Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

EVX1 (even-skipped homeobox 1)

Identity

Alias (NCBI)EVX-1
HGNC (Hugo) EVX1
HGNC Previous nameeve, even-skipped homeobox homolog 1 (Drosophila)
LocusID (NCBI) 2128
Atlas_Id 54293
Location 7p15.2  [Link to chromosome band 7p15]
Location_base_pair Starts at 27242802 and ends at 27247830 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
RUNX1 (21q22.12) / EVX1 (7p15.2)SYNRG (17q12) / EVX1 (7p15.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(7;21)(p15;q22) RUNX1/EVX1


External links

 

Nomenclature
HGNC (Hugo)EVX1   3506
Cards
Entrez_Gene (NCBI)EVX1    even-skipped homeobox 1
AliasesEVX-1
GeneCards (Weizmann)EVX1
Ensembl hg19 (Hinxton)ENSG00000106038 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000106038 [Gene_View]  ENSG00000106038 [Sequence]  chr7:27242802-27247830 [Contig_View]  EVX1 [Vega]
ICGC DataPortalENSG00000106038
TCGA cBioPortalEVX1
AceView (NCBI)EVX1
Genatlas (Paris)EVX1
SOURCE (Princeton)EVX1
Genetics Home Reference (NIH)EVX1
Genomic and cartography
GoldenPath hg38 (UCSC)EVX1  -     chr7:27242802-27247830 +  7p15.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EVX1  -     7p15.2   [Description]    (hg19-Feb_2009)
GoldenPathEVX1 - 7p15.2 [CytoView hg19]  EVX1 - 7p15.2 [CytoView hg38]
ImmunoBaseENSG00000106038
Genome Data Viewer NCBIEVX1 [Mapview hg19]  
OMIM142996   
Gene and transcription
Genbank (Entrez)AK298822 AK299188 AK314155 X60655
RefSeq transcript (Entrez)NM_001304519 NM_001304520 NM_001989
Consensus coding sequences : CCDS (NCBI)EVX1
Gene ExpressionEVX1 [ NCBI-GEO ]   EVX1 [ EBI - ARRAY_EXPRESS ]   EVX1 [ SEEK ]   EVX1 [ MEM ]
Gene Expression Viewer (FireBrowse)EVX1 [ Firebrowse - Broad ]
GenevisibleExpression of EVX1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2128
GTEX Portal (Tissue expression)EVX1
Human Protein AtlasENSG00000106038-EVX1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49640   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP49640  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP49640
PhosPhoSitePlusP49640
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-like_sf    Homeobox_CS    Homeobox_dom    Homeobox_metazoa   
Domain families : Pfam (Sanger)Homeodomain (PF00046)   
Domain families : Pfam (NCBI)pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)EVX1
SuperfamilyP49640
AlphaFold pdb e-kbP49640   
Human Protein Atlas [tissue]ENSG00000106038-EVX1 [tissue]
HPRD00876
Protein Interaction databases
DIP (DOE-UCLA)P49640
IntAct (EBI)P49640
BioGRIDEVX1
STRING (EMBL)EVX1
ZODIACEVX1
Ontologies - Pathways
QuickGOP49640
Ontology : AmiGOchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  nucleus  nucleoplasm  regulation of transcription by RNA polymerase II  embryo development ending in birth or egg hatching  axon  cell body  positive regulation of transcription by RNA polymerase II  spinal cord interneuron axon guidance  interneuron migration  sequence-specific double-stranded DNA binding  
Ontology : EGO-EBIchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  nucleus  nucleoplasm  regulation of transcription by RNA polymerase II  embryo development ending in birth or egg hatching  axon  cell body  positive regulation of transcription by RNA polymerase II  spinal cord interneuron axon guidance  interneuron migration  sequence-specific double-stranded DNA binding  
NDEx NetworkEVX1
Atlas of Cancer Signalling NetworkEVX1
Wikipedia pathwaysEVX1
Orthology - Evolution
OrthoDB2128
GeneTree (enSembl)ENSG00000106038
Phylogenetic Trees/Animal Genes : TreeFamEVX1
Homologs : HomoloGeneEVX1
Homology/Alignments : Family Browser (UCSC)EVX1
Gene fusions - Rearrangements
Fusion : MitelmanRUNX1/EVX1 [21q22.12/7p15.2]  
Fusion : QuiverEVX1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEVX1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EVX1
dbVarEVX1
ClinVarEVX1
MonarchEVX1
1000_GenomesEVX1 
Exome Variant ServerEVX1
GNOMAD BrowserENSG00000106038
Varsome BrowserEVX1
ACMGEVX1 variants
VarityP49640
Genomic Variants (DGV)EVX1 [DGVbeta]
DECIPHEREVX1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEVX1 
Mutations
ICGC Data PortalEVX1 
TCGA Data PortalEVX1 
Broad Tumor PortalEVX1
OASIS PortalEVX1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEVX1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DEVX1
Mutations and Diseases : HGMDEVX1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaEVX1
DgiDB (Drug Gene Interaction Database)EVX1
DoCM (Curated mutations)EVX1
CIViC (Clinical Interpretations of Variants in Cancer)EVX1
Cancer3DEVX1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM142996   
Orphanet
DisGeNETEVX1
MedgenEVX1
Genetic Testing Registry EVX1
NextProtP49640 [Medical]
GENETestsEVX1
Target ValidationEVX1
Huge Navigator EVX1 [HugePedia]
ClinGenEVX1
Clinical trials, drugs, therapy
MyCancerGenomeEVX1
Protein Interactions : CTDEVX1
Pharm GKB GenePA27919
PharosP49640
Clinical trialEVX1
Miscellaneous
canSAR (ICR)EVX1
HarmonizomeEVX1
DataMed IndexEVX1
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXEVX1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:08:36 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.