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EXD2 (exonuclease 3'-5' domain containing 2)

Identity

Alias_namesC14orf114
EXDL2
chromosome 14 open reading frame 114
exonuclease 3'-5' domain-like 2
Alias_symbol (synonym)FLJ10738
Other alias
HGNC (Hugo) EXD2
LocusID (NCBI) 55218
Atlas_Id 55696
Location 14q24.1  [Link to chromosome band 14q24]
Location_base_pair Starts at 69191477 and ends at 69244020 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
EXD2 (14q24.1) / EXD2 (14q24.1)EXD2 (14q24.1) / FAM162A (3q21.1)EXD2 (14q24.1) / GMEB2 (20q13.33)
HS3ST1 (4p15.33) / EXD2 (14q24.1)PTPRT (20q12) / EXD2 (14q24.1)SLIRP (14q24.3) / EXD2 (14q24.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EXD2   20217
Cards
Entrez_Gene (NCBI)EXD2  55218  exonuclease 3'-5' domain containing 2
AliasesC14orf114; EXDL2
GeneCards (Weizmann)EXD2
Ensembl hg19 (Hinxton)ENSG00000081177 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000081177 [Gene_View]  chr14:69191477-69244020 [Contig_View]  EXD2 [Vega]
ICGC DataPortalENSG00000081177
TCGA cBioPortalEXD2
AceView (NCBI)EXD2
Genatlas (Paris)EXD2
WikiGenes55218
SOURCE (Princeton)EXD2
Genetics Home Reference (NIH)EXD2
Genomic and cartography
GoldenPath hg38 (UCSC)EXD2  -     chr14:69191477-69244020 +  14q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EXD2  -     14q24.1   [Description]    (hg19-Feb_2009)
EnsemblEXD2 - 14q24.1 [CytoView hg19]  EXD2 - 14q24.1 [CytoView hg38]
Mapping of homologs : NCBIEXD2 [Mapview hg19]  EXD2 [Mapview hg38]
OMIM616940   
Gene and transcription
Genbank (Entrez)AK001600 AK056025 AK292563 AK295601 AL834434
RefSeq transcript (Entrez)NM_001193360 NM_001193361 NM_001193362 NM_001193363 NM_018199
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EXD2
Cluster EST : UnigeneHs.533878 [ NCBI ]
CGAP (NCI)Hs.533878
Alternative Splicing GalleryENSG00000081177
Gene ExpressionEXD2 [ NCBI-GEO ]   EXD2 [ EBI - ARRAY_EXPRESS ]   EXD2 [ SEEK ]   EXD2 [ MEM ]
Gene Expression Viewer (FireBrowse)EXD2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55218
GTEX Portal (Tissue expression)EXD2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NVH0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NVH0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NVH0
Splice isoforms : SwissVarQ9NVH0
PhosPhoSitePlusQ9NVH0
Domains : Interpro (EBI)3'-5'_exonuclease_dom    RNaseH-like_dom   
Domain families : Pfam (Sanger)DNA_pol_A_exo1 (PF01612)   
Domain families : Pfam (NCBI)pfam01612   
Domain families : Smart (EMBL)35EXOc (SM00474)  
Conserved Domain (NCBI)EXD2
DMDM Disease mutations55218
Blocks (Seattle)EXD2
SuperfamilyQ9NVH0
Human Protein AtlasENSG00000081177
Peptide AtlasQ9NVH0
HPRD16592
IPIIPI00915852   IPI00916247   IPI00384169   IPI00465113   
Protein Interaction databases
DIP (DOE-UCLA)Q9NVH0
IntAct (EBI)Q9NVH0
FunCoupENSG00000081177
BioGRIDEXD2
STRING (EMBL)EXD2
ZODIACEXD2
Ontologies - Pathways
QuickGOQ9NVH0
Ontology : AmiGOdouble-strand break repair via homologous recombination  DNA double-strand break processing  nucleic acid binding  protein binding  nucleus  cytoplasm  double-strand break repair  single-stranded DNA 3'-5' exodeoxyribonuclease activity  3'-5' exonuclease activity  exodeoxyribonuclease I activity  nucleic acid phosphodiester bond hydrolysis  
Ontology : EGO-EBIdouble-strand break repair via homologous recombination  DNA double-strand break processing  nucleic acid binding  protein binding  nucleus  cytoplasm  double-strand break repair  single-stranded DNA 3'-5' exodeoxyribonuclease activity  3'-5' exonuclease activity  exodeoxyribonuclease I activity  nucleic acid phosphodiester bond hydrolysis  
NDEx NetworkEXD2
Atlas of Cancer Signalling NetworkEXD2
Wikipedia pathwaysEXD2
Orthology - Evolution
OrthoDB55218
GeneTree (enSembl)ENSG00000081177
Phylogenetic Trees/Animal Genes : TreeFamEXD2
HOVERGENQ9NVH0
HOGENOMQ9NVH0
Homologs : HomoloGeneEXD2
Homology/Alignments : Family Browser (UCSC)EXD2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEXD2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EXD2
dbVarEXD2
ClinVarEXD2
1000_GenomesEXD2 
Exome Variant ServerEXD2
ExAC (Exome Aggregation Consortium)EXD2 (select the gene name)
Genetic variants : HAPMAP55218
Genomic Variants (DGV)EXD2 [DGVbeta]
DECIPHEREXD2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEXD2 
Mutations
ICGC Data PortalEXD2 
TCGA Data PortalEXD2 
Broad Tumor PortalEXD2
OASIS PortalEXD2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEXD2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEXD2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EXD2
DgiDB (Drug Gene Interaction Database)EXD2
DoCM (Curated mutations)EXD2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EXD2 (select a term)
intoGenEXD2
Cancer3DEXD2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616940   
Orphanet
MedgenEXD2
Genetic Testing Registry EXD2
NextProtQ9NVH0 [Medical]
TSGene55218
GENETestsEXD2
Target ValidationEXD2
Huge Navigator EXD2 [HugePedia]
snp3D : Map Gene to Disease55218
BioCentury BCIQEXD2
ClinGenEXD2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55218
Chemical/Pharm GKB GenePA164719421
Clinical trialEXD2
Miscellaneous
canSAR (ICR)EXD2 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEXD2
EVEXEXD2
GoPubMedEXD2
iHOPEXD2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:00:42 CEST 2017

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