| Nomenclature |
|---|
| HGNC (Hugo) | ESRRB 3473 |
| Cards |
|---|
| Entrez_Gene (NCBI) | ESRRB estrogen related receptor beta |
| Aliases | DFNB35; ERR; ERR2; ERRb; |
| ERRbeta2; ESRL2; NR3B2 |
| GeneCards (Weizmann) | ESRRB |
| Ensembl hg19 (Hinxton) | ENSG00000119715 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000119715 [Gene_View] ENSG00000119715 [Sequence] chr14:76371347-76501837 [Contig_View] ESRRB [Vega] |
| ICGC DataPortal | ENSG00000119715 |
| TCGA cBioPortal | ESRRB |
| AceView (NCBI) | ESRRB |
| Genatlas (Paris) | ESRRB |
| SOURCE (Princeton) | ESRRB |
| Genetics Home Reference (NIH) | ESRRB |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | ESRRB - chr14:76371347-76501837 + 14q24.3 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | ESRRB - 14q24.3 [Description] (hg19-Feb_2009) |
| GoldenPath | ESRRB - 14q24.3 [CytoView hg19] ESRRB - 14q24.3 [CytoView hg38] |
| ImmunoBase | ENSG00000119715 |
| genome Data Viewer NCBI | ESRRB [Mapview hg19] |
| OMIM | 602167 608565 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AB307714 AK096020 AY451389 AY451390 BC131517 |
| RefSeq transcript (Entrez) | NM_001379180 NM_004452 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | ESRRB |
| Alternative Splicing Gallery | ENSG00000119715 |
| Gene Expression | ESRRB [ NCBI-GEO ] ESRRB [ EBI - ARRAY_EXPRESS ]
ESRRB [ SEEK ] ESRRB [ MEM ] |
| Gene Expression Viewer (FireBrowse) | ESRRB [ Firebrowse - Broad ] |
| Genevisible | Expression of ESRRB in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 2103 |
| GTEX Portal (Tissue expression) | ESRRB |
| Human Protein Atlas | ENSG00000119715-ESRRB [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | O95718 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | O95718 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | O95718 |
| Splice isoforms : SwissVar | O95718 |
| PhosPhoSitePlus | O95718 |
| Domaine pattern : Prosite (Expaxy) | NR_LBD (PS51843) NUCLEAR_REC_DBD_1 (PS00031) NUCLEAR_REC_DBD_2 (PS51030) |
| Domains : Interpro (EBI) | NHR-like_dom_sf Nucl_hrmn_rcpt_lig-bd Nuclear_hrmn_rcpt Oest-rel_rcp Oest_rcpt/oest-rel_rcp Znf_hrmn_rcpt Znf_NHR/GATA |
| Domain families : Pfam (Sanger) | Hormone_recep (PF00104) zf-C4 (PF00105) |
| Domain families : Pfam (NCBI) | pfam00104 pfam00105 |
| Domain families : Smart (EMBL) | HOLI (SM00430) ZnF_C4 (SM00399) |
| Conserved Domain (NCBI) | ESRRB |
| Blocks (Seattle) | ESRRB |
| PDB (RSDB) | 1LO1 |
| PDB Europe | 1LO1 |
| PDB (PDBSum) | 1LO1 |
| PDB (IMB) | 1LO1 |
| Structural Biology KnowledgeBase | 1LO1 |
| SCOP (Structural Classification of Proteins) | 1LO1 |
| CATH (Classification of proteins structures) | 1LO1 |
| Superfamily | O95718 |
| Human Protein Atlas [tissue] | ENSG00000119715-ESRRB [tissue] |
| Peptide Atlas | O95718 |
| HPRD | 03700 |
| IPI | IPI00032812 IPI00965112 IPI00554746 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | O95718 |
| IntAct (EBI) | O95718 |
| BioGRID | ESRRB |
| STRING (EMBL) | ESRRB |
| ZODIAC | ESRRB |
| Ontologies - Pathways |
|---|
| QuickGO | O95718 |
| Ontology : AmiGO | nuclear chromatin condensed chromosome RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific proximal promoter sequence-specific DNA binding RNA polymerase II complex binding DNA-binding transcription activator activity, RNA polymerase II-specific embryonic placenta development DNA-binding transcription factor activity steroid hormone receptor activity nuclear receptor activity steroid binding nucleus nucleoplasm cytoplasm regulation of transcription, DNA-templated transcription initiation from RNA polymerase II promoter transcription factor binding zinc ion binding stem cell division stem cell population maintenance intracellular receptor signaling pathway integrator complex host cell nucleus steroid hormone mediated signaling pathway sequence-specific DNA binding cell dedifferentiation photoreceptor cell maintenance positive regulation of glycogen biosynthetic process positive regulation of glycolytic process positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II inner ear development repressing transcription factor binding positive regulation of transcription involved in G1/S transition of mitotic cell cycle positive regulation of transcription involved in G2/M transition of mitotic cell cycle positive regulation of stem cell population maintenance regulation of stem cell division negative regulation of stem cell differentiation |
| Ontology : EGO-EBI | nuclear chromatin condensed chromosome RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific proximal promoter sequence-specific DNA binding RNA polymerase II complex binding DNA-binding transcription activator activity, RNA polymerase II-specific embryonic placenta development DNA-binding transcription factor activity steroid hormone receptor activity nuclear receptor activity steroid binding nucleus nucleoplasm cytoplasm regulation of transcription, DNA-templated transcription initiation from RNA polymerase II promoter transcription factor binding zinc ion binding stem cell division stem cell population maintenance intracellular receptor signaling pathway integrator complex host cell nucleus steroid hormone mediated signaling pathway sequence-specific DNA binding cell dedifferentiation photoreceptor cell maintenance positive regulation of glycogen biosynthetic process positive regulation of glycolytic process positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II inner ear development repressing transcription factor binding positive regulation of transcription involved in G1/S transition of mitotic cell cycle positive regulation of transcription involved in G2/M transition of mitotic cell cycle positive regulation of stem cell population maintenance regulation of stem cell division negative regulation of stem cell differentiation |
| NDEx Network | ESRRB |
| Atlas of Cancer Signalling Network | ESRRB |
| Wikipedia pathways | ESRRB |
| Orthology - Evolution |
|---|
| OrthoDB | 2103 |
| GeneTree (enSembl) | ENSG00000119715 |
| Phylogenetic Trees/Animal Genes : TreeFam | ESRRB |
| HOGENOM | O95718 |
| Homologs : HomoloGene | ESRRB |
| Homology/Alignments : Family Browser (UCSC) | ESRRB |
| Gene fusions - Rearrangements |
|---|
| Fusion : Mitelman | PARVA/ESRRB [11p15.3/14q24.3] |
| Fusion Portal | PARVA 11p15.3 ESRRB 14q24.3 PRAD |
| Fusion : Quiver | ESRRB |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | ESRRB [hg38] |
| dbVar | ESRRB |
| ClinVar | ESRRB |
| Monarch | ESRRB |
| 1000_Genomes | ESRRB |
| Exome Variant Server | ESRRB |
| GNOMAD Browser | ENSG00000119715 |
| Varsome Browser | ESRRB |
| Genomic Variants (DGV) | ESRRB [DGVbeta] |
| DECIPHER | ESRRB [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | ESRRB |
| Mutations |
|---|
| ICGC Data Portal | ESRRB |
| TCGA Data Portal | ESRRB |
| Broad Tumor Portal | ESRRB |
| OASIS Portal | ESRRB [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | ESRRB [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | ESRRB |
| Mutations and Diseases : HGMD | ESRRB |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| LOVD (Leiden Open Variation Database) | MSeqDR-LSDB Mitochondrial Disease Locus Specific Database |
| BioMuta | search ESRRB |
| DgiDB (Drug Gene Interaction Database) | ESRRB |
| DoCM (Curated mutations) | ESRRB (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | ESRRB (select a term) |
| intoGen | ESRRB |
| Cancer3D | ESRRB(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 602167 608565 |
| Orphanet | 12047 |
| DisGeNET | ESRRB |
| Medgen | ESRRB |
| Genetic Testing Registry | ESRRB
|
| NextProt | O95718 [Medical] |
| GENETests | ESRRB |
| Target Validation | ESRRB |
| Huge Navigator |
ESRRB [HugePedia] |
| ClinGen | ESRRB |
| Clinical trials, drugs, therapy |
|---|
| MyCancerGenome | ESRRB |
| Protein Interactions : CTD | |
| Pharm GKB Gene | PA27889 |
| Pharos | O95718 |
| Clinical trial | ESRRB |
| Miscellaneous |
|---|
| canSAR (ICR) | ESRRB (select the gene name) |
| Harmonizome | ESRRB |
| DataMed Index | ESRRB |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 55 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| EVEX | ESRRB |
