.49 [ BRENDA ]   2.7.7.49 [ KEGG ]   
PhosPhoSitePlusQ9UQG0
Domaine pattern : Prosite (Expaxy)INTEGRASE (PS50994)    INTEGRASE_DBD (PS51027)    RNASE_H (PS50879)    RT_POL (PS50878)    ZF_INTEGRASE (PS50876)   
Domains : Interpro (EBI)HERV-K_env    Integrase_C_retrovir    Integrase_cat-core    Integrase_Zn-bd_dom-like_N    Integrase_Zn-bd_dom_N    RNaseH-like_dom    RNaseH_domain    RT_dom    RVT_thumb   
Domain families : Pfam (Sanger)HERV-K_env_2 (PF13804)    IN_DBD_C (PF00552)    Integrase_Zn (PF02022)    RNase_H (PF00075)    rve (PF00665)    RVT_1 (PF00078)    RVT_thumb (PF06817)   
Domain families : Pfam (NCBI)pfam13804    pfam00552    pfam02022    pfam00075    pfam00665    pfam00078    pfam06817   
Conserved Domain (NCBI)ERVK-11
DMDM Disease mutations100862688
Blocks (Seattle)ERVK-11
SuperfamilyQ9UQG0
Peptide AtlasQ9UQG0
Protein Interaction databases
DIP (DOE-UCLA)Q9UQG0
IntAct (EBI)Q9UQG0
BioGRIDERVK-11
STRING (EMBL)ERVK-11
ZODIACERVK-11
Ontologies - Pathways
QuickGOQ9UQG0
Ontology : AmiGODNA binding  RNA-directed DNA polymerase activity  RNA-DNA hybrid ribonuclease activity  RNA-dependent DNA biosynthetic process  DNA recombination  zinc ion binding  DNA integration  RNA phosphodiester bond hydrolysis, endonucleolytic  
Ontology : EGO-EBIDNA binding  RNA-directed DNA polymerase activity  RNA-DNA hybrid ribonuclease activity  RNA-dependent DNA biosynthetic process  DNA recombination  zinc ion binding  DNA integration  RNA phosphodiester bond hydrolysis, endonucleolytic  
NDEx NetworkERVK-11
Atlas of Cancer Signalling NetworkERVK-11
Wikipedia pathwaysERVK-11
Orthology - Evolution
OrthoDB100862688
Phylogenetic Trees/Animal Genes : TreeFamERVK-11
HOVERGENQ9UQG0
HOGENOMQ9UQG0
Homologs : HomoloGeneERVK-11
Homology/Alignments : Family Browser (UCSC)ERVK-11
Gene fusions - Rearrangements
Tumor Fusion PortalERVK-11
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerERVK-11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ERVK-11
dbVarERVK-11
ClinVarERVK-11
1000_GenomesERVK-11 
Exome Variant ServerERVK-11
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP100862688
Genomic Variants (DGV)ERVK-11 [DGVbeta]
DECIPHERERVK-11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisERVK-11 
Mutations
ICGC Data PortalERVK-11 
TCGA Data PortalERVK-11&Óbsp;|/TF>
Broad Tumor PortalERVK-11
OASIS PortalERVK-11 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDERVK-11
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ERVK-11
DgiDB (Drug Gene Interaction Database)ERVK-11
DoCM (Curated mutations)ERVK-11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ERVK-11 (select a term)
intoGenERVK-11
Cancer3DERVK-11(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETERVK-11
MedgenERVK-11
Genetic Testing Registry ERVK-11
NextProtQ9UQG0 [Medical]
TSGene100862688
GENETestsERVK-11
Target ValidationERVK-11
Huge Navigator ERVK-11 [HugePedia]
snp3D : Map Gene to Disease100862688
BioCentury BCIQERVK-11
ClinGenERVK-11
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD100862688
Clinical trialERVK-11
Miscellaneous
canSAR (ICR)ERVK-11 (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineERVK-11
EVEXERVK-11
GoPubMedERVK-11
iHOPERVK-11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:07:24 CET 2017

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