ETV5 (ETS variant transcription factor 5)

2003-02-01  

Identity

HGNC
LOCATION
3q27.2
LOCUSID
ALIAS
ERM
FUSION GENES

Other Information

Locus ID:

NCBI: 2119
MIM: 601600
HGNC: 3494
Ensembl: ENSG00000244405

Variants:

dbSNP: 2119
ClinVar: 2119
TCGA: ENSG00000244405
COSMIC: ETV5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000244405ENST00000306376P41161
ENSG00000244405ENST00000413301C9J5A5
ENSG00000244405ENST00000421809C9J0Z2
ENSG00000244405ENST00000422039C9JR66
ENSG00000244405ENST00000433149H7C1D2
ENSG00000244405ENST00000434744P41161
ENSG00000244405ENST00000440773C9JMF0

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
Transcriptional misregulation in cancerKEGGko05202
Transcriptional misregulation in cancerKEGGhsa05202

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
181722982008Characterization of TMPRSS2:ETV5 and SLC45A3:ETV5 gene fusions in prostate cancer.101
224255842012ETV1, 4 and 5: an oncogenic subfamily of ETS transcription factors.94
196924902009Obesity genes identified in genome-wide association studies are associated with adiposity measures and potentially with nutrient-specific food preference.77
198121712010Cumulative effects and predictive value of common obesity-susceptibility variants identified by genome-wide association studies.74
205208482010Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth.70
123877352002ITAM-based interaction of ERM proteins with Syk mediates signaling by the leukocyte adhesion receptor PSGL-1.64
207245812010Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide association studies.47
202153972010Implication of genetic variants near NEGR1, SEC16B, TMEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, and KCTD15 with obesity and type 2 diabetes in 7705 Chinese.44
166159182006Structural basis for NHERF recognition by ERM proteins.43
208161952010Analyses of shared genetic factors between asthma and obesity in children.43

Citation

Dessen P

ETV5 (ETS variant transcription factor 5)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40505/etv5