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ESR1 (estrogen receptor 1)

Identity

Alias_namesESR
Alias_symbol (synonym)NR3A1
Era
Other aliasER
ESRA
ESTRR
HGNC (Hugo) ESR1
LocusID (NCBI) 2099
Atlas_Id 40499
Location 6q25.1  [Link to chromosome band 6q25]
Location_base_pair Starts at 151809107 and ends at 152129603 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
E2F1 (20q11.22) / ESR1 (6q25.1)ESR1 (6q25.1) / ARMT1 (6q25.1)ESR1 (6q25.1) / ASPH (8q12.3)
ESR1 (6q25.1) / BNC2 (9p22.3)ESR1 (6q25.1) / CCDC170 (6q25.1)ESR1 (6q25.1) / LOC100287944 (12q23.3)
ESR1 (6q25.1) / MTHFD1L (6q25.1)ESR1 (6q25.1) / TFB1M (6q25.3)ESR1 (6q25.1) / USP25 (21q21.1)
FASN (17q25.3) / ESR1 (6q25.1)MALAT1 (11q13.1) / ESR1 (6q25.1)TULP4 (6q25.3) / ESR1 (6q25.1)
ESR1 6q25.1 / ASPH 8q12.3ESR1 6q25.1 / BNC2 9p22.3ESR1 6q25.1 C6orf211
ESR1 6q25.1 C6orf97ESR1 6q25.1 / MTHFD1L 6q25.1ESR1 6q25.1 / TFB1M 6q25.3
ESR1 6q25.1 / USP25 21q21.1TULP4 6q25.3 / ESR1 6q25.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 11 ]
  Breast: Ductal carcinoma
t(6;6)(q23;q25) MYB/ESR1
ESR1/ARMT1 (6q25)
ESR1/CCDC170 (6q25)
ESR1/MTHFD1L (6q25)
ESR1/TFB1M (6q25)
TULP4/ESR1 (6q25)
ESR1/CCDC170 (6q25)
t(6;8)(q25;q12) ESR1/ASPH
t(6;9)(q25;p22) ESR1/BNC2
t(6;21)(q25;q21) ESR1/USP25


Other Cancer prone implicated (Data extracted from papers in the Atlas) [ 1 ]
  Hereditary breast cancer


External links

Nomenclature
HGNC (Hugo)ESR1   3467
LRG (Locus Reference Genomic)LRG_992
Cards
Entrez_Gene (NCBI)ESR1  2099  estrogen receptor 1
AliasesER; ESR; ESRA; ESTRR; 
Era; NR3A1
GeneCards (Weizmann)ESR1
Ensembl hg19 (Hinxton)ENSG00000091831 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000091831 [Gene_View]  ENSG00000091831 [Sequence]  chr6:151809107-152129603 [Contig_View]  ESR1 [Vega]
ICGC DataPortalENSG00000091831
TCGA cBioPortalESR1
AceView (NCBI)ESR1
Genatlas (Paris)ESR1
WikiGenes2099
SOURCE (Princeton)ESR1
Genetics Home Reference (NIH)ESR1
Genomic and cartography
GoldenPath hg38 (UCSC)ESR1  -     chr6:151809107-152129603 +  6q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ESR1  -     6q25.1   [Description]    (hg19-Feb_2009)
EnsemblESR1 - 6q25.1 [CytoView hg19]  ESR1 - 6q25.1 [CytoView hg38]
Mapping of homologs : NCBIESR1 [Mapview hg19]  ESR1 [Mapview hg38]
OMIM114480   133430   157300   608446   615363   
Gene and transcription
Genbank (Entrez)AB307713 AB588629 AB588630 AB685814 AB685815
RefSeq transcript (Entrez)NM_000125 NM_001122740 NM_001122741 NM_001122742 NM_001291230 NM_001291241 NM_001328100
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ESR1
Cluster EST : UnigeneHs.744830 [ NCBI ]
CGAP (NCI)Hs.744830
Alternative Splicing GalleryENSG00000091831
Gene ExpressionESR1 [ NCBI-GEO ]   ESR1 [ EBI - ARRAY_EXPRESS ]   ESR1 [ SEEK ]   ESR1 [ MEM ]
Gene Expression Viewer (FireBrowse)ESR1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2099
GTEX Portal (Tissue expression)ESR1
Human Protein AtlasENSG00000091831-ESR1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP03372   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP03372  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP03372
Splice isoforms : SwissVarP03372
PhosPhoSitePlusP03372
Domaine pattern : Prosite (Expaxy)NR_LBD (PS51843)    NUCLEAR_REC_DBD_1 (PS00031)    NUCLEAR_REC_DBD_2 (PS51030)   
Domains : Interpro (EBI)NHR_like_dom_sf    Nucl_hrmn_rcpt_lig-bd    Nuclear_hrmn_rcpt    Oest_rcpt/oest-rel_rcp    Oestr_rcpt    Oestrogen-typ_rcpt_final_C_dom    Znf_hrmn_rcpt    Znf_NHR/GATA   
Domain families : Pfam (Sanger)ESR1_C (PF12743)    Hormone_recep (PF00104)    Oest_recep (PF02159)    zf-C4 (PF00105)   
Domain families : Pfam (NCBI)pfam12743    pfam00104    pfam02159    pfam00105   
Domain families : Smart (EMBL)HOLI (SM00430)  ZnF_C4 (SM00399)  
Conserved Domain (NCBI)ESR1
DMDM Disease mutations2099
Blocks (Seattle)ESR1
PDB (SRS)1A52    1AKF    1ERE    1ERR    1G50    1GWQ    1GWR    1HCP    1HCQ    1L2I    1PCG    1QKT    1QKU    1R5K    1SJ0    1UOM    1X7E    1X7R    1XP1    1XP6    1XP9    1XPC    1XQC    1YIM    1YIN    1ZKY    2AYR    2B1V    2B1Z    2B23    2BJ4    2FAI    2G44    2G5O    2I0J    2IOG    2IOK    2JF9    2JFA    2LLO    2LLQ    2OCF    2OUZ    2P15    2POG    2Q6J    2Q70    2QA6    2QA8    2QAB    2QE4    2QGT    2QGW    2QH6    2QR9    2QSE    2QXM    2QXS    2QZO    2R6W    2R6Y    2YAT    2YJA    3CBM    3CBO    3CBP    3DT3    3ERD    3ERT    3HLV    3HM1    3L03    3OS8    3OS9    3OSA    3Q95    3UU7    3UUA    3UUC    3UUD    4AA6    4DMA    4IU7    4IUI    4IV2    4IV4    4IVW    4IVY    4IW6    4IW8    4IWC    4IWF    4JC3    4JDD    4MG5    4MG6    4MG7    4MG8    4MG9    4MGA    4MGB    4MGC    4MGD    4O6F    4PP6    4PPP    4PPS    4PXM    4Q13    4Q50    4TUZ    4TV1    4XI3    4ZN7    4ZN9    4ZNH    4ZNS    4ZNT    4ZNU    4ZNV    4ZNW    5AAU    5AAV    5ACC    5AK2    5DI7    5DID    5DIE    5DIG    5DK9    5DKB    5DKE    5DKG    5DKS    5DL4    5DLR    5DMC    5DMF    5DP0    5DRJ    5DRM    5DTV    5DU5    5DUE    5DUG    5DUH    5DVS    5DVV    5DWE    5DWG    5DWI    5DWJ    5DX3    5DXB    5DXE    5DXG    5DXK    5DXM    5DXP    5DXQ    5DXR    5DY8    5DYB    5DYD    5DZ0    5DZ1    5DZ3    5DZH    5DZI    5E0W    5E0X    5E14    5E15    5E19    5E1C    5EGV    5EHJ    5EI1    5EIT    5FQP    5FQR    5FQS    5FQT    5FQV    5GS4    5GTR    5HYR    5JMM    5KCC    5KCD    5KCE    5KCF    5KCT    5KCU    5KCW    5KD9    5KR9    5KRA    5KRC    5KRF    5KRH    5KRI    5KRJ    5KRK    5KRL    5KRM    5KRO    5N10    5T0X    5T1Z    5T92    5T97    5TLD    5TLF    5TLG    5TLL    5TLM    5TLO    5TLP    5TLT    5TLU    5TLV    5TLX    5TLY    5TM1    5TM2    5TM3    5TM4    5TM5    5TM6    5TM7    5TM8    5TM9    5TML    5TMM    5TMO    5TMQ    5TMR    5TMS    5TMT    5TMU    5TMV    5TMW    5TMZ    5TN1    5TN3    5TN4    5TN5    5TN6    5TN7    5TN8    5TN9    5TNB    5U2B    5U2D    5UFW    5UFX    5W9D    6C42    6CBZ   
PDB (PDBSum)1A52    1AKF    1ERE    1ERR    1G50    1GWQ    1GWR    1HCP    1HCQ    1L2I    1PCG    1QKT    1QKU    1R5K    1SJ0    1UOM    1X7E    1X7R    1XP1    1XP6    1XP9    1XPC    1XQC    1YIM    1YIN    1ZKY    2AYR    2B1V    2B1Z    2B23    2BJ4    2FAI    2G44    2G5O    2I0J    2IOG    2IOK    2JF9    2JFA    2LLO    2LLQ    2OCF    2OUZ    2P15    2POG    2Q6J    2Q70    2QA6    2QA8    2QAB    2QE4    2QGT    2QGW    2QH6    2QR9    2QSE    2QXM    2QXS    2QZO    2R6W    2R6Y    2YAT    2YJA    3CBM    3CBO    3CBP    3DT3    3ERD    3ERT    3HLV    3HM1    3L03    3OS8    3OS9    3OSA    3Q95    3UU7    3UUA    3UUC    3UUD    4AA6    4DMA    4IU7    4IUI    4IV2    4IV4    4IVW    4IVY    4IW6    4IW8    4IWC    4IWF    4JC3    4JDD    4MG5    4MG6    4MG7    4MG8    4MG9    4MGA    4MGB    4MGC    4MGD    4O6F    4PP6    4PPP    4PPS    4PXM    4Q13    4Q50    4TUZ    4TV1    4XI3    4ZN7    4ZN9    4ZNH    4ZNS    4ZNT    4ZNU    4ZNV    4ZNW    5AAU    5AAV    5ACC    5AK2    5DI7    5DID    5DIE    5DIG    5DK9    5DKB    5DKE    5DKG    5DKS    5DL4    5DLR    5DMC    5DMF    5DP0    5DRJ    5DRM    5DTV    5DU5    5DUE    5DUG    5DUH    5DVS    5DVV    5DWE    5DWG    5DWI    5DWJ    5DX3    5DXB    5DXE    5DXG    5DXK    5DXM    5DXP    5DXQ    5DXR    5DY8    5DYB    5DYD    5DZ0    5DZ1    5DZ3    5DZH    5DZI    5E0W    5E0X    5E14    5E15    5E19    5E1C    5EGV    5EHJ    5EI1    5EIT    5FQP    5FQR    5FQS    5FQT    5FQV    5GS4    5GTR    5HYR    5JMM    5KCC    5KCD    5KCE    5KCF    5KCT    5KCU    5KCW    5KD9    5KR9    5KRA    5KRC    5KRF    5KRH    5KRI    5KRJ    5KRK    5KRL    5KRM    5KRO    5N10    5T0X    5T1Z    5T92    5T97    5TLD    5TLF    5TLG    5TLL    5TLM    5TLO    5TLP    5TLT    5TLU    5TLV    5TLX    5TLY    5TM1    5TM2    5TM3    5TM4    5TM5    5TM6    5TM7    5TM8    5TM9    5TML    5TMM    5TMO    5TMQ    5TMR    5TMS    5TMT    5TMU    5TMV    5TMW    5TMZ    5TN1    5TN3    5TN4    5TN5    5TN6    5TN7    5TN8    5TN9    5TNB    5U2B    5U2D    5UFW    5UFX    5W9D    6C42    6CBZ   
PDB (IMB)1A52    1AKF    1ERE    1ERR    1G50    1GWQ    1GWR    1HCP    1HCQ    1L2I    1PCG    1QKT    1QKU    1R5K    1SJ0    1UOM    1X7E    1X7R    1XP1    1XP6    1XP9    1XPC    1XQC    1YIM    1YIN    1ZKY    2AYR    2B1V    2B1Z    2B23    2BJ4    2FAI    2G44    2G5O    2I0J    2IOG    2IOK    2JF9    2JFA    2LLO    2LLQ    2OCF    2OUZ    2P15    2POG    2Q6J    2Q70    2QA6    2QA8    2QAB    2QE4    2QGT    2QGW    2QH6    2QR9    2QSE    2QXM    2QXS    2QZO    2R6W    2R6Y    2YAT    2YJA    3CBM    3CBO    3CBP    3DT3    3ERD    3ERT    3HLV    3HM1    3L03    3OS8    3OS9    3OSA    3Q95    3UU7    3UUA    3UUC    3UUD    4AA6    4DMA    4IU7    4IUI    4IV2    4IV4    4IVW    4IVY    4IW6    4IW8    4IWC    4IWF    4JC3    4JDD    4MG5    4MG6    4MG7    4MG8    4MG9    4MGA    4MGB    4MGC    4MGD    4O6F    4PP6    4PPP    4PPS    4PXM    4Q13    4Q50    4TUZ    4TV1    4XI3    4ZN7    4ZN9    4ZNH    4ZNS    4ZNT    4ZNU    4ZNV    4ZNW    5AAU    5AAV    5ACC    5AK2    5DI7    5DID    5DIE    5DIG    5DK9    5DKB    5DKE    5DKG    5DKS    5DL4    5DLR    5DMC    5DMF    5DP0    5DRJ    5DRM    5DTV    5DU5    5DUE    5DUG    5DUH    5DVS    5DVV    5DWE    5DWG    5DWI    5DWJ    5DX3    5DXB    5DXE    5DXG    5DXK    5DXM    5DXP    5DXQ    5DXR    5DY8    5DYB    5DYD    5DZ0    5DZ1    5DZ3    5DZH    5DZI    5E0W    5E0X    5E14    5E15    5E19    5E1C    5EGV    5EHJ    5EI1    5EIT    5FQP    5FQR    5FQS    5FQT    5FQV    5GS4    5GTR    5HYR    5JMM    5KCC    5KCD    5KCE    5KCF    5KCT    5KCU    5KCW    5KD9    5KR9    5KRA    5KRC    5KRF    5KRH    5KRI    5KRJ    5KRK    5KRL    5KRM    5KRO    5N10    5T0X    5T1Z    5T92    5T97    5TLD    5TLF    5TLG    5TLL    5TLM    5TLO    5TLP    5TLT    5TLU    5TLV    5TLX    5TLY    5TM1    5TM2    5TM3    5TM4    5TM5    5TM6    5TM7    5TM8    5TM9    5TML    5TMM    5TMO    5TMQ    5TMR    5TMS    5TMT    5TMU    5TMV    5TMW    5TMZ    5TN1    5TN3    5TN4    5TN5    5TN6    5TN7    5TN8    5TN9    5TNB    5U2B    5U2D    5UFW    5UFX    5W9D    6C42    6CBZ   
PDB (RSDB)1A52    1AKF    1ERE    1ERR    1G50    1GWQ    1GWR    1HCP    1HCQ    1L2I    1PCG    1QKT    1QKU    1R5K    1SJ0    1UOM    1X7E    1X7R    1XP1    1XP6    1XP9    1XPC    1XQC    1YIM    1YIN    1ZKY    2AYR    2B1V    2B1Z    2B23    2BJ4    2FAI    2G44    2G5O    2I0J    2IOG    2IOK    2JF9    2JFA    2LLO    2LLQ    2OCF    2OUZ    2P15    2POG    2Q6J    2Q70    2QA6    2QA8    2QAB    2QE4    2QGT    2QGW    2QH6    2QR9    2QSE    2QXM    2QXS    2QZO    2R6W    2R6Y    2YAT    2YJA    3CBM    3CBO    3CBP    3DT3    3ERD    3ERT    3HLV    3HM1    3L03    3OS8    3OS9    3OSA    3Q95    3UU7    3UUA    3UUC    3UUD    4AA6    4DMA    4IU7    4IUI    4IV2    4IV4    4IVW    4IVY    4IW6    4IW8    4IWC    4IWF    4JC3    4JDD    4MG5    4MG6    4MG7    4MG8    4MG9    4MGA    4MGB    4MGC    4MGD    4O6F    4PP6    4PPP    4PPS    4PXM    4Q13    4Q50    4TUZ    4TV1    4XI3    4ZN7    4ZN9    4ZNH    4ZNS    4ZNT    4ZNU    4ZNV    4ZNW    5AAU    5AAV    5ACC    5AK2    5DI7    5DID    5DIE    5DIG    5DK9    5DKB    5DKE    5DKG    5DKS    5DL4    5DLR    5DMC    5DMF    5DP0    5DRJ    5DRM    5DTV    5DU5    5DUE    5DUG    5DUH    5DVS    5DVV    5DWE    5DWG    5DWI    5DWJ    5DX3    5DXB    5DXE    5DXG    5DXK    5DXM    5DXP    5DXQ    5DXR    5DY8    5DYB    5DYD    5DZ0    5DZ1    5DZ3    5DZH    5DZI    5E0W    5E0X    5E14    5E15    5E19    5E1C    5EGV    5EHJ    5EI1    5EIT    5FQP    5FQR    5FQS    5FQT    5FQV    5GS4    5GTR    5HYR    5JMM    5KCC    5KCD    5KCE    5KCF    5KCT    5KCU    5KCW    5KD9    5KR9    5KRA    5KRC    5KRF    5KRH    5KRI    5KRJ    5KRK    5KRL    5KRM    5KRO    5N10    5T0X    5T1Z    5T92    5T97    5TLD    5TLF    5TLG    5TLL    5TLM    5TLO    5TLP    5TLT    5TLU    5TLV    5TLX    5TLY    5TM1    5TM2    5TM3    5TM4    5TM5    5TM6    5TM7    5TM8    5TM9    5TML    5TMM    5TMO    5TMQ    5TMR    5TMS    5TMT    5TMU    5TMV    5TMW    5TMZ    5TN1    5TN3    5TN4    5TN5    5TN6    5TN7    5TN8    5TN9    5TNB    5U2B    5U2D    5UFW    5UFX    5W9D    6C42    6CBZ   
Structural Biology KnowledgeBase1A52    1AKF    1ERE    1ERR    1G50    1GWQ    1GWR    1HCP    1HCQ    1L2I    1PCG    1QKT    1QKU    1R5K    1SJ0    1UOM    1X7E    1X7R    1XP1    1XP6    1XP9    1XPC    1XQC    1YIM    1YIN    1ZKY    2AYR    2B1V    2B1Z    2B23    2BJ4    2FAI    2G44    2G5O    2I0J    2IOG    2IOK    2JF9    2JFA    2LLO    2LLQ    2OCF    2OUZ    2P15    2POG    2Q6J    2Q70    2QA6    2QA8    2QAB    2QE4    2QGT    2QGW    2QH6    2QR9    2QSE    2QXM    2QXS    2QZO    2R6W    2R6Y    2YAT    2YJA    3CBM    3CBO    3CBP    3DT3    3ERD    3ERT    3HLV    3HM1    3L03    3OS8    3OS9    3OSA    3Q95    3UU7    3UUA    3UUC    3UUD    4AA6    4DMA    4IU7    4IUI    4IV2    4IV4    4IVW    4IVY    4IW6    4IW8    4IWC    4IWF    4JC3    4JDD    4MG5    4MG6    4MG7    4MG8    4MG9    4MGA    4MGB    4MGC    4MGD    4O6F    4PP6    4PPP    4PPS    4PXM    4Q13    4Q50    4TUZ    4TV1    4XI3    4ZN7    4ZN9    4ZNH    4ZNS    4ZNT    4ZNU    4ZNV    4ZNW    5AAU    5AAV    5ACC    5AK2    5DI7    5DID    5DIE    5DIG    5DK9    5DKB    5DKE    5DKG    5DKS    5DL4    5DLR    5DMC    5DMF    5DP0    5DRJ    5DRM    5DTV    5DU5    5DUE    5DUG    5DUH    5DVS    5DVV    5DWE    5DWG    5DWI    5DWJ    5DX3    5DXB    5DXE    5DXG    5DXK    5DXM    5DXP    5DXQ    5DXR    5DY8    5DYB    5DYD    5DZ0    5DZ1    5DZ3    5DZH    5DZI    5E0W    5E0X    5E14    5E15    5E19    5E1C    5EGV    5EHJ    5EI1    5EIT    5FQP    5FQR    5FQS    5FQT    5FQV    5GS4    5GTR    5HYR    5JMM    5KCC    5KCD    5KCE    5KCF    5KCT    5KCU    5KCW    5KD9    5KR9    5KRA    5KRC    5KRF    5KRH    5KRI    5KRJ    5KRK    5KRL    5KRM    5KRO    5N10    5T0X    5T1Z    5T92    5T97    5TLD    5TLF    5TLG    5TLL    5TLM    5TLO    5TLP    5TLT    5TLU    5TLV    5TLX    5TLY    5TM1    5TM2    5TM3    5TM4    5TM5    5TM6    5TM7    5TM8    5TM9    5TML    5TMM    5TMO    5TMQ    5TMR    5TMS    5TMT    5TMU    5TMV    5TMW    5TMZ    5TN1    5TN3    5TN4    5TN5    5TN6    5TN7    5TN8    5TN9    5TNB    5U2B    5U2D    5UFW    5UFX    5W9D    6C42    6CBZ   
SCOP (Structural Classification of Proteins)1A52    1AKF    1ERE    1ERR    1G50    1GWQ    1GWR    1HCP    1HCQ    1L2I    1PCG    1QKT    1QKU    1R5K    1SJ0    1UOM    1X7E    1X7R    1XP1    1XP6    1XP9    1XPC    1XQC    1YIM    1YIN    1ZKY    2AYR    2B1V    2B1Z    2B23    2BJ4    2FAI    2G44    2G5O    2I0J    2IOG    2IOK    2JF9    2JFA    2LLO    2LLQ    2OCF    2OUZ    2P15    2POG    2Q6J    2Q70    2QA6    2QA8    2QAB    2QE4    2QGT    2QGW    2QH6    2QR9    2QSE    2QXM    2QXS    2QZO    2R6W    2R6Y    2YAT    2YJA    3CBM    3CBO    3CBP    3DT3    3ERD    3ERT    3HLV    3HM1    3L03    3OS8    3OS9    3OSA    3Q95    3UU7    3UUA    3UUC    3UUD    4AA6    4DMA    4IU7    4IUI    4IV2    4IV4    4IVW    4IVY    4IW6    4IW8    4IWC    4IWF    4JC3    4JDD    4MG5    4MG6    4MG7    4MG8    4MG9    4MGA    4MGB    4MGC    4MGD    4O6F    4PP6    4PPP    4PPS    4PXM    4Q13    4Q50    4TUZ    4TV1    4XI3    4ZN7    4ZN9    4ZNH    4ZNS    4ZNT    4ZNU    4ZNV    4ZNW    5AAU    5AAV    5ACC    5AK2    5DI7    5DID    5DIE    5DIG    5DK9    5DKB    5DKE    5DKG    5DKS    5DL4    5DLR    5DMC    5DMF    5DP0    5DRJ    5DRM    5DTV    5DU5    5DUE    5DUG    5DUH    5DVS    5DVV    5DWE    5DWG    5DWI    5DWJ    5DX3    5DXB    5DXE    5DXG    5DXK    5DXM    5DXP    5DXQ    5DXR    5DY8    5DYB    5DYD    5DZ0    5DZ1    5DZ3    5DZH    5DZI    5E0W    5E0X    5E14    5E15    5E19    5E1C    5EGV    5EHJ    5EI1    5EIT    5FQP    5FQR    5FQS    5FQT    5FQV    5GS4    5GTR    5HYR    5JMM    5KCC    5KCD    5KCE    5KCF    5KCT    5KCU    5KCW    5KD9    5KR9    5KRA    5KRC    5KRF    5KRH    5KRI    5KRJ    5KRK    5KRL    5KRM    5KRO    5N10    5T0X    5T1Z    5T92    5T97    5TLD    5TLF    5TLG    5TLL    5TLM    5TLO    5TLP    5TLT    5TLU    5TLV    5TLX    5TLY    5TM1    5TM2    5TM3    5TM4    5TM5    5TM6    5TM7    5TM8    5TM9    5TML    5TMM    5TMO    5TMQ    5TMR    5TMS    5TMT    5TMU    5TMV    5TMW    5TMZ    5TN1    5TN3    5TN4    5TN5    5TN6    5TN7    5TN8    5TN9    5TNB    5U2B    5U2D    5UFW    5UFX    5W9D    6C42    6CBZ   
CATH (Classification of proteins structures)1A52    1AKF    1ERE    1ERR    1G50    1GWQ    1GWR    1HCP    1HCQ    1L2I    1PCG    1QKT    1QKU    1R5K    1SJ0    1UOM    1X7E    1X7R    1XP1    1XP6    1XP9    1XPC    1XQC    1YIM    1YIN    1ZKY    2AYR    2B1V    2B1Z    2B23    2BJ4    2FAI    2G44    2G5O    2I0J    2IOG    2IOK    2JF9    2JFA    2LLO    2LLQ    2OCF    2OUZ    2P15    2POG    2Q6J    2Q70    2QA6    2QA8    2QAB    2QE4    2QGT    2QGW    2QH6    2QR9    2QSE    2QXM    2QXS    2QZO    2R6W    2R6Y    2YAT    2YJA    3CBM    3CBO    3CBP    3DT3    3ERD    3ERT    3HLV    3HM1    3L03    3OS8    3OS9    3OSA    3Q95    3UU7    3UUA    3UUC    3UUD    4AA6    4DMA    4IU7    4IUI    4IV2    4IV4    4IVW    4IVY    4IW6    4IW8    4IWC    4IWF    4JC3    4JDD    4MG5    4MG6    4MG7    4MG8    4MG9    4MGA    4MGB    4MGC    4MGD    4O6F    4PP6    4PPP    4PPS    4PXM    4Q13    4Q50    4TUZ    4TV1    4XI3    4ZN7    4ZN9    4ZNH    4ZNS    4ZNT    4ZNU    4ZNV    4ZNW    5AAU    5AAV    5ACC    5AK2    5DI7    5DID    5DIE    5DIG    5DK9    5DKB    5DKE    5DKG    5DKS    5DL4    5DLR    5DMC    5DMF    5DP0    5DRJ    5DRM    5DTV    5DU5    5DUE    5DUG    5DUH    5DVS    5DVV    5DWE    5DWG    5DWI    5DWJ    5DX3    5DXB    5DXE    5DXG    5DXK    5DXM    5DXP    5DXQ    5DXR    5DY8    5DYB    5DYD    5DZ0    5DZ1    5DZ3    5DZH    5DZI    5E0W    5E0X    5E14    5E15    5E19    5E1C    5EGV    5EHJ    5EI1    5EIT    5FQP    5FQR    5FQS    5FQT    5FQV    5GS4    5GTR    5HYR    5JMM    5KCC    5KCD    5KCE    5KCF    5KCT    5KCU    5KCW    5KD9    5KR9    5KRA    5KRC    5KRF    5KRH    5KRI    5KRJ    5KRK    5KRL    5KRM    5KRO    5N10    5T0X    5T1Z    5T92    5T97    5TLD    5TLF    5TLG    5TLL    5TLM    5TLO    5TLP    5TLT    5TLU    5TLV    5TLX    5TLY    5TM1    5TM2    5TM3    5TM4    5TM5    5TM6    5TM7    5TM8    5TM9    5TML    5TMM    5TMO    5TMQ    5TMR    5TMS    5TMT    5TMU    5TMV    5TMW    5TMZ    5TN1    5TN3    5TN4    5TN5    5TN6    5TN7    5TN8    5TN9    5TNB    5U2B    5U2D    5UFW    5UFX    5W9D    6C42    6CBZ   
SuperfamilyP03372
Human Protein Atlas [tissue]ENSG00000091831-ESR1 [tissue]
Peptide AtlasP03372
HPRD00589
IPIIPI00294982   IPI00218352   IPI01018719   IPI00807600   IPI00942862   IPI01025596   IPI00914846   IPI00969222   IPI00973132   IPI00914643   IPI00025064   IPI00922288   IPI01018934   IPI00914588   IPI00879773   IPI00902535   IPI00878052   
Protein Interaction databases
DIP (DOE-UCLA)P03372
IntAct (EBI)P03372
FunCoupENSG00000091831
BioGRIDESR1
STRING (EMBL)ESR1
ZODIACESR1
Ontologies - Pathways
QuickGOP03372
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  nuclear chromatin  RNA polymerase II proximal promoter sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific  TFIIB-class transcription factor binding  transcription coactivator binding  antral ovarian follicle growth  epithelial cell development  chromatin binding  DNA-binding transcription factor activity  steroid hormone receptor activity  steroid binding  protein binding  nucleus  nucleoplasm  cytoplasm  Golgi apparatus  cytosol  plasma membrane  chromatin remodeling  transcription, DNA-templated  regulation of transcription, DNA-templated  regulation of transcription by RNA polymerase II  transcription by RNA polymerase II  transcription initiation from RNA polymerase II promoter  signal transduction  phospholipase C-activating G protein-coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  beta-catenin binding  transcription factor binding  androgen metabolic process  zinc ion binding  male gonad development  negative regulation of gene expression  positive regulation of phospholipase C activity  membrane  integral component of membrane  protein deubiquitination  TBP-class protein binding  enzyme binding  protein kinase binding  regulation of Wnt signaling pathway  nitric-oxide synthase regulator activity  estrogen receptor activity  estrogen receptor activity  estrogen receptor activity  estrogen receptor binding  intracellular steroid hormone receptor signaling pathway  intracellular estrogen receptor signaling pathway  intracellular estrogen receptor signaling pathway  response to estradiol  protein-containing complex  regulation of intracellular estrogen receptor signaling pathway  estrogen response element binding  regulation of toll-like receptor signaling pathway  transcriptionally active chromatin  RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding  RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding  identical protein binding  regulation of apoptotic process  negative regulation of I-kappaB kinase/NF-kappaB signaling  negative regulation of DNA-binding transcription factor activity  response to estrogen  positive regulation of transcription, DNA-templated  positive regulation of RNA polymerase II transcriptional preinitiation complex assembly  positive regulation of transcription by RNA polymerase II  phosphatidylinositol phosphorylation  phosphatidylinositol-4,5-bisphosphate 3-kinase activity  positive regulation of fibroblast proliferation  stem cell differentiation  regulation of inflammatory response  positive regulation of DNA-binding transcription factor activity  ATPase binding  positive regulation of protein kinase B signaling  uterus development  vagina development  prostate epithelial cord elongation  prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis  regulation of branching involved in prostate gland morphogenesis  mammary gland branching involved in pregnancy  mammary gland alveolus development  epithelial cell proliferation involved in mammary gland duct elongation  protein localization to chromatin  cellular response to estrogen stimulus  cellular response to estradiol stimulus  cellular response to estradiol stimulus  transcriptional preinitiation complex  negative regulation of production of miRNAs involved in gene silencing by miRNA  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  nuclear chromatin  RNA polymerase II proximal promoter sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific  TFIIB-class transcription factor binding  transcription coactivator binding  antral ovarian follicle growth  epithelial cell development  chromatin binding  DNA-binding transcription factor activity  steroid hormone receptor activity  steroid binding  protein binding  nucleus  nucleoplasm  cytoplasm  Golgi apparatus  cytosol  plasma membrane  chromatin remodeling  transcription, DNA-templated  regulation of transcription, DNA-templated  regulation of transcription by RNA polymerase II  transcription by RNA polymerase II  transcription initiation from RNA polymerase II promoter  signal transduction  phospholipase C-activating G protein-coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  beta-catenin binding  transcription factor binding  androgen metabolic process  zinc ion binding  male gonad development  negative regulation of gene expression  positive regulation of phospholipase C activity  membrane  integral component of membrane  protein deubiquitination  TBP-class protein binding  enzyme binding  protein kinase binding  regulation of Wnt signaling pathway  nitric-oxide synthase regulator activity  estrogen receptor activity  estrogen receptor activity  estrogen receptor activity  estrogen receptor binding  intracellular steroid hormone receptor signaling pathway  intracellular estrogen receptor signaling pathway  intracellular estrogen receptor signaling pathway  response to estradiol  protein-containing complex  regulation of intracellular estrogen receptor signaling pathway  estrogen response element binding  regulation of toll-like receptor signaling pathway  transcriptionally active chromatin  RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding  RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding  identical protein binding  regulation of apoptotic process  negative regulation of I-kappaB kinase/NF-kappaB signaling  negative regulation of DNA-binding transcription factor activity  response to estrogen  positive regulation of transcription, DNA-templated  positive regulation of RNA polymerase II transcriptional preinitiation complex assembly  positive regulation of transcription by RNA polymerase II  phosphatidylinositol phosphorylation  phosphatidylinositol-4,5-bisphosphate 3-kinase activity  positive regulation of fibroblast proliferation  stem cell differentiation  regulation of inflammatory response  positive regulation of DNA-binding transcription factor activity  ATPase binding  positive regulation of protein kinase B signaling  uterus development  vagina development  prostate epithelial cord elongation  prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis  regulation of branching involved in prostate gland morphogenesis  mammary gland branching involved in pregnancy  mammary gland alveolus development  epithelial cell proliferation involved in mammary gland duct elongation  protein localization to chromatin  cellular response to estrogen stimulus  cellular response to estradiol stimulus  cellular response to estradiol stimulus  transcriptional preinitiation complex  negative regulation of production of miRNAs involved in gene silencing by miRNA  
Pathways : KEGGEstrogen signaling pathway    Prolactin signaling pathway    Thyroid hormone signaling pathway    Endocrine and other factor-regulated calcium reabsorption    Proteoglycans in cancer   
NDEx NetworkESR1
Atlas of Cancer Signalling NetworkESR1
Wikipedia pathwaysESR1
Orthology - Evolution
OrthoDB2099
GeneTree (enSembl)ENSG00000091831
Phylogenetic Trees/Animal Genes : TreeFamESR1
HOVERGENP03372
HOGENOMP03372
Homologs : HomoloGeneESR1
Homology/Alignments : Family Browser (UCSC)ESR1
Gene fusions - Rearrangements
Fusion : MitelmanESR1/ARMT1 [6q25.1/6q25.1]  
Fusion : MitelmanESR1/ASPH [6q25.1/8q12.3]  [t(6;8)(q25;q12)]  
Fusion : MitelmanESR1/BNC2 [6q25.1/9p22.3]  [t(6;9)(q25;p22)]  
Fusion : MitelmanESR1/CCDC170 [6q25.1/6q25.1]  [t(6;6)(q25;q25)]  
Fusion : MitelmanESR1/MTHFD1L [6q25.1/6q25.1]  [t(6;6)(q25;q25)]  
Fusion : MitelmanESR1/TFB1M [6q25.1/6q25.3]  [t(6;6)(q25;q25)]  
Fusion : MitelmanESR1/USP25 [6q25.1/21q21.1]  [t(6;21)(q25;q21)]  
Fusion : MitelmanTULP4/ESR1 [6q25.3/6q25.1]  [t(6;6)(q25;q25)]  
Fusion PortalESR1 6q25.1 ASPH 8q12.3 BRCA
Fusion PortalESR1 6q25.1 BNC2 9p22.3 BRCA
Fusion PortalESR1 6q25.1 C6orf211 BRCA
Fusion PortalESR1 6q25.1 C6orf97 BRCA
Fusion PortalESR1 6q25.1 MTHFD1L 6q25.1 BRCA
Fusion PortalESR1 6q25.1 TFB1M 6q25.3 LUSC
Fusion PortalESR1 6q25.1 USP25 21q21.1 BRCA
Fusion PortalTULP4 6q25.3 ESR1 6q25.1 LUSC
Fusion : QuiverESR1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerESR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ESR1
dbVarESR1
ClinVarESR1
1000_GenomesESR1 
Exome Variant ServerESR1
ExAC (Exome Aggregation Consortium)ENSG00000091831
GNOMAD BrowserENSG00000091831
Varsome BrowserESR1
Genetic variants : HAPMAP2099
Genomic Variants (DGV)ESR1 [DGVbeta]
DECIPHERESR1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisESR1 
Mutations
ICGC Data PortalESR1 
TCGA Data PortalESR1 
Broad Tumor PortalESR1
OASIS PortalESR1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICESR1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDESR1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ESR1
DgiDB (Drug Gene Interaction Database)ESR1
DoCM (Curated mutations)ESR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ESR1 (select a term)
intoGenESR1
Cancer3DESR1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM114480    133430    157300    608446    615363   
Orphanet8671   
DisGeNETESR1
MedgenESR1
Genetic Testing Registry ESR1
NextProtP03372 [Medical]
TSGene2099
GENETestsESR1
Target ValidationESR1
Huge Navigator ESR1 [HugePedia]
snp3D : Map Gene to Disease2099
BioCentury BCIQESR1
ClinGenESR1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2099
Chemical/Pharm GKB GenePA156
Clinical trialESR1
Miscellaneous
canSAR (ICR)ESR1 (select the gene name)
Probes
Litterature
PubMed499 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineESR1
EVEXESR1
GoPubMedESR1
iHOPESR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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