| Nomenclature |
|---|
| HGNC (Hugo) | ESRRB 3473 |
| Cards |
|---|
| Entrez_Gene (NCBI) | ESRRB 2103 estrogen related receptor beta |
| Aliases | DFNB35; ERR2; ERRb; ESRL2; |
| NR3B2 |
| GeneCards (Weizmann) | ESRRB |
| Ensembl hg19 (Hinxton) | ENSG00000119715 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000119715 [Gene_View] chr14:76371347-76501837 [Contig_View] ESRRB [Vega] |
| ICGC DataPortal | ENSG00000119715 |
| TCGA cBioPortal | ESRRB |
| AceView (NCBI) | ESRRB |
| Genatlas (Paris) | ESRRB |
| WikiGenes | 2103 |
| SOURCE (Princeton) | ESRRB |
| Genetics Home Reference (NIH) | ESRRB |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | ESRRB - chr14:76371347-76501837 + 14q24.3 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | ESRRB - 14q24.3 [Description] (hg19-Feb_2009) |
| Ensembl | ESRRB - 14q24.3 [CytoView hg19] ESRRB - 14q24.3 [CytoView hg38] |
| Mapping of homologs : NCBI | ESRRB [Mapview hg19] ESRRB [Mapview hg38] |
| OMIM | 602167 608565 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AB307714 AK096020 AY451389 AY451390 BC131517 |
| RefSeq transcript (Entrez) | NM_004452 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | ESRRB |
| Cluster EST : Unigene | Hs.435845 [ NCBI ] |
| CGAP (NCI) | Hs.435845 |
| Alternative Splicing Gallery | ENSG00000119715 |
| Gene Expression | ESRRB [ NCBI-GEO ] ESRRB [ EBI - ARRAY_EXPRESS ]
ESRRB [ SEEK ] ESRRB [ MEM ] |
| Gene Expression Viewer (FireBrowse) | ESRRB [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 2103 |
| GTEX Portal (Tissue expression) | ESRRB |
| Human Protein Atlas | ENSG00000119715-ESRRB [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | O95718 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | O95718 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | O95718 |
| Splice isoforms : SwissVar | O95718 |
| PhosPhoSitePlus | O95718 |
| Domaine pattern : Prosite (Expaxy) | NUCLEAR_REC_DBD_1 (PS00031) NUCLEAR_REC_DBD_2 (PS51030) |
| Domains : Interpro (EBI) | Nucl_hrmn_rcpt_lig-bd Nuclear_hrmn_rcpt Oest-rel_rcp Oest_rcpt/oest-rel_rcp Znf_hrmn_rcpt Znf_NHR/GATA |
| Domain families : Pfam (Sanger) | Hormone_recep (PF00104) zf-C4 (PF00105) |
| Domain families : Pfam (NCBI) | pfam00104 pfam00105 |
| Domain families : Smart (EMBL) | HOLI (SM00430) ZnF_C4 (SM00399) |
| Conserved Domain (NCBI) | ESRRB |
| DMDM Disease mutations | 2103 |
| Blocks (Seattle) | ESRRB |
| PDB (SRS) | 1LO1 |
| PDB (PDBSum) | 1LO1 |
| PDB (IMB) | 1LO1 |
| PDB (RSDB) | 1LO1 |
| Structural Biology KnowledgeBase | 1LO1 |
| SCOP (Structural Classification of Proteins) | 1LO1 |
| CATH (Classification of proteins structures) | 1LO1 |
| Superfamily | O95718 |
| Human Protein Atlas [tissue] | ENSG00000119715-ESRRB [tissue] |
| Peptide Atlas | O95718 |
| HPRD | 03700 |
| IPI | IPI00032812 IPI00965112 IPI00554746 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | O95718 |
| IntAct (EBI) | O95718 |
| FunCoup | ENSG00000119715 |
| BioGRID | ESRRB |
| STRING (EMBL) | ESRRB |
| ZODIAC | ESRRB |
| Ontologies - Pathways |
|---|
| QuickGO | O95718 |
| Ontology : AmiGO | condensed chromosome RNA polymerase II distal enhancer sequence-specific DNA binding RNA polymerase II core binding core promoter binding enhancer sequence-specific DNA binding transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding embryonic placenta development DNA binding transcription factor activity transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding steroid hormone receptor activity transcription coactivator activity nuclear receptor activity steroid binding nucleus nucleoplasm cytoplasm regulation of transcription, DNA-templated transcription initiation from RNA polymerase II promoter transcription factor binding zinc ion binding stem cell division stem cell population maintenance intracellular receptor signaling pathway integrator complex enhancer binding steroid hormone mediated signaling pathway sequence-specific DNA binding cell dedifferentiation photoreceptor cell maintenance positive regulation of glycogen biosynthetic process positive regulation of glycolytic process positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II inner ear development positive regulation of transcription involved in G1/S transition of mitotic cell cycle positive regulation of transcription involved in G2/M transition of mitotic cell cycle positive regulation of stem cell population maintenance regulation of stem cell division negative regulation of stem cell differentiation |
| Ontology : EGO-EBI | condensed chromosome RNA polymerase II distal enhancer sequence-specific DNA binding RNA polymerase II core binding core promoter binding enhancer sequence-specific DNA binding transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding embryonic placenta development DNA binding transcription factor activity transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding steroid hormone receptor activity transcription coactivator activity nuclear receptor activity steroid binding nucleus nucleoplasm cytoplasm regulation of transcription, DNA-templated transcription initiation from RNA polymerase II promoter transcription factor binding zinc ion binding stem cell division stem cell population maintenance intracellular receptor signaling pathway integrator complex enhancer binding steroid hormone mediated signaling pathway sequence-specific DNA binding cell dedifferentiation photoreceptor cell maintenance positive regulation of glycogen biosynthetic process positive regulation of glycolytic process positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II inner ear development positive regulation of transcription involved in G1/S transition of mitotic cell cycle positive regulation of transcription involved in G2/M transition of mitotic cell cycle positive regulation of stem cell population maintenance regulation of stem cell division negative regulation of stem cell differentiation |
| NDEx Network | ESRRB |
| Atlas of Cancer Signalling Network | ESRRB |
| Wikipedia pathways | ESRRB |
| Orthology - Evolution |
|---|
| OrthoDB | 2103 |
| GeneTree (enSembl) | ENSG00000119715 |
| Phylogenetic Trees/Animal Genes : TreeFam | ESRRB |
| HOVERGEN | O95718 |
| HOGENOM | O95718 |
| Homologs : HomoloGene | ESRRB |
| Homology/Alignments : Family Browser (UCSC) | ESRRB |
| Gene fusions - Rearrangements |
|---|
| Fusion : Mitelman | PARVA/ESRRB [11p15.3/14q24.3] [t(11;14)(p15;q24)] |
| Fusion: TCGA_MDACC | PARVA 11p15.3 ESRRB 14q24.3 PRAD |
| Fusion Portal | PARVA 11p15.3 ESRRB 14q24.3 PRAD |
| Fusion : Quiver | ESRRB |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | ESRRB [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | ESRRB |
| dbVar | ESRRB |
| ClinVar | ESRRB |
| 1000_Genomes | ESRRB |
| Exome Variant Server | ESRRB |
| ExAC (Exome Aggregation Consortium) | ENSG00000119715 |
| GNOMAD Browser | ENSG00000119715 |
| Genetic variants : HAPMAP | 2103 |
| Genomic Variants (DGV) | ESRRB [DGVbeta] |
| DECIPHER | ESRRB [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | ESRRB |
| Mutations |
|---|
| ICGC Data Portal | ESRRB |
| TCGA Data Portal | ESRRB |
| Broad Tumor Portal | ESRRB |
| OASIS Portal | ESRRB [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | ESRRB [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | ESRRB |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| LOVD (Leiden Open Variation Database) | MSeqDR-LSDB Mitochondrial Disease Locus Specific Database |
| BioMuta | search ESRRB |
| DgiDB (Drug Gene Interaction Database) | ESRRB |
| DoCM (Curated mutations) | ESRRB (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | ESRRB (select a term) |
| intoGen | ESRRB |
| Cancer3D | ESRRB(select the gene name) |
| Impact of mutations | [PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 602167 608565 |
| Orphanet | 12047 |
| DisGeNET | ESRRB |
| Medgen | ESRRB |
| Genetic Testing Registry | ESRRB
|
| NextProt | O95718 [Medical] |
| TSGene | 2103 |
| GENETests | ESRRB |
| Target Validation | ESRRB |
| Huge Navigator |
ESRRB [HugePedia] |
| snp3D : Map Gene to Disease | 2103 |
| BioCentury BCIQ | ESRRB |
| ClinGen | ESRRB |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 2103 |
| Chemical/Pharm GKB Gene | PA27889 |
| Clinical trial | ESRRB |
| Miscellaneous |
|---|
| canSAR (ICR) | ESRRB (select the gene name) |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 44 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | ESRRB |
| EVEX | ESRRB |
| GoPubMed | ESRRB |
| iHOP | ESRRB |
