ESM1 (endothelial cell specific molecule 1)

2007-02-01  

Identity

HGNC
LOCATION
5q11.2
LOCUSID
ALIAS
endocan

Other Information

Locus ID:

NCBI: 11082
MIM: 601521
HGNC: 3466
Ensembl: ENSG00000164283

Variants:

dbSNP: 11082
ClinVar: 11082
TCGA: ENSG00000164283
COSMIC: ESM1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164283ENST00000381403Q9NQ30
ENSG00000164283ENST00000381405Q9NQ30
ENSG00000164283ENST00000601836M0R154

Expression (GTEx)

0
5
10
15

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
168996042006Endocan expression and relationship with survival in human non-small cell lung cancer.50
232430262013Endocan is upregulated on tumor vessels in invasive bladder cancer where it mediates VEGF-A-induced angiogenesis.45
186147592008Transcriptional profiling of VEGF-A and VEGF-C target genes in lymphatic endothelium reveals endothelial-specific molecule-1 as a novel mediator of lymphangiogenesis.39
173629272007Endocan is a VEGF-A and PI3K regulated gene with increased expression in human renal cancer.35
194585462009Endocan expression and localization in human glioblastomas.32
201023962010Vascular endocan (ESM-1) is markedly overexpressed in clear cell renal cell carcinoma.31
118665392002Identification of endothelial cell genes expressed in an in vitro model of angiogenesis: induction of ESM-1, (beta)ig-h3, and NrCAM.27
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
185923772009Endocan expression correlated with poor survival in human hepatocellular carcinoma.24

Citation

Dessen P

ESM1 (endothelial cell specific molecule 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46383/esm1