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ETV2 (ETS variant 2)

Identity

Alias_namesets variant gene 2
Alias_symbol (synonym)ER71
Other aliasETSRP71
HGNC (Hugo) ETV2
LocusID (NCBI) 2116
Atlas_Id 46798
Location 19q13.12  [Link to chromosome band 19q13]
Location_base_pair Starts at 35641737 and ends at 35644871 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ETV2   3491
Cards
Entrez_Gene (NCBI)ETV2  2116  ETS variant 2
AliasesER71; ETSRP71
GeneCards (Weizmann)ETV2
Ensembl hg19 (Hinxton)ENSG00000105672 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105672 [Gene_View]  chr19:35641737-35644871 [Contig_View]  ETV2 [Vega]
ICGC DataPortalENSG00000105672
TCGA cBioPortalETV2
AceView (NCBI)ETV2
Genatlas (Paris)ETV2
WikiGenes2116
SOURCE (Princeton)ETV2
Genetics Home Reference (NIH)ETV2
Genomic and cartography
GoldenPath hg38 (UCSC)ETV2  -     chr19:35641737-35644871 +  19q13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ETV2  -     19q13.12   [Description]    (hg19-Feb_2009)
EnsemblETV2 - 19q13.12 [CytoView hg19]  ETV2 - 19q13.12 [CytoView hg38]
Mapping of homologs : NCBIETV2 [Mapview hg19]  ETV2 [Mapview hg38]
OMIM609358   
Gene and transcription
Genbank (Entrez)AA885210 AF000671 AK097439 BC040908 BC107123
RefSeq transcript (Entrez)NM_001300974 NM_001304549 NM_014209
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ETV2
Cluster EST : UnigeneHs.194061 [ NCBI ]
CGAP (NCI)Hs.194061
Alternative Splicing GalleryENSG00000105672
Gene ExpressionETV2 [ NCBI-GEO ]   ETV2 [ EBI - ARRAY_EXPRESS ]   ETV2 [ SEEK ]   ETV2 [ MEM ]
Gene Expression Viewer (FireBrowse)ETV2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2116
GTEX Portal (Tissue expression)ETV2
Human Protein AtlasENSG00000105672-ETV2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00321   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00321  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00321
Splice isoforms : SwissVarO00321
PhosPhoSitePlusO00321
Domaine pattern : Prosite (Expaxy)ETS_DOMAIN_1 (PS00345)    ETS_DOMAIN_2 (PS00346)    ETS_DOMAIN_3 (PS50061)   
Domains : Interpro (EBI)Ets_dom    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)Ets (PF00178)   
Domain families : Pfam (NCBI)pfam00178   
Domain families : Smart (EMBL)ETS (SM00413)  
Conserved Domain (NCBI)ETV2
DMDM Disease mutations2116
Blocks (Seattle)ETV2
SuperfamilyO00321
Human Protein Atlas [tissue]ENSG00000105672-ETV2 [tissue]
Peptide AtlasO00321
HPRD16871
IPIIPI00654648   IPI00654570   IPI00743432   IPI00893164   
Protein Interaction databases
DIP (DOE-UCLA)O00321
IntAct (EBI)O00321
FunCoupENSG00000105672
BioGRIDETV2
STRING (EMBL)ETV2
ZODIACETV2
Ontologies - Pathways
QuickGOO00321
Ontology : AmiGORNA polymerase II core promoter proximal region sequence-specific DNA binding  RNA polymerase II transcription factor activity, sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  blastocyst development  placenta development  nucleus  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  Notch signaling pathway  Wnt signaling pathway  cell differentiation  erythrocyte differentiation  positive regulation of endothelial cell differentiation  positive regulation of transcription from RNA polymerase II promoter  blood vessel morphogenesis  BMP signaling pathway involved in mesodermal cell fate specification  positive regulation of mesoderm development  
Ontology : EGO-EBIRNA polymerase II core promoter proximal region sequence-specific DNA binding  RNA polymerase II transcription factor activity, sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  blastocyst development  placenta development  nucleus  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  Notch signaling pathway  Wnt signaling pathway  cell differentiation  erythrocyte differentiation  positive regulation of endothelial cell differentiation  positive regulation of transcription from RNA polymerase II promoter  blood vessel morphogenesis  BMP signaling pathway involved in mesodermal cell fate specification  positive regulation of mesoderm development  
NDEx NetworkETV2
Atlas of Cancer Signalling NetworkETV2
Wikipedia pathwaysETV2
Orthology - Evolution
OrthoDB2116
GeneTree (enSembl)ENSG00000105672
Phylogenetic Trees/Animal Genes : TreeFamETV2
HOVERGENO00321
HOGENOMO00321
Homologs : HomoloGeneETV2
Homology/Alignments : Family Browser (UCSC)ETV2
Gene fusions - Rearrangements
Tumor Fusion PortalETV2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerETV2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ETV2
dbVarETV2
ClinVarETV2
1000_GenomesETV2 
Exome Variant ServerETV2
ExAC (Exome Aggregation Consortium)ENSG00000105672
GNOMAD BrowserENSG00000105672
Genetic variants : HAPMAP2116
Genomic Variants (DGV)ETV2 [DGVbeta]
DECIPHERETV2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisETV2 
Mutations
ICGC Data PortalETV2 
TCGA Data PortalETV2 
Broad Tumor PortalETV2
OASIS PortalETV2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICETV2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDETV2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ETV2
DgiDB (Drug Gene Interaction Database)ETV2
DoCM (Curated mutations)ETV2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ETV2 (select a term)
intoGenETV2
Cancer3DETV2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609358   
Orphanet
DisGeNETETV2
MedgenETV2
Genetic Testing Registry ETV2
NextProtO00321 [Medical]
TSGene2116
GENETestsETV2
Target ValidationETV2
Huge Navigator ETV2 [HugePedia]
snp3D : Map Gene to Disease2116
BioCentury BCIQETV2
ClinGenETV2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2116
Chemical/Pharm GKB GenePA27905
Clinical trialETV2
Miscellaneous
canSAR (ICR)ETV2 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineETV2
EVEXETV2
GoPubMedETV2
iHOPETV2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:12:23 CET 2017

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