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EVI5 (ecotropic viral integration site 5)

Identity

Alias (NCBI)EVI-5
NB4S
HGNC (Hugo) EVI5
HGNC Alias symbNB4S
HGNC Alias nameneuroblastoma stage 4S gene
LocusID (NCBI) 7813
Atlas_Id 40511
Location 1p22.1  [Link to chromosome band 1p22]
Location_base_pair Starts at 92508696 and ends at 92792410 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
C1RL (12p13.31) / EVI5 (1p22.1)C20orf194 (20p13) / EVI5 (1p22.1)EVI5 (1p22.1) / PEAK1 (15q24.3)
EVI5 (1p22.1) / RFWD2 (1q25.1)EVI5 (1p22.1) / TMEM26 (10q21.2)EVI5 (1p22.1) / TMEM87A (15q15.1)
KCNQ3 (8q24.22) / EVI5 (1p22.1)MED18 (1p35.3) / EVI5 (1p22.1)C20orf194 20p13 / EVI5 1p22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)EVI5   3501
Cards
Entrez_Gene (NCBI)EVI5    ecotropic viral integration site 5
AliasesEVI-5; NB4S
GeneCards (Weizmann)EVI5
Ensembl hg19 (Hinxton)ENSG00000067208 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000067208 [Gene_View]  ENSG00000067208 [Sequence]  chr1:92508696-92792410 [Contig_View]  EVI5 [Vega]
ICGC DataPortalENSG00000067208
TCGA cBioPortalEVI5
AceView (NCBI)EVI5
Genatlas (Paris)EVI5
SOURCE (Princeton)EVI5
Genetics Home Reference (NIH)EVI5
Genomic and cartography
GoldenPath hg38 (UCSC)EVI5  -     chr1:92508696-92792410 -  1p22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EVI5  -     1p22.1   [Description]    (hg19-Feb_2009)
GoldenPathEVI5 - 1p22.1 [CytoView hg19]  EVI5 - 1p22.1 [CytoView hg38]
ImmunoBaseENSG00000067208
Genome Data Viewer NCBIEVI5 [Mapview hg19]  
OMIM602942   
Gene and transcription
Genbank (Entrez)AA725529 AB209513 AB449875 AF008915 BM835541
RefSeq transcript (Entrez)NM_001308248 NM_001350197 NM_001350198 NM_001377210 NM_001377211 NM_001377212 NM_001377213 NM_005665
Consensus coding sequences : CCDS (NCBI)EVI5
Gene ExpressionEVI5 [ NCBI-GEO ]   EVI5 [ EBI - ARRAY_EXPRESS ]   EVI5 [ SEEK ]   EVI5 [ MEM ]
Gene Expression Viewer (FireBrowse)EVI5 [ Firebrowse - Broad ]
GenevisibleExpression of EVI5 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7813
GTEX Portal (Tissue expression)EVI5
Human Protein AtlasENSG00000067208-EVI5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60447   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60447  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60447
PhosPhoSitePlusO60447
Domaine pattern : Prosite (Expaxy)TBC_RABGAP (PS50086)   
Domains : Interpro (EBI)Evi5    Rab-GTPase-TBC_dom    Rab-GTPase_TBC_sf   
Domain families : Pfam (Sanger)RabGAP-TBC (PF00566)   
Domain families : Pfam (NCBI)pfam00566   
Domain families : Smart (EMBL)TBC (SM00164)  
Conserved Domain (NCBI)EVI5
SuperfamilyO60447
AlphaFold pdb e-kbO60447   
Human Protein Atlas [tissue]ENSG00000067208-EVI5 [tissue]
HPRD04249
Protein Interaction databases
DIP (DOE-UCLA)O60447
IntAct (EBI)O60447
BioGRIDEVI5
STRING (EMBL)EVI5
ZODIACEVI5
Ontologies - Pathways
QuickGOO60447
Ontology : AmiGOGTPase activator activity  GTPase activator activity  protein binding  nucleus  microtubule organizing center  spindle  cytosol  intracellular protein transport  cell cycle  small GTPase binding  retrograde transport, endosome to Golgi  positive regulation of GTPase activity  cell division  activation of GTPase activity  regulation of cilium assembly  
Ontology : EGO-EBIGTPase activator activity  GTPase activator activity  protein binding  nucleus  microtubule organizing center  spindle  cytosol  intracellular protein transport  cell cycle  small GTPase binding  retrograde transport, endosome to Golgi  positive regulation of GTPase activity  cell division  activation of GTPase activity  regulation of cilium assembly  
NDEx NetworkEVI5
Atlas of Cancer Signalling NetworkEVI5
Wikipedia pathwaysEVI5
Orthology - Evolution
OrthoDB7813
GeneTree (enSembl)ENSG00000067208
Phylogenetic Trees/Animal Genes : TreeFamEVI5
Homologs : HomoloGeneEVI5
Homology/Alignments : Family Browser (UCSC)EVI5
Gene fusions - Rearrangements
Fusion : MitelmanC20orf194/EVI5 [20p13/1p22.1]  
Fusion : QuiverEVI5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEVI5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EVI5
dbVarEVI5
ClinVarEVI5
MonarchEVI5
1000_GenomesEVI5 
Exome Variant ServerEVI5
GNOMAD BrowserENSG00000067208
Varsome BrowserEVI5
ACMGEVI5 variants
VarityO60447
Genomic Variants (DGV)EVI5 [DGVbeta]
DECIPHEREVI5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEVI5 
Mutations
ICGC Data PortalEVI5 
TCGA Data PortalEVI5 
Broad Tumor PortalEVI5
OASIS PortalEVI5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEVI5  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DEVI5
Mutations and Diseases : HGMDEVI5
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaEVI5
DgiDB (Drug Gene Interaction Database)EVI5
DoCM (Curated mutations)EVI5
CIViC (Clinical Interpretations of Variants in Cancer)EVI5
Cancer3DEVI5
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602942   
Orphanet
DisGeNETEVI5
MedgenEVI5
Genetic Testing Registry EVI5
NextProtO60447 [Medical]
GENETestsEVI5
Target ValidationEVI5
Huge Navigator EVI5 [HugePedia]
ClinGenEVI5
Clinical trials, drugs, therapy
MyCancerGenomeEVI5
Protein Interactions : CTDEVI5
Pharm GKB GenePA27915
PharosO60447
Clinical trialEVI5
Miscellaneous
canSAR (ICR)EVI5
HarmonizomeEVI5
DataMed IndexEVI5
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXEVI5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:08:35 CEST 2021

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