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ETV2 (ETS variant transcription factor 2)

Identity

Alias (NCBI)ER71
ETSRP71
HGNC (Hugo) ETV2
HGNC Alias symbER71
HGNC Previous nameets variant gene 2
 ETS variant 2
LocusID (NCBI) 2116
Atlas_Id 46798
Location 19q13.12  [Link to chromosome band 19q13]
Location_base_pair Starts at 35641745 and ends at 35644871 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ETV2   3491
Cards
Entrez_Gene (NCBI)ETV2    ETS variant transcription factor 2
AliasesER71; ETSRP71
GeneCards (Weizmann)ETV2
Ensembl hg19 (Hinxton)ENSG00000105672 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105672 [Gene_View]  ENSG00000105672 [Sequence]  chr19:35641745-35644871 [Contig_View]  ETV2 [Vega]
ICGC DataPortalENSG00000105672
TCGA cBioPortalETV2
AceView (NCBI)ETV2
Genatlas (Paris)ETV2
SOURCE (Princeton)ETV2
Genetics Home Reference (NIH)ETV2
Genomic and cartography
GoldenPath hg38 (UCSC)ETV2  -     chr19:35641745-35644871 +  19q13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ETV2  -     19q13.12   [Description]    (hg19-Feb_2009)
GoldenPathETV2 - 19q13.12 [CytoView hg19]  ETV2 - 19q13.12 [CytoView hg38]
ImmunoBaseENSG00000105672
Genome Data Viewer NCBIETV2 [Mapview hg19]  
OMIM609358   
Gene and transcription
Genbank (Entrez)AA885210 AF000671 AK097439 BC040908 BC107123
RefSeq transcript (Entrez)NM_001300974 NM_001304549 NM_014209
Consensus coding sequences : CCDS (NCBI)ETV2
Gene ExpressionETV2 [ NCBI-GEO ]   ETV2 [ EBI - ARRAY_EXPRESS ]   ETV2 [ SEEK ]   ETV2 [ MEM ]
Gene Expression Viewer (FireBrowse)ETV2 [ Firebrowse - Broad ]
GenevisibleExpression of ETV2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2116
GTEX Portal (Tissue expression)ETV2
Human Protein AtlasENSG00000105672-ETV2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00321   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00321  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00321
PhosPhoSitePlusO00321
Domaine pattern : Prosite (Expaxy)ETS_DOMAIN_1 (PS00345)    ETS_DOMAIN_2 (PS00346)    ETS_DOMAIN_3 (PS50061)   
Domains : Interpro (EBI)Ets_dom    WH-like_DNA-bd_sf    WH_DNA-bd_sf   
Domain families : Pfam (Sanger)Ets (PF00178)   
Domain families : Pfam (NCBI)pfam00178   
Domain families : Smart (EMBL)ETS (SM00413)  
Conserved Domain (NCBI)ETV2
SuperfamilyO00321
AlphaFold pdb e-kbO00321   
Human Protein Atlas [tissue]ENSG00000105672-ETV2 [tissue]
HPRD16871
Protein Interaction databases
DIP (DOE-UCLA)O00321
IntAct (EBI)O00321
BioGRIDETV2
STRING (EMBL)ETV2
ZODIACETV2
Ontologies - Pathways
QuickGOO00321
Ontology : AmiGORNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  blastocyst development  placenta development  nucleus  regulation of transcription by RNA polymerase II  Notch signaling pathway  positive regulation of gene expression  Wnt signaling pathway  cell differentiation  erythrocyte differentiation  positive regulation of endothelial cell differentiation  positive regulation of transcription by RNA polymerase II  blood vessel morphogenesis  BMP signaling pathway involved in mesodermal cell fate specification  sequence-specific double-stranded DNA binding  positive regulation of mesoderm development  
Ontology : EGO-EBIRNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  blastocyst development  placenta development  nucleus  regulation of transcription by RNA polymerase II  Notch signaling pathway  positive regulation of gene expression  Wnt signaling pathway  cell differentiation  erythrocyte differentiation  positive regulation of endothelial cell differentiation  positive regulation of transcription by RNA polymerase II  blood vessel morphogenesis  BMP signaling pathway involved in mesodermal cell fate specification  sequence-specific double-stranded DNA binding  positive regulation of mesoderm development  
NDEx NetworkETV2
Atlas of Cancer Signalling NetworkETV2
Wikipedia pathwaysETV2
Orthology - Evolution
OrthoDB2116
GeneTree (enSembl)ENSG00000105672
Phylogenetic Trees/Animal Genes : TreeFamETV2
Homologs : HomoloGeneETV2
Homology/Alignments : Family Browser (UCSC)ETV2
Gene fusions - Rearrangements
Fusion : QuiverETV2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerETV2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ETV2
dbVarETV2
ClinVarETV2
MonarchETV2
1000_GenomesETV2 
Exome Variant ServerETV2
GNOMAD BrowserENSG00000105672
Varsome BrowserETV2
ACMGETV2 variants
VarityO00321
Genomic Variants (DGV)ETV2 [DGVbeta]
DECIPHERETV2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisETV2 
Mutations
ICGC Data PortalETV2 
TCGA Data PortalETV2 
Broad Tumor PortalETV2
OASIS PortalETV2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICETV2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DETV2
Mutations and Diseases : HGMDETV2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaETV2
DgiDB (Drug Gene Interaction Database)ETV2
DoCM (Curated mutations)ETV2
CIViC (Clinical Interpretations of Variants in Cancer)ETV2
Cancer3DETV2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609358   
Orphanet
DisGeNETETV2
MedgenETV2
Genetic Testing Registry ETV2
NextProtO00321 [Medical]
GENETestsETV2
Target ValidationETV2
Huge Navigator ETV2 [HugePedia]
ClinGenETV2
Clinical trials, drugs, therapy
MyCancerGenomeETV2
Protein Interactions : CTDETV2
Pharm GKB GenePA27905
PharosO00321
Clinical trialETV2
Miscellaneous
canSAR (ICR)ETV2
HarmonizomeETV2
ARCHS4ETV2
DataMed IndexETV2
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXETV2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 20 12:32:35 CET 2022

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