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EVL (Enah/Vasp-like)

Identity

Alias_symbol (synonym)RNB6
Other alias
HGNC (Hugo) EVL
LocusID (NCBI) 51466
Atlas_Id 50152
Location 14q32.2  [Link to chromosome band 14q32]
Location_base_pair Starts at 100531751 and ends at 100610573 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
AMBRA1 (11p11.2) / EVL (14q32.2)ARMC9 (2q37.1) / EVL (14q32.2)CLMN (14q32.13) / EVL (14q32.2)
CPSF7 (11q12.2) / EVL (14q32.2)EVL (14q32.2) / EML1 (14q32.2)EVL (14q32.2) / HKR1 (19q13.12)
EVL (14q32.2) / HNRNPA2B1 (7p15.2)LOC100507412 (-) / EVL (14q32.2)RCOR1 (14q32.31) / EVL (14q32.2)
ZNF79 (9q33.3) / EVL (14q32.2)ARMC9 2q37.1 / EVL 14q32.2CLMN 14q32.13 / EVL 14q32.2
EVL 14q32.2 / EML1 14q32.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EVL   20234
Cards
Entrez_Gene (NCBI)EVL  51466  Enah/Vasp-like
AliasesRNB6
GeneCards (Weizmann)EVL
Ensembl hg19 (Hinxton)ENSG00000196405 [Gene_View]  chr14:100531751-100610573 [Contig_View]  EVL [Vega]
Ensembl hg38 (Hinxton)ENSG00000196405 [Gene_View]  chr14:100531751-100610573 [Contig_View]  EVL [Vega]
ICGC DataPortalENSG00000196405
TCGA cBioPortalEVL
AceView (NCBI)EVL
Genatlas (Paris)EVL
WikiGenes51466
SOURCE (Princeton)EVL
Genetics Home Reference (NIH)EVL
Genomic and cartography
GoldenPath hg19 (UCSC)EVL  -     chr14:100531751-100610573 +  14q32.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)EVL  -     14q32.2   [Description]    (hg38-Dec_2013)
EnsemblEVL - 14q32.2 [CytoView hg19]  EVL - 14q32.2 [CytoView hg38]
Mapping of homologs : NCBIEVL [Mapview hg19]  EVL [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF052504 AF087843 AF112209 AF131766 AK091634
RefSeq transcript (Entrez)NM_016337
RefSeq genomic (Entrez)NC_000014 NC_018925 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)EVL
Cluster EST : UnigeneHs.125867 [ NCBI ]
CGAP (NCI)Hs.125867
Alternative Splicing GalleryENSG00000196405
Gene ExpressionEVL [ NCBI-GEO ]   EVL [ EBI - ARRAY_EXPRESS ]   EVL [ SEEK ]   EVL [ MEM ]
Gene Expression Viewer (FireBrowse)EVL [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51466
GTEX Portal (Tissue expression)EVL
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UI08   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UI08  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UI08
Splice isoforms : SwissVarQ9UI08
PhosPhoSitePlusQ9UI08
Domaine pattern : Prosite (Expaxy)WH1 (PS50229)   
Domains : Interpro (EBI)PH_dom-like    Vasodilator_phosphoprotein    VASP_tetra    WH1/EVH1_dom   
Domain families : Pfam (Sanger)VASP_tetra (PF08776)    WH1 (PF00568)   
Domain families : Pfam (NCBI)pfam08776    pfam00568   
Domain families : Smart (EMBL)WH1 (SM00461)  
Conserved Domain (NCBI)EVL
DMDM Disease mutations51466
Blocks (Seattle)EVL
SuperfamilyQ9UI08
Human Protein AtlasENSG00000196405
Peptide AtlasQ9UI08
HPRD10942
IPIIPI00170979   IPI00218245   IPI00922599   IPI01012365   IPI01026542   IPI01026049   IPI01026235   IPI01026343   IPI01026413   IPI01024722   IPI01024862   
Protein Interaction databases
DIP (DOE-UCLA)Q9UI08
IntAct (EBI)Q9UI08
FunCoupENSG00000196405
BioGRIDEVL
STRING (EMBL)EVL
ZODIACEVL
Ontologies - Pathways
QuickGOQ9UI08
Ontology : AmiGOactin binding  protein binding  profilin binding  cytoplasm  cytosol  cytoskeleton  focal adhesion  actin filament organization  cell surface receptor signaling pathway  nervous system development  axon guidance  actin polymerization or depolymerization  organ morphogenesis  negative regulation of epithelial cell migration  membrane  SH3 domain binding  lamellipodium  positive regulation of actin filament polymerization  protein homotetramerization  positive regulation of stress fiber assembly  negative regulation of ruffle assembly  
Ontology : EGO-EBIactin binding  protein binding  profilin binding  cytoplasm  cytosol  cytoskeleton  focal adhesion  actin filament organization  cell surface receptor signaling pathway  nervous system development  axon guidance  actin polymerization or depolymerization  organ morphogenesis  negative regulation of epithelial cell migration  membrane  SH3 domain binding  lamellipodium  positive regulation of actin filament polymerization  protein homotetramerization  positive regulation of stress fiber assembly  negative regulation of ruffle assembly  
NDEx NetworkEVL
Atlas of Cancer Signalling NetworkEVL
Wikipedia pathwaysEVL
Orthology - Evolution
OrthoDB51466
GeneTree (enSembl)ENSG00000196405
Phylogenetic Trees/Animal Genes : TreeFamEVL
HOVERGENQ9UI08
HOGENOMQ9UI08
Homologs : HomoloGeneEVL
Homology/Alignments : Family Browser (UCSC)EVL
Gene fusions - Rearrangements
Fusion : MitelmanARMC9/EVL [2q37.1/14q32.2]  [t(2;14)(q37;q32)]  
Fusion : MitelmanCLMN/EVL [14q32.13/14q32.2]  [t(14;14)(q32;q32)]  
Fusion : MitelmanEVL/EML1 [14q32.2/14q32.2]  [t(14;14)(q32;q32)]  
Fusion: TCGAARMC9 2q37.1 EVL 14q32.2 LUAD
Fusion: TCGACLMN 14q32.13 EVL 14q32.2 BRCA
Fusion: TCGAEVL 14q32.2 EML1 14q32.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEVL [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EVL
dbVarEVL
ClinVarEVL
1000_GenomesEVL 
Exome Variant ServerEVL
ExAC (Exome Aggregation Consortium)EVL (select the gene name)
Genetic variants : HAPMAP51466
Genomic Variants (DGV)EVL [DGVbeta]
DECIPHER (Syndromes)14:100531751-100610573  ENSG00000196405
CONAN: Copy Number AnalysisEVL 
Mutations
ICGC Data PortalEVL 
TCGA Data PortalEVL 
Broad Tumor PortalEVL
OASIS PortalEVL [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEVL  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEVL
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EVL
DgiDB (Drug Gene Interaction Database)EVL
DoCM (Curated mutations)EVL (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EVL (select a term)
intoGenEVL
Cancer3DEVL(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenEVL
Genetic Testing Registry EVL
NextProtQ9UI08 [Medical]
TSGene51466
GENETestsEVL
Huge Navigator EVL [HugePedia]
snp3D : Map Gene to Disease51466
BioCentury BCIQEVL
ClinGenEVL
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51466
Chemical/Pharm GKB GenePA134890866
Clinical trialEVL
Miscellaneous
canSAR (ICR)EVL (select the gene name)
Probes
Litterature
PubMed46 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEVL
EVEXEVL
GoPubMedEVL
iHOPEVL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:05:06 CET 2017

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